Zobrazeno 1 - 10
of 269
pro vyhledávání: '"J. F. Muller"'
Autor:
Kwazi Gabuza, Thendo I Mabuda, Oelfah Patel, Noxolo Khuboni, Ruzayda van Aarde, Sylvia Riedel, Nonhlakanipho F Sangweni, Shantal Windvogel, Rabia Johnson, Christo J F Muller
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0297572 (2024)
BackgroundCurrently, it is acknowledged that vitamin E, insulin sensitizers and anti-diabetic drugs are used to manage non-alcoholic fatty liver disease (NAFLD), however, these therapeutic interventions harbour adverse side effects. Pioglitazone, an
Externí odkaz:
https://doaj.org/article/923f5bcac85143f5a913ae59314306e3
Autor:
Oelfah Patel, Christo J. F. Muller, Elizabeth Joubert, Bernd Rosenkranz, Johan Louw, Charles Awortwe
Publikováno v:
Frontiers in Clinical Diabetes and Healthcare, Vol 3 (2022)
Rooibos (Aspalathus linearis), an indigenous South African plant and its major flavonoid, aspalathin, exhibited positive effects on glycemia and dyslipidemia in animal studies. Limited evidence exists on the effects of rooibos extract taken in combin
Externí odkaz:
https://doaj.org/article/0c7231b6a27442e5809bc2b538b12803
Publikováno v:
PLoS ONE, Vol 17, Iss 5, p e0268551 (2022)
Oxidative stress and lipotoxicity effects on pancreatic β cells play a major role in the pathogenesis of type 2 diabetes (T2D). Flavonoids and antioxidants are under study for their cytoprotective effects and antidiabetic potential. In this study, w
Externí odkaz:
https://doaj.org/article/aff1f26c18dc40e8b4f05b64e277cba2
Autor:
Bi-Juan Wang, Shih-Han Huang, Cheng-Li Kao, Christo J F Muller, Ya-Pei Wang, Kai-Hsiung Chang, Hui-Chin Wen, Chien-Chih Yeh, Li-Jane Shih, Yung-Hsi Kao, Shu-Pin Huang, Chia-Yang Li, Chih-Pin Chuu
Publikováno v:
PLoS ONE, Vol 17, Iss 7, p e0270803 (2022)
Enzalutamide, a nonsteroidal antiandrogen, significantly prolonged the survival of patients with metastatic castration-resistant prostate cancer (CRPC). However, patients receiving enzalutamide frequently develop drug resistance. Rooibos (Aspalathus
Externí odkaz:
https://doaj.org/article/7506868f41ab4ce3b271abc6e747e364
Autor:
Vinesh Maharaj, Chidinma Christiana Ezeofor, Dashnie Naidoo Maharaj, Christo J. F. Muller, Nnini Jennifer Obonye
Publikováno v:
Molecules, Vol 27, Iss 22, p 8095 (2022)
Diabetes, a prevalent metabolic condition with a wide range of complications, is fast becoming a global health crisis. Herbal medicine and enhanced extracts are some of the therapeutic options used in the management of diabetes mellitus. The plant-de
Externí odkaz:
https://doaj.org/article/c7e9b85fb1114ab398668093a0054520
Autor:
Kazumi Yagasaki, Christo J. F. Muller
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 14, p 7765 (2022)
There are three main types of diabetes, namely, type 1 diabetes, type 2 diabetes (T2D), and diabetes in pregnancy (gestational diabetes) [...]
Externí odkaz:
https://doaj.org/article/30d1c3caa2664429a0134b8d9407fd8a
Autor:
Yonela Ntamo, Ebrahim Samodien, Joleen Burger, Nolan Muller, Christo J. F. Muller, Nireshni Chellan
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Externí odkaz:
https://doaj.org/article/70ac47f604a44fb7a8d8174237beb809
Autor:
Yonela Ntamo, Ebrahim Samodien, Joleen Burger, Nolan Muller, Christo J. F. Muller, Nireshni Chellan
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2021)
Over the years, immortalized rodent β-cell lines such as RIN, HIT, MIN, βTC, and INS-1 have been used to investigate pancreatic β-cell physiology using conventional two-dimensional (2D) culture techniques. However, physical and physiological limit
Externí odkaz:
https://doaj.org/article/132ae393cc1d43b2875484216b13d5c8
Autor:
Phiwayinkosi V. Dludla, Tawanda M. Nyambuya, Patrick Orlando, Sonia Silvestri, Vuyolwethu Mxinwa, Kabelo Mokgalaboni, Bongani B. Nkambule, Johan Louw, Christo J. F. Muller, Luca Tiano
Publikováno v:
Endocrinology, Diabetes & Metabolism, Vol 3, Iss 2, Pp n/a-n/a (2020)
Abstract Aims Coenzyme Q10 (CoQ10) is well known for its beneficial effects in cardiovascular disease (CVD); however, reported evidence has not been precisely synthesized to better inform on its impact in protecting against cardiovascular‐related c
Externí odkaz:
https://doaj.org/article/03552f799d6042459dd846a1dc4c51da
Autor:
Sithandiwe E. Mazibuko-Mbeje, Sinenhlanhla X. H. Mthembu, Andani Tshiitamune, Ndivhuwo Muvhulawa, Fikile T. Mthiyane, Khanyisani Ziqubu, Christo J. F. Muller, Phiwayinkosi V. Dludla
Publikováno v:
Molecules, Vol 26, Iss 20, p 6154 (2021)
Our group has progressively reported on the impact of bioactive compounds found in rooibos (Aspalathus linearis) and their capacity to modulate glucose homeostasis to improve metabolic function in experimental models of type 2 diabetes. In the curren
Externí odkaz:
https://doaj.org/article/a7ec7e790925443b88dc72295bab5866