Zobrazeno 1 - 3
of 3
pro vyhledávání: '"J. F. Di Mari"'
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 293:G719-G728
Proinflammatory cytokines and eicosanoids are central players in intestinal inflammation. IL-1, a key cytokine associated with intestinal mucosal inflammation, induces COX-2 expression in human colonic myofibroblasts (CMF) and increased prostaglandin
Autor:
Patrick A. Adegboyega, K. F. Pang, J. F. Di Mari, Victor E. Reyes, R. A. Tamerisa, Jamal I. Saada, Randy C. Mifflin, Carlos A. Barrera, Don W. Powell, David A. Bland, Giovanni Suarez
Publikováno v:
Annals of the New York Academy of Sciences. 1029:379-381
Stromal cells, such as myofibroblasts and fibroblasts, represent a significant fraction of MHC class II-positive cells in the normal human colonic lamina propria, suggesting they may play an important role in CD4(+) T cell regulation in a tolerogenic
Publikováno v:
American journal of physiology. Gastrointestinal and liver physiology. 289(1)
Intestinal myofibroblasts are α-smooth muscle actin-positive stromal cells that exist as a syncytium with fibroblasts and mural cells in the lamina propria of the gut. Through expression and secretion of cytokines, chemokines, growth factors, prosta