Zobrazeno 1 - 4
of 4
pro vyhledávání: '"J. F. Scavulli"'
Publikováno v:
The Journal of rheumatology. 26(7)
Previously, we showed that rheumatoid arthritis (RA) had both antibodies and T cells specific for the QKRAA-encompassing Escherichia coli dnaJ protein. These findings suggest that the bacteria induced anti-dnaJ responses may cross react with the huma
Autor:
Dennis A. Carson, Alex J. MacGregor, E. C. Keystone, W. E. R. Ollier, Charles C. Berry, J. L. Nelson, Salvatore Albani, J. F. Scavulli, A. La Cava, J. C. Thorne
Publikováno v:
The Journal of clinical investigation. 100(3)
Rheumatoid arthritis (RA) is an autoimmune disease associated with HLA- DRbeta1 alleles which contain the QKRAA amino acid sequence in their third hypervariable region(s). The QKRAA sequence is also expressed by several human pathogens. We have shown
Publikováno v:
Arthritis & Rheumatism. 23:253-255
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 121(3)
With age, NZB mice lose their ability to develop a cytotoxic response after alloimmunization in vitro. This decline is shown to coincide with a diminution of T-helper cell activity as assessed by proliferation in mixed lymphocyte culture or in respon