Zobrazeno 1 - 10
of 21
pro vyhledávání: '"J. E. Wellington"'
Publikováno v:
Virus Research. 79:125-135
Equine herpesvirus 1 glycoprotein D (EHV-1 gD) has been shown in mouse models and in the natural host to have potential as a subunit vaccine, using various expression systems that included Escherichia coli , baculovirus and plasmid DNA. With the aim
Publikováno v:
Archives of Virology. 145:2677-2686
The equine herpesvirus 1 (EHV-1) strain HVS25A regulatory genes IE and UL5, encoding homologues of herpes simplex virus 1 (HSV-1) ICP4 and ICP27 respectively, were cloned into a eukaryotic expression vector and the DNA injected intramuscularly into m
Publikováno v:
Archives of Virology. 145:2371-2385
Insertional mutagenesis was used to construct an equine herpesvirus 1 (EHV-1) mutant in which the open reading frame for glycoprotein D was replaced by a lacZ cassette. This gD deletion mutant (delta gD EHV-1) was unable to infect normally permissive
Publikováno v:
Veterinary Microbiology. 76:117-127
We have shown previously that equine herpesvirus 1 (EHV-1) glycoprotein D (gD) DNA elicited protective immune responses against EHV-1 challenge in murine respiratory and abortion models of EHV-1 disease. In this study, 20 horses, all with pre-existin
Publikováno v:
Veterinary Microbiology. 68:35-48
The potential of DNA-mediated immunisation to protect against equine herpesvirus 1 (EHV-1) disease was assessed in a murine model of EHV-1 respiratory infection. Intramuscular injection with DNA encoding the EHV-1 envelope glycoprotein D (gD) in a ma
Publikováno v:
Archives of Virology. 141:1785-1793
Equine herpesvirus 1 glycoprotein D (EHV-1 gD) expressed constitutively in mammalian cell lines had similar electrophoretic mobility to gD produced in EHV-1 infected cells but lacked a possibly complexed higher molecular weight form seen in the latte
Publikováno v:
Journal of General Virology. 77:75-82
Signal cleavage sites of equine herpesvirus 1 (EHV-1) glycoproteins D and B (gD and gB) and an endoproteolytic cleavage site of EHV-1 gB were determined by N-terminal amino acid sequencing and compared with known cleavage sites of homologues in other
Autor:
K. Sullivan, J. M. Whalley, James R. Gilkerson, D. Birch, J. E. Wellington, L. Seshadri, K. M. Ruitenberg, K. Hansen
Publikováno v:
Archives of virology. 152(4)
Equine herpesviruses 1 and 4 (EHV-1 and EHV-4) cause equine respiratory disease worldwide. However, only EHV-1 is a cause of abortion and neurological disease, despite the two viruses having all 76 genes in common. In addition EHV-1 has a broader hos
Publikováno v:
Veterinary immunology and immunopathology. 111(1-2)
A silent cycle of equine herpesvirus 1 infection was described following epidemiological studies of unvaccinated mares and foals on a Hunter Valley stud farm. Following the introduction of routine vaccination with an inactivated whole virus equine he
Publikováno v:
Veterinary immunology and immunopathology. 111(1-2)
We have previously demonstrated that intramuscular inoculation of EHV-1 glycoprotein D (gD) and glycoprotein B (gB) produced by a recombinant baculovirus and formulated with the adjuvant Iscomatrix™ elicited virus-neutralizing antibody and gD- and