Výsledky vyhledávání - "J. F. MacMaster"

Regulation of inflammatory responses by oncostatin M

Autor: P M, Wallace, J F, MacMaster, K A, Rouleau, T J, Brown, J K, Loy, K L, Donaldson, A F, Wahl

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 162(9)

Oncostatin M (OM) is a pleiotropic cytokine produced late in the activation cycle of T cells and macrophages. In vitro it shares properties with related proteins of the IL-6 family of cytokines; however, its in vivo properties and physiological funct

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::eaa02fd8b6db2923a34ad99ba28c2215
https://pubmed.ncbi.nlm.nih.gov/10228036

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Thrombocytopoietic properties of oncostatin M

Autor: P M, Wallace, J F, MacMaster, J R, Rillema, J, Peng, S A, Burstein, M, Shoyab

Publikováno v: Blood. 86(4)

Oncostatin M (OM) is a 28-kD glycoprotein that exhibits a panoply of biologic effects. Based on histologic observations of increased splenic megakaryocytes in nude mice implanted with an OM-secreting cell line, the thrombocytopoietic properties of OM

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::551d74204818621f0a242e72aea73d42
https://pubmed.ncbi.nlm.nih.gov/7632937

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In vitro and in vivo activities of a doxorubicin prodrug in combination with monoclonal antibody beta-lactamase conjugates

Autor: H P, Svensson, V M, Vrudhula, J E, Emswiler, J F, MacMaster, W L, Cosand, P D, Senter, P M, Wallace

Publikováno v: Cancer research. 55(11)

A cephalosporin derivative of doxorubicin (C-Dox) was evaluated as a prodrug for activation by mAb conjugates of the beta-lactamase from Enterobacter cloacae P99 (beta L; EC 3.5.2.6). The conjugates consisted of beta L and the F(ab') fragments of eit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::87aee6ecca80f2257a1babbc319c9895
https://pubmed.ncbi.nlm.nih.gov/7757987

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Intratumoral generation of 5-fluorouracil mediated by an antibody-cytosine deaminase conjugate in combination with 5-fluorocytosine

Autor: P M, Wallace, J F, MacMaster, V F, Smith, D E, Kerr, P D, Senter, W L, Cosand

Publikováno v: Cancer research. 54(10)

Cytosine deaminase (CD) is a microbial enzyme that can convert the antifungal agent 5-fluorocytosine (5-FC) into the antitumor agent, 5-fluorouracil (5-FU). The enzyme was chemically conjugated to the L6 monoclonal antibody, forming a conjugate that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c030357c099078550e5340727ee458e3
https://pubmed.ncbi.nlm.nih.gov/8168103

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Akademický článek

An inhibitor of I?B kinase, BMS-345541, blocks endothelial cell adhesion molecule expression and reduces the severity of dextran sulfate sodium-induced colitis in mice.

Autor: J. F. MacMaster, D. M. Dambach, D. B. Lee, K. K. Berry, Y. Qiu, F. C. Zusi, J. R. Burke

Publikováno v: Inflammation Research; Nov2003, Vol. 52 Issue 12, p508-511, 4p

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