Zobrazeno 1 - 10
of 347
pro vyhledávání: '"J. Eppig"'
Autor:
Richard M, Schultz, John J, Eppig
Publikováno v:
Nature cell biology. 23(1)
Autor:
Benfang Ruan, Shinya Watanabe, John J. Eppig, Christopher Kwoh, Natasha Dzidic, Jihai Pang, William K. Wilson, George J. Schroepfer, Jr.
Publikováno v:
Journal of Lipid Research, Vol 39, Iss 10, Pp 2005-2020 (1998)
4,4-Dimethyl-5α-cholesta-8,14,24-trien-3β-ol (I) from human follicular fluid and 4,4-dimethyl-5α-cholesta-8,24-dien-3β-ol (II) from bull testes have been reported to activate meiosis in mouse oocytes (Byskov et al., 1995. Nature. 374: 559–562).
Externí odkaz:
https://doaj.org/article/6e1289a21e394d7890b29866ce405844
Publikováno v:
PLoS ONE, Vol 4, Iss 10, p e7479 (2009)
Gene expression microarrays have provided many insights into changes in gene expression patterns between different tissue types, developmental stages, and disease states. Analyses of these data focused primarily measuring the relative abundance of tr
Externí odkaz:
https://doaj.org/article/eff0193497d3460392f3a5441e0759e3
Autor:
Jeremy O Ward, Laura G Reinholdt, William W Motley, Lisa M Niswander, Dekker C Deacon, Laurie B Griffin, Kristofor K Langlais, Vickie L Backus, Kerry J Schimenti, Marilyn J O'Brien, John J Eppig, John C Schimenti
Publikováno v:
PLoS Genetics, Vol 3, Iss 8, p e139 (2007)
Crossing over during meiotic prophase I is required for sexual reproduction in mice and contributes to genome-wide genetic diversity. Here we report on the characterization of an N-ethyl-N-nitrosourea-induced, recessive allele called mei4, which caus
Externí odkaz:
https://doaj.org/article/7b0560d3de224235b846cf2a83a09ae2
Autor:
Marilyn J. O'Brien, Carl Lessard, John C. Schimenti, Mary Ann Handel, Jianjun Hu, John J. Eppig, Laura G. Reinholdt, Charles J Longstaff, Kristina Palmer
Publikováno v:
Molecular reproduction and development. 86(4)
Given attention to both contraception and treatment of infertility, there is a need to identify genes and sequence variants required for mammalian fertility. Recent unbiased mutagenesis strategies have expanded horizons of genetic control of reproduc
Autor:
Yaoxue Yin, Teng Zhang, Lanying Shi, Tao Sun, Jiahao Sha, Hong Yin, Yueshuai Guo, Guangyi Cao, Xuejiang Guo, You-Qiang Su, Xiaoyun Zhang, Hao Wang, Hui Li, John J. Eppig, Jing Guo
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 115(23)
MTOR (mechanistic target of rapamycin) is a widely recognized integrator of signals and pathways key for cellular metabolism, proliferation, and differentiation. Here we show that conditional knockout (cKO) of Mtor in either primordial or growing ooc
Autor:
John J. Eppig
Publikováno v:
Current biology : CB. 28(8)
El-Hayek et al. show that the growing oocyte induces the somatic cells surrounding it to continuously generate specialized filopodia which penetrate its extracellular coat and permit essential germ line-somatic communication. Fewer filopodia couple t
Autor:
Neil Bahroos, Grace Teng, Malay Mandal, David G. Schatz, John J Eppig, Keith M. Hamel, Jigyasa H. Tuteja, Marcus R. Clark, Mark Maienschein-Cline, Azusa Tanaka, Jeffrey J. Bunker
Publikováno v:
Nature immunology
B lymphopoiesis requires that immunoglobulin genes be accessible to RAG1-RAG2 recombinase. However, the RAG proteins bind widely to open chromatin, which suggests that additional mechanisms must restrict RAG-mediated DNA cleavage. Here we show that d
Autor:
Rabindranath De La Fuente, Shrivatsav Pattabiraman, John C. Schimenti, John J. Eppig, Daniela I. Guisado, Claudia Baumann
Publikováno v:
The Journal of Cell Biology
Exhibiting sexually dimorphic roles in mice, BRWD1 is essential for proper meiotic chromosome condensation and telomere structure during oogenesis and for haploid-specific gene transcription during postmeiotic sperm differentiation.
Postmeiotic
Postmeiotic
Autor:
Fengyun Sun, Philip W. Jordan, John J. Eppig, Marilyn J. O'Brien, Grace M. Hwang, Mary Ann Handel
Publikováno v:
Development.
SMC complexes include three major classes: cohesin, condensin, and SMC5/6. However, the localization pattern and genetic requirements for the SMC5/6 complex during mammalian oogenesis had not previously been examined. In mouse oocytes, the SMC5/6 com