Zobrazeno 1 - 10
of 128
pro vyhledávání: '"J. E. Rall"'
Publikováno v:
Mechanisms of Development. 123(9):689-701
Nuclear hormone receptors (NHRs) are important regulators of development and metabolism in animal species. They are characterized by the ability to regulate gene expression in response to the binding of small hydrophobic molecules, hormones, metaboli
Publikováno v:
Scopus-Elsevier
CHR3 is a Caenorhabditis elegans orphan nuclear hormone receptor highly homologous to Drosophila DHR3, an ecdysone-inducible gene product involved in metamorphosis. Related vertebrate factors include RORalpha/RZRalpha, RZRbeta and RevErb. Gel-shift s
Autor:
K, Simecková, E, Brozová, J, Vohánka, M, Pohludka, Z, Kostrouch, M W, Krause, J E, Rall, M, Kostrouchová
Publikováno v:
Folia biologica. 53(3)
The C. elegans genome encodes an unexpectedly large number of NHRs, the majority of which are classified as supplementary nuclear receptors (supnrs) that are likely to have evolved from an ancestral protein related to vertebrate HNF-4. To understand
Publikováno v:
Folia biologica. 52(4)
BIR-1 and Survivin are highly conserved members of the inhibitor of apoptosis protein family that regulate cell division in nematodes and mammals and inhibit apoptosis in mammals. In the C. elegans genome, bir-1 is organized in an operon together wit
Autor:
P, Libý, M, Kostrouchová, M, Pohludka, P, Yilma, P, Hrabal, J, Sikora, E, Brozová, J E, Rall, Z, Kostrouch
Publikováno v:
Folia biologica. 52(1-2)
Abnormal expression of histone deacetylases may contribute to the establishment of a cancer specific transcription profile. We examined expression of HDAC3 in human non-malignant gliosis and glial astrocytic tumours. Samples from four non-malignant g
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 100(9)
bir - 1 , a Caenorhabditis elegans inhibitor-of-apoptosis gene homologous to Survivin is organized in an operon with the transcription cofactor C. elegans SKIP ( skp - 1 ). Because genes arranged in operons are frequently linked functionally, we have
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 99(14)
SKI-binding protein (SKIP) is a transcription cofactor present in all eukaryotes. Here we show that SKIP is a unique protein that is required for Caenorhabditis elegans viability and development. Expression of CeSKIP (skp-1) assayed by RT-PCR and by
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 98(13)
CHR3 ( nhr-23 , NF1F4), the homologue of Drosophila DHR3 and mammalian ROR/RZR/RevErbA nuclear hormone receptors, is important for proper epidermal development and molting in the nematode Caenorhabditis elegans . Disruption of CHR3 ( nhr-23 ) functio
Autor:
J E Rall
Publikováno v:
The Journal of nervous and mental disease. 186(11)
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 95(23)
Nuclear hormone receptors comprise a characteristic family of transcription factors found in vertebrates, insects and nematodes. Here we show by cDNA and gene cloning that a Cnidarian, Tripedalia cystophora , possesses a retinoid receptor (jRXR) with