Výsledky vyhledávání - "J. F. Reilly"

Down-regulation of the Notch pathway mediated by a gamma-secretase inhibitor induces anti-tumour effects in mouse models of T-cell leukaemia

Publikováno v: British journal of pharmacology. 158(5)

gamma-Secretase inhibitors (GSIs) block NOTCH receptor cleavage and pathway activation and have been under clinical evaluation for the treatment of malignancies such as T-cell acute lymphoblastic leukaemia (T-ALL). The ability of GSIs to decrease T-A

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3bda9111cf4fe1ceb0096775ff848449
https://pubmed.ncbi.nlm.nih.gov/19775282

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Importin beta-mediated nuclear import of fibroblast growth factor receptor: role in cell proliferation

Autor: J F, Reilly, P A, Maher

Publikováno v: The Journal of Cell Biology

Although growth factor receptors are generally thought to carry out their role in signal transduction at the cell surface, many of these transmembrane proteins translocate to the nucleus after ligand stimulation. Here, we show that the nuclear transl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f03e929912c1b2347f8b6e4b2d09ed1a
https://pubmed.ncbi.nlm.nih.gov/11257130

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Regulation of astrocyte GFAP expression by TGF-beta1 and FGF-2

Autor: J F, Reilly, P A, Maher, V G, Kumari

Publikováno v: Glia. 22(2)

Astrocytes play a critical role in the development of the CNS and its response to injury and disease. A key indicator of astrocyte activation is the increased accumulation of intermediate filaments composed of glial fibrillary acidic protein (GFAP).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ea229c131ad0a603d36a0138c34458d3
https://pubmed.ncbi.nlm.nih.gov/9537840

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Hyperspherical polar analysis of bilocal particle model

Autor: J F Reilly

Publikováno v: Journal of Physics G: Nuclear Physics. 1:159-171

A simple bilocal model of elementary particles is studied by a wave equation method which utilises hyperspherical polar coordinates. This is a cluster model in which two quanta are associated through the agency of a potential which is a function of t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e2062dffde2ace5c9c1c3b5c71e4e40
https://doi.org/10.1088/0305-4616/1/2/003

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