Výsledky vyhledávání - "J. F. Codrington"

The Usefulness of Sequence Analysis of Amplified DNA for the Identification of δ Chain Variants

Autor: Ph. Beris, Adekunle Adekile, J. F. Codrington, Louis D. Wadsworth, H-W. Li, Gino Schilirò, Titus H.J. Huisman

Publikováno v: Hemoglobin. 15:77-84

A method of identifying delta chain variants using relatively small volumes of blood is described. The procedure consists of the amplification of two segments of genomic DNA with two sets of delta chain specific primers and sequencing of the three ex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d00650c5027c9db9224bba591a6291e8
https://doi.org/10.3109/03630269109072486

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Observations on the levels of Hb A2 in patients with different beta- thalassemia mutations and a delta chain variant

Autor: H.-W. Li, J. F. Codrington, Titus H.J. Huisman, L-H. Gu, Ferdane Kutlar, M. Ramachandran

Publikováno v: Blood. 76:1246-1249

Hb A2 and its variant B2 (alpha 2 delta 2(16)(A13)Gly----Arg) were quantitated in the blood of subjects with three different types of beta- thalassemia and with the delta-B2 anomaly in cis or in trans to the beta-thalassemia determinant. In one famil

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fcf17fdd021ccaf43d6bda61e9520f0c
https://doi.org/10.1182/blood.v76.6.1246.bloodjournal7661246

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Hemoglobin Birmingham and hemoglobin Galicia: two unstable beta chain variants characterized by small deletions and insertions

Autor: I Rodriguez, Ferdane Kutlar, Brooke B. Webber, J. B. Wilson, JT Prchal, J. F. Codrington, J. M. De Pablos, Abdullah Kutlar, H. Hu, KM Hall

Publikováno v: Blood. 75:1883-1887

Two unstable hemoglobins (Hbs) causing rather severe hemolytic anemia have been characterized. The beta chain of Hb Birmingham, found in an adult black man, is characterized by the loss of -Leu-Ala-His-Lys- at positions 141, 142, 143, and 144 and the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::863c73306e999cc7a536fc8b0f70b3f2
https://doi.org/10.1182/blood.v75.9.1883.bloodjournal7591883

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Compound Heterozygosity for a Mild β+ and a Rare β°-Thalassemia Allele

Autor: J. H. Wisse, J. F. Codrington, Ferdane Kutlar, J. Anijs, Titus H.J. Huisman, H.-W. Li, F. A. Codrington, M. Ramachandran

Publikováno v: Acta Haematologica. 84:135-138

Hematological and hemoglobin composition data are presented for 14 members of a Surinam family (and for 1 unrelated subject) with either a β-thalassemia heterozygosity [5 with the -29 (A – G) β+

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f6a77d849e60145b146ec423ed275374
https://doi.org/10.1159/000205050

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Hb Sun Prae or α213o(H13)Ala → Proβ2A New Unstable Variant Occurring In Low Quantities

Autor: Ferdane Kutlar, D. R. Harkness, Abdullah Kutlar, J. F. Codrington, M. Harkness, J. B. Wilson, Brooke B. Webber, Titus H.J. Huisman

Publikováno v: Hemoglobin. 14:479-489

A severe hemolytic anemia with microcytosis and hypochromia was present in a young adopted Indian patient. Reversed phase high performance liquid chromatographic methodology and heat stability tests detected an unstable α chain which was present in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2514346611332229a898c849192b9438
https://doi.org/10.3109/03630269009005801

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Beta S haplotypes in various world populations

Autor: C, Oner, A J, Dimovski, N F, Olivieri, G, Schiliro, J F, Codrington, S, Fattoum, A D, Adekile, R, Oner, G T, Yüregir, C, Altay

Publikováno v: Human genetics. 89(1)

We have determined the beta S haplotypes in 709 patients with sickle cell anemia, 30 with SC disease, 91 with S-beta-thalassemia, and in 322 Hb S heterozygotes from different countries. The methodology concerned the detection of mutations in the prom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6eabf82a7fd35c837d5ff63eb2a5e4d4
https://pubmed.ncbi.nlm.nih.gov/1577473

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Observations on the levels of Hb A2 in patients with different beta-thalassemia mutations and a delta chain variant

Autor: J F, Codrington, H W, Li, F, Kutlar, L H, Gu, M, Ramachandran, T H, Huisman

Publikováno v: Blood. 76(6)

Hb A2 and its variant B2 (alpha 2 delta 2(16)(A13)Gly----Arg) were quantitated in the blood of subjects with three different types of beta-thalassemia and with the delta-B2 anomaly in cis or in trans to the beta-thalassemia determinant. In one family

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::54ed7e8cf1a6c6b96d91c1d5b942383f
https://pubmed.ncbi.nlm.nih.gov/1698102

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Hb Icaria-Hb H disease: identification of the Hb Icaria mutation through analysis of amplified DNA

Autor: J. M. Gonzalez-Redondo, O. Josifovska, Titus H.J. Huisman, N. Nikolov, J. F. Codrington, Georgi D. Efremov, C. Oner

Publikováno v: British journal of haematology. 75(2)

Hb Icaria-Hb H disease was observed in a Yugoslavian teenager who exhibited moderate anaemia with severe microcytosis and hypochromia and 16% Hb H. Four of his relatives were Hb Icaria heterozygotes; their haematological data were comparable to those

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f8e58dbbc2919b3ccb3facf066da8cf
https://pubmed.ncbi.nlm.nih.gov/2372512

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