Extramedullary hematopoietic growth factor and cytokine gene expression indicate endocrine regulation of hematopoiesis in patients with acute appendicitis

Autor: W. F. J. Veenhof, F. H. M. Cluitmans, R. Willemze, J. E. Landegent, J.H.F. Falkenburg, B. H. J. Esendam

Publikováno v: Annals of Hematology. 75:201-205

To analyze the role of hematopoietic growth factors (HGFs) and other cytokines in the regulation of hematopoiesis in vivo, we investigated HGFs and cytokine gene expression in appendices obtained from patients who underwent surgery for suspected appe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::717442405778486531e67f42a80742af
https://doi.org/10.1007/s002770050343

Haemopoietic growth factor tyrosine kinase receptor expression profiles in normal haemopoiesis

Autor: J. E. Landegent, Monique Visser, Roel Willemze, Renate D. Sonneveld

Publikováno v: British Journal of Haematology. 94:236-241

Expression profiles were generated for the haemopoietic tyrosine kinase receptors (HGF-TKRs or class III TKRs) by PCR on cDNA samples (RT-PCR) using a degenerate primer set. Each profile consisted of primary and secondary, i.e. enriched for less-expr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::663bd630859faa05460fe7d648d09f73
https://doi.org/10.1046/j.1365-2141.1996.d01-1789.x

In vitro-induced resistance to the deoxycytidine analogues cytarabine (AraC) and 5-aza-2′-deoxycytidine (DAC) in a rat model for acute myeloid leukemia is mediated by mutations in the deoxycytidine kinase (dck) gene

Autor: R. Willemze, M. W. Honders, A. P. A. Stegmann, J. E. Landegent, A. Hagemeijer, B. Hoebee

Publikováno v: Annals of Hematology. 71:41-47

The deoxycytidine kinase (dck) gene encodes the enzyme responsible for the metabolic activation of the antileukemic drugs cytosine arabinoside (AraC) and 5-aza-2'-deoxycytidine (decitabine, DAC). The dck locus was analyzed at the chromosomal and the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b1fd927693f4b0f08140fe9653638c0
https://doi.org/10.1007/bf01696231

Abstracts of oral presentations

Autor: R. Boulieu, A. Lenoir, J. F. Mornex, C. Bohman, J. Balzarini, P. Wigerinck, A. Aerschot, P. Herdewijn, Erik Clercq, S. Brosh, E. Zoref-Shani, O. Sperling, E. Danziger, Y. Sidi, Y. Bromberg, Renate Burgemeister, Elke Rötzer, Wolf Gutensohn, G. P. Connolly, P. J. Harrison, R. B. Diasio, Z. Lu, R. Zhang, U. Gresser, W. Gutensohn, R. Resta, L. F. Thompson, F. Javaux, M. F. Vincent, G. Berghe, I. Kamilli, R. Rauch, D. Hahn, C. W. Keuzenkamp-Jansen, R. A. Abreu, J. P. M. Bökkerink, M. A. H. Heijden, M. Löffler, C. Becker, E. Wegerie, M. Marcussen, K. Overgaard-Hansen, H. Klenow, A. M. Marinaki, E. H. Harley, M. B. McBride, H. A. Simmonds, F. Moro, J. S. Cameron, C. S. Ogg, D. G. Williams, S. Rigden, G. Haycock, M. E. Miranda, J. G. Puig, F. A. Mateos, J. O. Vázquez, V. W. T. Ruiz Haperen, G. Veerman, J. B. Vermorken, G. J. Peters, C. L. Wilt, P. Noordhuis, K. Smid, H. M. Pinedo, C. Salerno, A. Lomonte, O. Giardini, C. Crifo, R. T. Smolenski, M. H. Yacoub, A. M. -L. Seymour, A. P. A. Stegmann, M. W. Honders, R. Willemze, J. E. Landegent, E. H. Stet, G. M. Vogels-Mentink, L. H. J. Lambooy, J. M. F. Trijbels, R. J. Torres, M. G. Tozzi, R. Pesi, M. Turriani, S. Allegrini, M. Camici, P. L. Ipata, A. A. Berg, J. R. Meinsma, H. Lenthe, A. H. Gennip, A. B. P. Kuilenburg, N. G. G. M. Abeling, H. D. Bakker, R. J. Slingerland, F. Bergh, R. L. Sabina

Publikováno v: Pharmacy World & Science. 15:F7-F14

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::998f79b3fc5c41061e4d3e16542225b7
https://doi.org/10.1007/bf02297670

Clonal involvement of granulocytes and monocytes, but not of T and B lymphocytes and natural killer cells in patients with myelodysplasia: analysis by X-linked restriction fragment length polymorphisms and polymerase chain reaction of the phosphoglycerate kinase gene

Autor: Willem E. Fibbe, E. De Graaff, H. Van Kamp, R. P. M. Jansen, J. E. Landegent, M. Van Der Keur, Roelof Willemze

Publikováno v: Blood. 80:1774-1780

To determine the clonal nature of hematopoiesis and to assess lineage involvement in patients with myelodysplastic syndromes (MDS), we used restriction fragment length polymorphisms of the X-linked genes phosphoglycerate kinase (PGK1) and hypoxanthin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1712c010efc1dda0148bc8e40a1daf78
https://doi.org/10.1182/blood.v80.7.1774.1774