Výsledky vyhledávání - "J. E. W. Lyall"

Adaptation of avian influenza virus to a swine host

Autor: J. E. W. Lyall, Sylvain Gandon, JinQi Fu, Angélique Teillaud, Simon D. W. Frost, Cathy Smith, Jean-Luc Guérin, Laurence Tiley, Sarah Leclaire, Vincent Bourret

Publikováno v: Virus Evolution
Virus Evolution, Oxford University Press, 2017, 3 (1), pp.vex007. ⟨10.1093/ve/vex007⟩
Virus evolution 1 (3), vex007. (2017)
Virus Evolution, 2017, 3 (1), pp.vex007. ⟨10.1093/ve/vex007⟩

International audience; The emergence of pathogenic RNA viruses into new hosts can have dramatic consequences for both livestock and public health. Here we characterize the viral genetic changes that were observed in a previous study which experiment

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc4098f2efc1ce5fa080739fc52eda6b
https://hal.inrae.fr/hal-02622007/document

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Asparagine 631 Variants of the Chicken Mx Protein Do Not Inhibit Influenza Virus Replication in Primary Chicken Embryo Fibroblasts or In Vitro Surrogate Assays

Autor: J. E. W. Lyall, Laurence Tiley, Georg Kochs, Camilla T. O. Benfield

Publikováno v: Journal of Virology. 82:7533-7539

Whether chicken Mx inhibits influenza virus replication is an important question with regard to strategies aimed at enhancing influenza resistance in domestic flocks. The Asn631 polymorphism of the chicken Mx protein found in the Shamo (SHK) chicken

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c51668789a1d0685936dfa4a8169c7d
https://doi.org/10.1128/jvi.00185-08

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Development of an improved polykaryon-based influenza virus rescue system

Autor: Mariette F. Ducatez, Vincent Bourret, Laurence Tiley, J. E. W. Lyall, Jean-Luc Guérin

Publikováno v: BMC Biotechnology, Vol 12, Iss 1, p 69 (2012)
BMC Biotechnology

Background Virus rescue from transfected cells is an extremely useful technique that allows defined viral clones to be engineered for the purpose of rational vaccine design or fundamental reverse genetics studies. However, it is often hindered by low

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e6e87bcc29a7b738ecbd77198aa5866
http://www.biomedcentral.com/1472-6750/12/69

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Suppression of avian influenza transmission in genetically modified chickens

Autor: J. E. W. Lyall, Laurence Tiley, Richard M. Irvine, Helen Sang, Alejandro Núñez, Auriol C. Purdie, Genevieve Rolleston-Smith, Adrian Sherman, Trevelyan J. McKinley, Ian H. Brown, Linzy Outtrim

Publikováno v: Science (New York, N.Y.). 331(6014)

Infection of chickens with avian influenza virus poses a global threat to both poultry production and human health that is not adequately controlled by vaccination or by biosecurity measures. A novel alternative strategy is to develop chickens that a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54ea18bd86e4c686dd8002b881ce3293
https://pubmed.ncbi.nlm.nih.gov/21233354

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The role and assembly mechanism of nucleoprotein in influenza A virus ribonucleoprotein complexes

Autor: Laurence Tiley, Lauren Turrell, J. E. W. Lyall, Ervin Fodor, Frank T. Vreede

Publikováno v: Nature communications

The nucleoprotein of negative-strand RNA viruses forms a major component of the ribonucleoprotein complex that is responsible for viral transcription and replication. However, the precise role of nucleoprotein in viral RNA transcription and replicati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91f77766f06fe59bdb5f2f5f089662e9
http://europepmc.org/articles/PMC4168216

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The Cytoplasmic Location of Chicken Mx Is Not the Determining Factor for Its Lack of Antiviral Activity

Autor: J. E. W. Lyall, Camilla T. O. Benfield, Laurence Tiley

Publikováno v: PLoS ONE, Vol 5, Iss 8, p e12151 (2010)
PLoS ONE

Background Chicken Mx belongs to the Mx family of interferon-induced dynamin-like GTPases, which in some species possess potent antiviral properties. Conflicting data exist for the antiviral capability of chicken Mx. Reports of anti-influenza activit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42c149baba61be17970f6f8e4f05fd18
https://doi.org/10.1371/journal.pone.0012151

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