Zobrazeno 1 - 10
of 52
pro vyhledávání: '"J. Ellacott"'
Autor:
Ana M. Cruz, Katie M. Partridge, Yasaman Malekizadeh, Julia M. Vlachaki Walker, Paul G. Weightman Potter, Katherine R. Pye, Simon J. Shaw, Kate L. J. Ellacott, Craig Beall
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
AimWe evaluated the efficacy of a novel brain permeable “metformin-like” AMP-activated protein kinase activator, R481, in regulating glucose homeostasis.Materials and MethodsWe used glucose sensing hypothalamic GT1-7 neuronal cells and pancreatic
Externí odkaz:
https://doaj.org/article/f44879889ae04371b5abf856270d301a
Publikováno v:
Open Biology, Vol 11, Iss 10 (2021)
Time-restricted feeding (TRF) studies underscore that when food is consumed during the daily cycle is important for weight gain/loss because the circadian clock rhythmically modulates metabolism. However, the interpretation of previous TRF studies ha
Externí odkaz:
https://doaj.org/article/699f00646dd04b85a7882a48a7a5e7fb
Publikováno v:
Cells, Vol 11, Iss 21, p 3422 (2022)
Astrocytes contribute to glutamatergic signalling, which is required for hypoglycaemia counterregulation and is impaired by recurrent insulin-induced hypoglycaemia. This study examined the glutamate response of astrocytes when challenged with acute a
Externí odkaz:
https://doaj.org/article/29126711bddc4d2ab8c82c6d26c8075c
Autor:
Alastair J. MacDonald, Yu Hsuan Carol Yang, Ana Miguel Cruz, Craig Beall, Kate L. J. Ellacott
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Tight regulation of blood glucose is essential for long term health. Blood glucose levels are defended by the correct function of, and communication between, internal organs including the gastrointestinal tract, pancreas, liver, and brain. Critically
Externí odkaz:
https://doaj.org/article/696b633cbb13409dacc67f80725f02be
Recurrent hypoglycaemia, a common side-effect of insulin therapy in the treatment of type 1 diabetes, induces impaired glucose-sensing. Better understanding of how astrocytes, important non-neuronal cells in the brain, function in low glucose environ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41df3d216d81faf31ba8f87a74749ca4
Autor:
Fiona E. Holmes, Alastair J. MacDonald, Anthony E. Pickering, Kate L. J. Ellacott, Craig Beall
Publikováno v:
Glia
A role for glial cells in brain circuits controlling feeding has begun to be identified with hypothalamic astrocyte signaling implicated in regulating energy homeostasis. The nucleus of the solitary tract (NTS), within the brainstem dorsal vagal comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0b8659ae87136f36062af9c61e06ff0
https://doi.org/10.1002/glia.23774
https://doi.org/10.1002/glia.23774
The dorsal vagal complex (DVC) is a brainstem site regulating diverse aspects of physiology including food intake and blood glucose homeostasis. Astrocytes are purported to play an active role in regulating DVC function and, by extension, physiologic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a023531d04963f3cdc9a830b6acc4b96
https://doi.org/10.1101/2021.12.15.472746
https://doi.org/10.1101/2021.12.15.472746
Publikováno v:
Endocrine Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::344a5f606929af56810b013d43bc7aa5
https://doi.org/10.1530/endoabs.77.p182
https://doi.org/10.1530/endoabs.77.p182
Publikováno v:
Open Biology
Open Biology, Vol 11, Iss 10 (2021)
Open Biology, Vol 11, Iss 10 (2021)
Time-restricted feeding (TRF) studies underscore that when food is consumed during the daily cycle is important for weight gain/loss because the circadian clock rhythmically modulates metabolism. However, the interpretation of previous TRF studies ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3925b6ecb0fd7cf772b53cb76a806b26
http://europepmc.org/articles/PMC8492177
http://europepmc.org/articles/PMC8492177
Publikováno v:
Journal of neuroendocrinologyREFERENCES. 33(9)
Changes in mitochondrial function in a variety of cells/tissues are critical for orchestrating systemic energy homeostasis and are linked to the development of obesity and many of its comorbidities. The mitochondrial translocator protein of 18 kDa (T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55ab84fa8f3a90843604c3c1e255bf31
https://pubmed.ncbi.nlm.nih.gov/34423477
https://pubmed.ncbi.nlm.nih.gov/34423477