Zobrazeno 1 - 10
of 150
pro vyhledávání: '"J. Evan Sadler"'
Autor:
Shruti, Chaturvedi, Ana G, Antun, Andrew M, Farland, Ryan, Woods, Ara, Metjian, Yara A, Park, Gustaaf, de Ridder, Briana, Gibson, Raj S, Kasthuri, Darla K, Liles, Frank, Akwaa, Todd, Clover, Lisa, Baumann Kreuziger, J Evan, Sadler, Meera, Sridharan, Ronald S, Go, Keith R, McCrae, Harsh Vardhan, Upreti, Angela, Liu, Ming Y, Lim, Radhika, Gangaraju, X Long, Zheng, Jay S, Raval, Camila, Masias, Spero R, Cataland, Andrew, Johnson, Elizabeth, Davis, Michael D, Evans, Marshall A, Mazepa
Publikováno v:
Blood. 140:1335-1344
Immune-mediated thrombotic thrombocytopenic purpura (iTTP) is characterized by recurring episodes of thrombotic microangiopathy, causing ischemic organ impairment. Black patients are overrepresented in iTTP cohorts in the United States, but racial di
Autor:
Lisa A. Westfield, Ara Metjian, Joshua Muia, Ayad Hamdan, Patricia Nieters, J. Evan Sadler, Anita Rodrigues, Ana G. Antun, Jeffrey I. Zwicker, Leili Dolatshahi
Publikováno v:
Blood
TO THE EDITOR: The introduction of plasmapheresis with plasma exchange has increased survival in patients with thrombotic thrombocytopenic purpura (TTP) from
Autor:
J. Evan Sadler
Publikováno v:
Blood. 130:1181-1188
The discovery of a disintegrin-like and metalloproteinase with thrombospondin type 1 motif, member 13 (ADAMTS13) revolutionized our approach to thrombotic thrombocytopenic purpura (TTP). Inherited or acquired ADAMTS13 deficiency allows the unrestrain
Autor:
Karen Vanhoorelbeke, Garima Gupta, Lisa A. Westfield, Jian Zhu, Joshua Muia, Niraj H. Tolia, J. Evan Sadler
Human ADAMTS13 is a multidomain protein with metalloprotease (M), disintegrin-like (D), thrombospondin-1 (T), Cys-rich (C), and spacer (S) domains, followed by 7 additional T domains and 2 CUB (complement components C1r and C1s, sea urchin protein Ue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::007b7b6959f15a5ee803c2fafc51b68d
https://lirias.kuleuven.be/handle/123456789/648516
https://lirias.kuleuven.be/handle/123456789/648516
Autor:
Jian Zhu, Lisa A. Westfield, Garima Gupta, Joshua Muia, Suellen Greco, Karen Vanhoorelbeke, J. Evan Sadler
The metalloprotease ADAMTS13 (a disintegrin and metalloprotease with thrombospondin type 1 repeats member 13) prevents microvascular thrombosis by cleaving von Willebrand factor (VWF) within platelet-rich thrombi, and cleavage depends on allosteric a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6a7816ae8cf9321bd0bfc252022440d
https://lirias.kuleuven.be/handle/123456789/648517
https://lirias.kuleuven.be/handle/123456789/648517
Autor:
Gustaaf de Ridder, Lisa Baumann Kreuziger, Keith R. McCrae, Andrew M. Farland, Rahil Kohli, Meera Sridharan, Ming Y. Lim, Darla K. Liles, Spero R. Cataland, X. Long Zheng, Elizabeth E. Davis, Ana G Antun, Radhika Gangaraju, Raj S. Kasthuri, Yara A. Park, Ronald S. Go, Frank Akwaa, Andrew D. Johnson, Kristin Bagby, Jay S. Raval, Harsh Vardhan Upreti, Ara Metjian, Briana Gibson, Michael D. Evans, Susan Eubanks, Nicole K. Kocher, J. Evan Sadler, Ryan R Woods, Shruti Chaturvedi, Mazepa A. Marshall
Publikováno v:
Blood. 134:90-90
Introduction The United States Thrombotic Microangiopathy (USTMA) Consortium consists of high-volume US referral centers that are committed to collaborative research in TMAs. The USTMA Immune Thrombotic Thrombocytopenic Purpura (iTTP) registry has co
Autor:
Harsh Vardhan Upreti, Shruti Chaturvedi, Elizabeth E. Davis, Radhika Gangaraju, Rahil Kohli, Meera Sridharan, Darla K. Liles, Frank Akwaa, Gustaaf de Ridder, Andrew D. Johnson, Spero R. Cataland, Ming Y. Lim, Angela Liu, X. Long Zheng, Kristin Bagby, Ana G Antun, Jay S. Raval, Nicole K. Kocher, Keith R. McCrae, J. Evan Sadler, Yara A. Park, Andrew M. Farland, Ara Metjian, Marshall A. Mazepa, Briana Gibson, Lisa Baumann Kreuziger, Susan Eubanks, Ronald S. Go, Raj S. Kasthuri, Ryan R Woods
Publikováno v:
Blood. 134:1066-1066
Background: Immune thrombotic thrombocytopenic purpura (iTTP) is a potentially fatal hematologic disorder characterized by thrombocytopenia, microangiopathic hemolytic anemia, and ischemic organ impairment. The incidence of iTTP is higher among Afric
Autor:
J. Evan Sadler, Brooke Sadler
Publikováno v:
Neurology. 92:1157-1158
Autor:
Joshua Muia, Sandra L. Haberichter, Lisa A. Westfield, Kenneth D. Friedman, Garima Gupta, John E. Heuser, Hendrik B. Feys, Jian Zhu, Niraj H. Tolia, Karen Vanhoorelbeke, J. Evan Sadler, Louis Deforche, Robyn Roth
Publikováno v:
Proceedings of the National Academy of Sciences. 111:18584-18589
The metalloprotease ADAMTS13 cleaves von Willebrand factor (VWF) within endovascular platelet aggregates, and ADAMTS13 deficiency causes fatal microvascular thrombosis. The proximal metalloprotease (M), disintegrin-like (D), thrombospondin-1 (T), Cys