Výsledky vyhledávání - "J. Emanuel Ramos de Carvalho"

Akademický článek

Involvement of the ubiquitin-proteasome system in the expression of extracellular matrix genes in retinal pigment epithelial cells

Autor: J. Emanuel Ramos de Carvalho, Milan T. Verwoert, Ilse M.C. Vogels, Eric A. Reits, Cornelis J.F. Van Noorden, Ingeborg Klaassen, Reinier O. Schlingemann

Publikováno v: Biochemistry and Biophysics Reports, Vol 13, Iss , Pp 83-92 (2018)

Emerging evidence suggests that dysfunction of the ubiquitin-proteasome system is involved in the pathogenesis of numerous senile degenerative diseases including retinal disorders. The aim of this study was to assess whether there is a link between p

Externí odkaz: https://doaj.org/article/73e3bd5ff407494f882b26db49836d2f

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Volume rendering of superficial optic disc drusen

Autor: Catherine A Egan, Pascal W. Hasler, J. Emanuel Ramos de Carvalho, Axel Petzold, Adnan Tufail, Sandrine Zweifel, Peter Maloca

Publikováno v: Spektrum der Augenheilkunde. 31:288-293

Optic disc drusen (ODD) are calcified deposits potentially caused by disturbances in axonal metabolism. The clinical course and visual impairment of ODD is usually mild; however, significant ocular morbidity may occur, such as visual field defects an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b58982729238a7a5587355bbf5637c69
https://doi.org/10.1007/s00717-017-0359-4

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A 30 s test for quantitative assessment of a relative afferent pupillary defect (RAPD): the infrared pupillary asymmetry (IPA)

Autor: Axel Petzold, Nathalie Stéphanie Meneguette, J. Emanuel Ramos de Carvalho

Publikováno v: Meneguette, N S, de Carvalho, J E R & Petzold, A 2019, ' A 30 s test for quantitative assessment of a relative afferent pupillary defect (RAPD): the infrared pupillary asymmetry (IPA) ', Journal of Neurology, vol. 266, no. 4, pp. 969-974 . https://doi.org/10.1007/s00415-019-09223-1
Journal of Neurology, 266(4), 969-974. D. Steinkopff-Verlag

Background: Detection of a relative afferent pupillary defect (RAPD) by the swinging-light test can be challenging in clinical practice (dark eyes, anisocoria, dark environment). We developed a new method of RAPD quantification based on the recording

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b580aca5d38d179282d2d0829fb98507
https://pubmed.ncbi.nlm.nih.gov/30746557

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Safety and Feasibility of a Novel Sparse Optical Coherence Tomography Device for Patient-Delivered Retina Home Monitoring

Autor: Pascal W. Hasler, Peter Maloca, Adnan Tufail, Patrik Arnold, J. Emanuel Ramos de Carvalho, Mooser Matthias, Justus G. Garweg, Daniel Barthelmes, Sandrine Zweifel, Heinrich Gerding, Hendrik P. N. Scholl, Catherine A Egan, Konstantinos Balaskas, Tjebo F. C. Heeren

Publikováno v: Maloca, Peter; Hasler, Pascal W; Barthelmes, Daniel; Arnold, Patrik; Matthias, Mooser; Scholl, Hendrik P N; Gerding, Heinrich; Garweg, Justus; Heeren, Tjebo; Balaskas, Konstantinos; de Carvalho, J Emanuel Ramos; Egan, Catherine; Tufail, Adnan; Zweifel, Sandrine A (2018). Safety and Feasibility of a Novel Sparse Optical Coherence Tomography Device for Patient-Delivered Retina Home Monitoring. Translational vision science & technology, 7(4), p. 8. Association for Research in Vision and Ophthalmology 10.1167/tvst.7.4.8
Translational Vision Science & Technology

Purpose To study a novel and fast optical coherence tomography (OCT) device for home-based monitoring in age-related macular degeneration (AMD) in a small sample yielding sparse OCT (spOCT) data and to compare the device to a commercially available r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb767b75d14f784bfa7c9f9d2de9ccd6
https://boris.unibe.ch/121827/1/i2164-2591-7-4-8.pdf

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High-Performance Virtual Reality Volume Rendering of Original Optical Coherence Tomography Point-Cloud Data Enhanced With Real-Time Ray Casting

Autor: Pascal W. Hasler, Lilian Witthauer, Adnan Tufail, Catherine A Egan, Konstantinos Balaskas, J. Emanuel Ramos de Carvalho, Faisal Mushtaq, Mark Mon-Williams, Philippe C. Cattin, Peter Maloca, Tjebo F. C. Heeren, Hendrik P. N. Scholl

Publikováno v: Translational Vision Science & Technology

Purpose: Feasibility testing of a novel volume renders technology to display optical coherence tomography data (OCT) in a virtual reality (VR) environment. Methods: A VR program was written in C++/OpenGL to import and display volumetric OCT data in r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f9f7d6acf03e78a187761ce67191a70
https://pubmed.ncbi.nlm.nih.gov/30002949

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3D printing of the choroidal vessels and tumours based on optical coherence tomography

Autor: Adnan Tufail, Pascal W. Hasler, Catherine A Egan, Peter Maloca, Richard F. Spaide, Simon P. Rothenbuehler, J. Emanuel Ramos de Carvalho

Publikováno v: Acta ophthalmologica. 97(2)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bbd1140a0da37c879a413066f7905ac
https://pubmed.ncbi.nlm.nih.gov/29240288

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Modulation of the Proteasome Pathway by Nano-Curcumin and Curcumin in Retinal Pigment Epithelial Cells

Autor: Cornelis J.F. Van Noorden, J. Emanuel Ramos de Carvalho, Ilse M. C. Vogels, Ingeborg Klaassen, Milan T. Verwoert, Reinier O. Schlingemann, Sabine Schipper-Krom, Eric Reits

Publikováno v: Ophthalmic research, 59(2), 98-109. S. Karger AG

Introduction: Curcumin has multiple biological effects including the modulation of protein homeostasis by the ubiquitin-proteasome system. The purpose of this study was to assess the in vitro cytotoxic and oxidative effects of nano-curcumin and stand

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf4aa41a052834749472262973cbba32
https://pubmed.ncbi.nlm.nih.gov/29073609

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Recent advances in ophthalmic molecular imaging

Autor: Frank D. Verbraak, Cornelis J.F. Van Noorden, Maurice C. G. Aalders, Reinier O. Schlingemann, J. Emanuel Ramos de Carvalho

Publikováno v: Survey of Ophthalmology, 59(4), 393-413. Elsevier USA

The aim of molecular imaging techniques is the visualization of molecular processes and functional changes in living animals and human patients before morphological changes occur at the cellular and tissue level. Ophthalmic molecular imaging is still

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd94062806f20a3cde565a1a3b7f0d95
https://pure.knaw.nl/portal/en/publications/52ca1424-a4e4-4ee9-a016-88dcb30f54c4

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COmplement factor 3a alters proteasome function in human RPE cells and in animal model of age-related RPE degeneration

Autor: Reinier O. Schlingemann, Theo G. M. F. Gorgels, Eric Reits, Sabine Schipper-Krom, Ilse M. C. Vogels, Arthur A.B. Bergen, J. Emanuel Ramos de Carvalho, Ingeborg Klaassen, Cornelis J.F. Van Noorden

Publikováno v: Investigative Ophthalmology & Visual Science, 54, 6489-6501. Association for Research in Vision and Ophthalmology Inc.
Investigative ophthalmology & visual science, 54(10), 6489-6501. Association for Research in Vision and Ophthalmology Inc.

PURPOSE: Complement activation plays an unequivocal role in the pathogenesis of age-related macular degeneration (AMD). More recent evidence suggests an additional role in AMD for the ubiquitin proteasome pathway (UPP), a protein-degradation nanomach

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::874fa67d83abdcf18b2d94e7c0a5f4ec
https://pure.knaw.nl/portal/en/publications/1336f8a4-d7e0-44ff-97bc-395df489bbd2

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