Zobrazeno 1 - 10
of 30
pro vyhledávání: '"J. E. Ombetta"'
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 34:487-497
The radiolabelling of an iodinated analog of mazindol, 5-(4-[125I]-iodophenyl)-2,3-dihydro-5-hydroxy-5H-imidazo[2,1-a]isoindole, was performed in order to develop a potential tool for SPECT exploration of the presynaptic dopamine transporter in the h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e99f5e84f73d3c6e1190dd5eccb58a7
https://doi.org/10.1002/jlcr.2580340512
https://doi.org/10.1002/jlcr.2580340512
Publikováno v:
Spectrochimica Acta Part A: Molecular Spectroscopy. 49:1109-1119
Resume La condensation entre le mercaptoacetate d'ethyle et plusieurs 3-arylidenechroman-4-ones donne naissance aux 3-aryl-9 b -hydroxy-1,3,3 a ,9 b -tetrahydro-4 H -thieno[3,4- c ]benzo[ e ]pyrane-1-carboxylates d'ethyle correspondants. Malgre la pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b7ea6197dcdcfe5cbc846556f0d3474
https://doi.org/10.1016/0584-8539(93)80070-q
https://doi.org/10.1016/0584-8539(93)80070-q
Publikováno v:
ChemInform. 22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13df179c13d0775ebeabc5c9f36c4260
https://doi.org/10.1002/chin.199102208
https://doi.org/10.1002/chin.199102208
Publikováno v:
European Journal of Medicinal Chemistry. 25:629-632
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14cecfda384a34c3f35afd52e764b560
https://doi.org/10.1016/0223-5234(90)90189-a
https://doi.org/10.1016/0223-5234(90)90189-a
Autor:
Y. Frangin, E. Galinier, J. E. Ombetta, N. Rodier, J. M. Cense, Viatcheslav N. Agafonov, D. Guilloteau
Publikováno v:
Acta Crystallographica Section C Crystal Structure Communications. 49:841-843
5-(3-Iodophenyl)-2,3-dihydro-5H-imidazo[2,1-a]isoindol-5-ol. The pentagonal A and B rings show an envelope conformation and the hexagonal C and D rings are planar. The dihydroimidazoisoindole group is approximately planar and its least-squares plane
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2cb880d7abc7246b652ea9271121a982
https://doi.org/10.1107/s0108270192010540
https://doi.org/10.1107/s0108270192010540
Autor:
J. E. Ombetta, L. Pourcelot, Y. Frangin, Sylvie Bodard, H. Rafii, Denis Guilloteau, Jean-Claude Besnard, Sylvie Chalon
Publikováno v:
Life sciences. 58(14)
In vivo evaluation of MAO-A would be of great value for the diagnosis and follow-up of therapy of depression. In order to perform this exploration by SPECT, we developed an iodinated derivative of the reversible MAO-A inhibitor, moclobemide. Ro 11-99
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73bc0919f559e03f167f2ba53b347537
https://pubmed.ncbi.nlm.nih.gov/8614267
https://pubmed.ncbi.nlm.nih.gov/8614267
Autor:
Jean-Louis Baulieu, J. E. Ombetta, Isabelle Léna, Jean-Claude Besnard, Lucette Garreau, Anne-Marie Dognon, Sylvie Chalon, Denis Guilloteau, Y. Frangin
Publikováno v:
Nuclear medicine and biology. 22(6)
Monoamine oxidases are important in the regulation of monoaminergic neurotransmission. An increase in monoamine oxidase B (MAO B) has been observed in some neurodegenerative diseases, and therefore quantification of cerebral MAO B activity by SPECT w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7e7ff6d50a38014bf6a8e3f6ff81b12
https://pubmed.ncbi.nlm.nih.gov/8535333
https://pubmed.ncbi.nlm.nih.gov/8535333
Autor:
Hamid Rafii, Y. Frangin, Jean-Claude Besnard, Marie-Paule Vilar, J. E. Ombetta, Isabelle Léna, Sylvie Bodard, Anne-Marie Dognon, Sylvie Chalon, Lucette Garreau, Denis Guilloteau
Publikováno v:
Nuclear medicine and biology. 22(5)
We described the radiosynthesis of an analog of Ro 16-6491, [125I]N-(2-aminoethyl)-4-iodobenzamide, for SPECT exploration of the monoamine oxidase B (MAO-B) in human brain. The radiolabelling was carried out by nucleophilic exchange of the brominated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::462e763a3efcda75faa2aed3210189e6
https://pubmed.ncbi.nlm.nih.gov/7581172
https://pubmed.ncbi.nlm.nih.gov/7581172
Autor:
A. Djimde, N. Thelier, Y. Shi, C.-Z. Dong, L. Tsagris, F. Heymans, E. El-Hayek, S. Plocki, J.-E. Ombetta, F. Massicot, Caroline Chauvet, N. Gresh, François Rannou
Publikováno v:
Osteoarthritis and Cartilage. 18:S204
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bd18ba019290205d3b234105ade3b5e
https://doi.org/10.1016/s1063-4584(10)60481-5
https://doi.org/10.1016/s1063-4584(10)60481-5
Publikováno v:
Spectrochimica Acta Part A: Molecular Spectroscopy. 38:821-827
The spectroscopic properties (i.r., NMR) of 2-aryl-1,2-dihydro (4H) thieno[2,3-c]benzo[e]pyrane-4-ones have been studied. Chemical shifts and coupling constants of dihydrothienylic protons are affected by substitutions on the aryl ring and on homocyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8f5d3dc52fd0f61cd3b3a217c742de9
https://doi.org/10.1016/0584-8539(82)80101-3
https://doi.org/10.1016/0584-8539(82)80101-3