Zobrazeno 1 - 10
of 25
pro vyhledávání: '"J. F. Carpenter"'
Publikováno v:
Alimentary pharmacologytherapeutics. 38(10)
SummaryBackground Anti-drug antibodies (ADAs) to biologic therapies contribute to the loss of response and infusion reactions to anti-TNF drugs in patients with inflammatory bowel disease (IBD). The reasons behind this immunogenicity are complex, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57e776c63944aa12be5680b3a7fbd463
https://pubmed.ncbi.nlm.nih.gov/24118102
https://pubmed.ncbi.nlm.nih.gov/24118102
Publikováno v:
ChemInform. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dcd5ed4f4fc98847e6c2bea19d01a806
https://doi.org/10.1002/chin.199504316
https://doi.org/10.1002/chin.199504316
Publikováno v:
ChemInform. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d2536d34783402cd4bf5539f1ad5518
https://doi.org/10.1002/chin.199504320
https://doi.org/10.1002/chin.199504320
Publikováno v:
Journal of Vascular Surgery. 11:94-102
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c69eda761a5f2bbc8a37bb6e22c923ef
https://doi.org/10.1067/mva.1990.16919
https://doi.org/10.1067/mva.1990.16919
Publikováno v:
The Journal of biological chemistry. 276(50)
Two different types of insoluble, non-native aggregates of recombinant human growth hormone were formed by agitation in buffer or buffer containing 0.75 m guanidine HCl (GdnHCl) and characterized by infrared and second derivative UV spectroscopies. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::74442608df4eb0c13a6c4842d5b56bbc
https://pubmed.ncbi.nlm.nih.gov/11591710
https://pubmed.ncbi.nlm.nih.gov/11591710
Autor:
T H, Yang, J L, Cleland, X, Lam, J D, Meyer, L S, Jones, T W, Randolph, M C, Manning, J F, Carpenter
Publikováno v:
Journal of pharmaceutical sciences. 89(11)
Metal-induced precipitation of protein therapeutics is being used and further developed as a processing step in protein formulation and may have utility in protein purification and bulk storage. In such processes, it is imperative that native protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aa8e561fea8946accc0198e1bff6b9f7
https://pubmed.ncbi.nlm.nih.gov/11015692
https://pubmed.ncbi.nlm.nih.gov/11015692
Publikováno v:
Pharmaceutical research. 17(4)
To assess the impact of various bioprocessing steps on the stability of freshly precipitated human serum albumin (HSA) obtained from pooled human plasma.After initial precipitation of HSA from plasma, the resultant paste is either (a) lyophilized or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4f45423e1fcc6b046a2f4de44e70a43b
https://pubmed.ncbi.nlm.nih.gov/10870981
https://pubmed.ncbi.nlm.nih.gov/10870981
Publikováno v:
Journal of pharmaceutical sciences. 89(2)
The storage stability of a dry protein depends on the structure of the dried protein, as well as on the storage temperature relative to the glass transition temperature of the dried preparation. Disaccharides are known to preserve the native conforma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8e2f6a69cc9fc4cdfbd8d780b6cc5cb1
https://pubmed.ncbi.nlm.nih.gov/10688749
https://pubmed.ncbi.nlm.nih.gov/10688749
Publikováno v:
Methods in enzymology. 309
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9af109fcd233f81797521093a7b24d65
https://pubmed.ncbi.nlm.nih.gov/10507028
https://pubmed.ncbi.nlm.nih.gov/10507028
Publikováno v:
Biotechnology and bioengineering. 63(2)
Hemoglobin has been previously shown to unfold during freeze drying when lyophilized from formulations that undergo freeze-concentration induced phase separation (Heller et al. 1997. Biotechnol Prog 13:590-596). In this report, we show that such dama
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::acc53a6e8a5d25473bbda417fa7cb293
https://pubmed.ncbi.nlm.nih.gov/10099593
https://pubmed.ncbi.nlm.nih.gov/10099593