Zobrazeno 1 - 2
of 2
pro vyhledávání: '"J. E. Loeffert"'
Autor:
Robert S. B. Clark, Neal A. Seidberg, Kunlin Jin, Patrick M. Kochanek, Paula D. Nathaniel, Minzhi Chen, Simon C. Watkins, John A. Melick, Steven H. Graham, J. E. Loeffert, C. E. Dixon
Publikováno v:
Journal of Neurochemistry. 74:740-753
During programmed cell death, activation of caspase-3 leads to proteolysis of DNA repair proteins, cytoskeletal proteins, and the inhibitor of caspase-activated deoxyribonuclease, culminating in morphologic changes and DNA damage defining apoptosis.
Autor:
Donald W. Marion, Steven H. Graham, Robert B. Clark, Ronald L. Hamilton, Jun Chen, Patrick M. Kochanek, Simon C. Watkins, Minzhi Chen, J. E. Loeffert
Publikováno v:
ResearcherID
The bcl-2 and caspase families are important regulators of programmed cell death in experimental models of ischemic, excitotoxic, and traumatic brain injury. The Bcl-2 family members Bcl-2 and Bcl-xL suppress programmed cell death, whereas Bax promot