Zobrazeno 1 - 10 of 30 pro vyhledávání: '"J. F. Chantot"'
1
Synthesis and Antibacterial Activity of Ketolides (6-O-Methyl-3-oxoerythromycin Derivatives): A New Class of Antibacterials Highly Potent Against Macrolide-Resistant and -Susceptible Respiratory Pathogens
Autor: Véronique Loyau, Alain Bonnefoy, Solange Gouin D'ambrieres, A Dussarat, Nicole Tessot, C. Fromentin, Sylvette Lachaud, Patrick Laurin, Jean-Michel Auger, Yannick Benedetti, Francois Bretin, J. F. Chantot, C. Agouridas, A. Denis, Le Martret Odile
Publikováno v: Journal of Medicinal Chemistry. 41:4080-4100
In the search for new antibiotics active against macrolide-resistant pneumococci and Haemophilus influenzae, we synthesized a new class of 3-oxo-6-O-methylerythromycin derivatives, so-called "ketolides". A keto function was introduced in position 3 a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec9a59ca094217e91a9cd1a14deb0276
https://doi.org/10.1021/jm980240d
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2
Ketolides lack inducibility properties of MLS(B) resistance phenotype
Autor: C Agouridas, A Bonnefoy, J F Chantot, A M Girard
Publikováno v: The Journal of antimicrobial chemotherapy. 40(1)
Ketolides belong to a new class of semi-synthetic 14-membered-ring macrolides, which differ from erythromycin A by having a 3-keto group instead of the neutral sugar L-cladinose. The ability of these molecules and their L-cladinose counterparts to in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61b81800564f148782815fde0ad69123
https://pubmed.ncbi.nlm.nih.gov/9249208
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3
[Study of the bactericidal effect of cefpodoxime using an in vitro pharmacokinetic model]
Autor: A, Caisson, J F, Chantot
Publikováno v: Pathologie-biologie. 39(8)
Cefpodoxime is a new oral prodrug antibiotic. Following absorption from the proximal intestine, non-specific esterases hydrolyze this cleavable ester, releasing cefpodoxime, a new broad-spectrum third-generation cephalosporin with sustained plasma le
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5036125f90b8a2c235d7a43e4bb7d94f
https://pubmed.ncbi.nlm.nih.gov/1762835
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4
[RU 51807 (cefpodoxime proxetil). In vitro and in vivo antibacterial activity of a new orally administered active cephalosporin]
Autor: J F, Chantot, P, Mauvais
Publikováno v: Pathologie-biologie. 39(1)
Cefpodoxime proxetil (RU 51807) is an enterally absorbed ester prodrug which is rapidly cleaved in vivo after oral administration, with release of the active free acid metabolite cefpodoxime. The in vitro antibacterial activity of the sodium salt of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fefabaa3fd8de1d5729620552c134829
https://pubmed.ncbi.nlm.nih.gov/1901403
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7
[HR 810 (cefpirome). Experimental evaluation of the in vitro and in vivo antibiotic activity of a new amino-2-thiazole methoxy- imino cephalosporin]
Autor: J F, Chantot, A, Bryskier
Publikováno v: Pathologie-biologie. 33(5 Pt 2)
HR 810 or cefpirome is a new amino thiazole cephalosporin whose specific characteristic is a cyclopentenopyridinium group in position 3 of the cephem nucleus. This structure is responsible for a broad spectrum of activity, covering Enterobacteriaceae
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::08c53e95da4769584c0a95fcd43e3dba
https://pubmed.ncbi.nlm.nih.gov/3937124
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