Zobrazeno 1 - 10
of 20
pro vyhledávání: '"J. E. Paulsen"'
Publikováno v:
The Journal of Peptide Research. 51:80-84
The function and proliferation of melanocyte cell populations are influenced by a wide range of hormones and growth factors. Local cell renewal after sudden melanocyte loss appears to be regulated according to a negative feedback principle, however.
Autor:
H. Enghardt-Barbieri, K. Trygg, N. Johansson, A. Widenfalk, J. E. Paulsen, Jan Alexander, Ann Thuvander, V. Bosnes, M. Olsen, K. Lund-Larsen, S. Jahrl, A. Vidnes, Karin Axberg, Karl Hult
Publikováno v:
Food and Chemical Toxicology. 39:1145-1151
Blood levels of ochratoxin A were determined in 406 Scandinavian blood donors (206 from Oslo, Norway, and 200 from Visby on the island of Gotland, Sweden), using an HPLC method. In connection with the blood collection, the subjects were asked to fill
Publikováno v:
Environmental Geology. 38:204-208
Bacterial interaction with oil and sea water, in a porous medium, was studied using a transparent micro model mounted on a cybernetic-controlled positioning board of an inverted microscope. This was interfaced with computer-operated image analysis an
Autor:
J E, Paulsen, J, Alexander
Publikováno v:
Anticancer research. 21(5)
We studied the effects of extra dietary methionine on the formation and growth of intestinal adenomas in the Min (Apc+/-) mouse, which is a murine model of the human familial adenomatous syndrome. The AIN-76A diet was supplemented with 0.7% L-methion
Publikováno v:
Cancer research. 61(24)
In our previous experiments, multiple injections with the food mutagen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) were used to induce intestinal tumors in C57BL/6J-multiple intestinal neoplasia (Min)/+ mice. To define the period of highes
Autor:
J E, Paulsen, K, Elgjo
Publikováno v:
In vivo (Athens, Greece). 15(5)
We have previously shown that the colon mitosis inhibitor (CMI) suppresses the growth of transplanted HT-29 human colon carcinoma cells by approximately 40%. However, this effect declined along the time-course, as the inoculums progressively grew lar
Publikováno v:
Cancer research. 61(13)
The multiple intestinal neoplasia (Min)/+ mouse, which harbors only one functional allele of the Apc gene, is susceptible to environmental factors that disrupt this gene and subsequently trigger Apc-driven tumorigenesis in the colon. Aberrant crypt f
Autor:
J E, Paulsen, C, Lützow-Holm
Publikováno v:
Anticancer research. 20(5B)
An important strategy in experimental chemotherapy of cancer is to combine agents with different mechanisms of action in order to achieve enhanced effect by synergism. We studied the combination of all-trans-retinoic acid (RA), difluoromethylornithin
Publikováno v:
Scandinavian journal of gastroenterology. 35(5)
Min mice are heterozygous for a nonsense mutation in the murine adenomatous polyposis coli (APC) gene and spontaneously develop multiple intestinal neoplasms similar to the familial adenomatous polyposis (FAP) syndrome in humans. Aberrant crypt foci
Publikováno v:
Pharmacologytoxicology. 85(2)
Epidemiological studies indicate an association between exposure to chlorinated drinking water and risk of intestinal cancer. In order to study this experimentally, we have examined the effects of 3,4-dichloro-5-hydroxy-2[5H]-furanone (mucochloric ac