Zobrazeno 1 - 10
of 50
pro vyhledávání: '"J. F. Rodrigues De Miranda"'
Autor:
J. F. Rodrigues De Miranda, C. A. M. Van Ginneken, Bob Th.R. Wentges, A. B. M. Klaassen, Y.J.B. van Megen
Publikováno v:
Journal of Allergy and Clinical Immunology. 87:521-529
Cholinergic nasal hyperresponsiveness in nasal allergy may be due to changes of the characteristics in muscarinic cholinergic receptors. Radioligand receptor binding and in vitro autoradiographic studies of nasal mucosa in nonallergic (NA) and allerg
Autor:
C. A. M. Van Ginneken, J. F. Rodrigues De Miranda, Peter H.G.M. Willems, J.J.H.H.M. De Pont, A. J. G. van Zwam
Publikováno v:
Journal of Receptor Research. 10:119-135
The muscarinic receptor in the rabbit pancreas was characterized with the use of the labeled ligand (3H)-(-)-quinuclidinyl-benzylate ((3H)-(-)-QNB). Specific binding of (3H)-(-)-QNB to pancreatic acini was found to be reversible and of high affinity,
Publikováno v:
British Journal of Clinical Pharmacology. 30:145S-147S
To study the relation between plasma adrenaline (AD) and noradrenaline (NA) and the beta 2-adrenoceptor number (Bmax) on lymphocytes these variables were measured in the following three groups: a) In 67 normotensive volunteers after a rest period of
Publikováno v:
Archives internationales de pharmacodynamie et de therapie. 322
The purpose of our study was to search for and classify prejunctional inhibitory muscarinic receptors in human bronchus with a wide range of muscarinic antagonists. Human bronchial airway smooth muscle strips, collected at thoracotomy from 54 subject
Autor:
E. A. M. Olde Riekerink, S. J. Graafsma, M. P. C. Hectors, Th. Thien, J. F. Rodrigues De Miranda, W. M. Blankesteijn
Publikováno v:
European journal of clinical pharmacology. 42(6)
The effect of beta-adrenoceptor antagonists (BAAs) differing in lipophilicity and partial agonist activity (PAA), and a full agonist, on the dissociation constant for [125I]-(-)- iodocyanopindolol binding to beta 2-adrenoceptors (KD) has been investi
Autor:
J. F. Rodrigues De Miranda, E. Willems-van Bree, A.M.L. Coenen, Jo M.H. Vossen, C.M. van Rijn
Publikováno v:
Journal of receptor research. 11(5)
Spontaneously occurring spike-wave discharges (SWD) in rats are used as a model for absence epilepsy in humans. In vitro, the binding parameters of 3H-Ro 5–4864, a ligand labelling the peripheral benzodiazepine receptor, were determined for brain m
Autor:
Carsten Strohmann, Ernst Mutschler, N. V. M. Rijntjes, Frans G. M. Russel, J. F. Rodrigues De Miranda, C. A. M. Van Ginneken, Nikola M. Rettenmayr, Reinhold Tacke, Günter Lambrecht
Publikováno v:
Naunyn-Schmiedeberg's archives of pharmacology. 342(2)
The pharmacokinetics of tritiated hexahydrosila- difenidol ([\(^3\)H]-HHSiD) were examined in rats. Furthermore, the distribution of radioactivity was studied by means of whole body autoradiography. After i. v. administration of 2.9 mg/kg HHSiD plus
Autor:
J. F. Rodrigues De Miranda, T.J.A.M. Van der Velden, C.M. van Rijn, O.R. Hommes, J.A.P. Hiel, M.G.P. Feenstra
Publikováno v:
Epilepsy research. 5(3)
The biochemical mechanism responsible for the convulsive effects of folates was investigated. The epileptogenic effects of folates were determined in vivo by quantification of the seizures following intracortical application in rats. The rank order o
Cholinergic and adrenergic abnormalities have been observed in nasal allergy and may be due to changes in pharmacological characteristics of neuroreceptors. Radioligand receptor binding studies demonstrated no significant changes in affinities or den
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4364655250ac8ac6e5bfb230d73e8c24
https://europepmc.org/articles/PMC1368124/
https://europepmc.org/articles/PMC1368124/
Autor:
J.J.H.H.M. De Pont, J. F. Rodrigues De Miranda, M. P. C. Hectors, Th. Thien, Peter H.G.M. Willems, L.J.H. van Tits, S. J. Graafsma
Publikováno v:
British journal of clinical pharmacology. 30
The effect of isotonic bicycle exercise on beta 2-adrenoceptors and cAMP production in lymphocytes was studied. The origin of the newly exposed receptors was studied by measuring radioligand binding in the presence of hydrophylic or lipophylic 'cold'