Abstract 262: Gene Expression Profiling of Hypertrophic and Failing Cardiomyocytes Identifies New Players Involved in Heart Failure

Autor: Folkert W. Asselbergs, J. E. C. Eding, Aryan Vink, Danielle Versteeg, Monika M Gladka, Marta Vigil-Garcia, Alex Bossu, Charlotte Demkes, Eva van Rooij, Magdalena Harakalova, Hesther de Ruiter, Toon A.B. van Veen

Publikováno v: Circulation Research. 125

Pathological remodeling during cardiac disease is a detrimental response characterized by cardiomyocyte hypertrophy and fibroblast activation, which can ultimately lead to heart failure. Genome wide expression analysis on full heart tissue have been

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d63bc19db88c27d83a1d5fd94b0cd866
https://doi.org/10.1161/res.125.suppl_1.262

Abstract 786: A Novel Desmoplakin Mutation Contributes to Arrhythmogenic Cardiomyopathy

Autor: Sebastiaan J. van Kampen, J. E. C. Eding, Toon A.B. van Veen, Teun P. de Boer, Eva van Rooij, Eirini Kyriakopoulou, Su Ji Han, Birgit Goversen, Jantine Monshouwer-Kloots

Publikováno v: Circulation Research. 125

Genetic alterations in desmosomal genes are associated with arrhythmogenic cardiomyopathy (ACM). This condition is characterized by sudden cardiac death, severe arrhythmias, and the presence of fibro-fatty patches within the myocardium. Despite the f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4c58d1b689a24de079850d1374cd287f
https://doi.org/10.1161/res.125.suppl_1.786

A systematic review of computed tomography detection of cartilage invasion in laryngeal carcinoma

Autor: Inge Wegner, Francien E. Flokstra, Babette D. M. Diemel, Wilko Grolman, Anda P. J. Adolphs, Weibel W. Braunius, Nienke A. Boersma, J. E. C. Eding

Publikováno v: The Laryngoscope. 125:1650-1655

OBJECTIVES/HYPOTHESIS: This systematic review aimed to assess the diagnostic value of computed tomography (CT) in detecting cartilage invasion among patients with laryngeal carcinoma. DATA SOURCES: PubMed, Embase, and the Cochrane Library. REVIEW MET

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6f10fb022249765ce3276e2213c0fc4f
https://doi.org/10.1002/lary.25145

The Efficacy of Cardiac Anti-miR-208a Therapy Is Stress Dependent

Autor: Anita G. Seto, Marc Isabelle, Charlotte J. Demkes, Stefano Chimenti, Aimee L. Jackson, Joshua M. Lynch, Hillary M. Semus, Rusty L. Montgomery, J. E. C. Eding, Eva van Rooij

Publikováno v: Molecular Therapy
Molecular Therapy, 25(3), 694-704. Nature Publishing Group
Molecular Therapy, 25(3), 694. Nature Publishing Group

MicroRNAs (miRNAs) are important regulators of biology and disease. Recent animal efficacy studies validate the therapeutic benefit of miRNA modulation and underscore the therapeutic value of miRNA-targeting oligonucleotides. However, whether disease

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c7fbcd689632b99e3ab061c49479222
https://pubmed.ncbi.nlm.nih.gov/28202391

Similar effect of autologous and allogeneic cell therapy for ischemic heart disease: results from a meta-analysis of large animal studies

Autor: S. J. Jansen Of Lorkeers, J. E. C. Eding, T. I. G. Van Der Spoel, H. M. Vesterinen, S. Koudstaal, E. S. Sena, P. A. Doevendans, M. R. Macleod, S. A. J. Chamuleau

Publikováno v: European Heart Journal. 34:P1462-P1462

Introduction: In regenerative therapy for ischemic heart disease use of both autologous and allogeneic stem cells have been investigated. An important drawback of autologous cell therapy is the restricted availability, especially in the acute setting

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3aeb4f787e5f5fa8cf8ae3d661efc899
https://doi.org/10.1093/eurheartj/eht308.p1462