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Effects of plasma kallikrein deficiency on haemostasis and thrombosis in mice: Murine Ortholog of the Fletcher Trait

Autor: P. L. Smith, J.-P. Revelli, William A. Schumacher, F. Barbera, J. E. Bird, Xinkang Wang, Dietmar A. Seiffert

Publikováno v: Thrombosis and Haemostasis. 107:1141-1150

SummaryPlasma kallikrein is a multifunctional serine protease involved in contact activation of coagulation. Deficiency in humans is characterised by prolonged activated partial thromboplastin time (aPTT); however, the balance between thrombosis and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b31925308292bfcb8bf173f950292b2e
https://doi.org/10.1160/th11-10-0682

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Captopril prevents nephropathy in HIV-transgenic mice

Autor: S K Durham, P H Gitlitz, D M Dambach, J E Bird, M R Giancarli, J B Kopp, M M Mozes, D G Pandya

Publikováno v: Scopus-Elsevier

Transgenic mice (T26) bearing the envelope, regulatory, and accessory genes of HIV- I develop renal disease resembling human HIV-associated nephropathy (HIVAN). Effects of vehicle (VEH) and the angiotensin-converting enzyme inhibitor captopril (CAP)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a108e8f0e45556f2e084f940695d1db7
https://doi.org/10.1681/asn.v981441

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Cardiovascular and Renal Effects of Endothelin B Receptor Selective Agonists in Spontaneously Hypertensive Rats

Autor: Giancarli Mr, J. E. Bird

Publikováno v: Journal of Cardiovascular Pharmacology. 28:381-384

Renal effects of endothelin (ET)-3 have been described in normotensive but not spontaneously hypertensive rats (SHR). Infusion (170 ng/kg/min) of the ETB receptor selective agonists ET-3 and sarafotoxin S6c (SS6c) was used to investigate ETB receptor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a255c6843b9d8c99e385f6c7ddb2589
https://doi.org/10.1097/00005344-199609000-00006

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A role for endothelin ETa receptors in regulation of renal function in spontaneously hypertensive rats

Autor: Maria L. Webb, M. M. Asaad, Chia-Ching Chao, J. E. Bird, Mary Giancarli, Charles R. Dorso

Publikováno v: European Journal of Pharmacology. 294:183-189

While there is evidence to suggest that endothelin-1 is involved in regulation of kidney function and blood pressure, the importance of endothelin ETA receptors in this area has not been clearly defined. The novel, non-peptide endothelin ETA receptor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea3f4d3f819de732422f69d8a37b6cb1
https://doi.org/10.1016/0014-2999(95)00537-4

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Endogenous Synthesis of Endothelin-1 May Mediate a Delayed Pressor Response After Injection of Endothelin-1 in Rats

Autor: J. E. Bird, Waldron Tl

Publikováno v: Journal of Cardiovascular Pharmacology. 25:307-313

We previously described delayed pressor response (DPR) 3 h after endothelin (ET)-1 injection in normotensive rats. In the current study, we examined effects of the ETA receptor antagonist BQ123 (0.01 mumol/kg/min intravenously, i.v.), phosphoramidon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60446b7145683b09cae935ae54cafe23
https://doi.org/10.1097/00005344-199502000-00017

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Effects of the Endothelin (ET) Receptor Antagonist BQ 123 on Initial and Delayed Vascular Responses Induced by ET-1 in Conscious, Normotensive Rats

Autor: Charles R. Dorso, M. M. Asaad, J. E. Bird, Waldron Tl

Publikováno v: Journal of Cardiovascular Pharmacology. 22:69-73

The ETA receptor antagonist, BQ 123 was used to characterize depressor and initial and delayed pressor responses to ET-1 in conscious rats. BQ 123 (0.001-0.01 mumol/kg/min) dose-dependently inhibited the initial ET-1 (0.1 nmol/kg) pressor response, r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::366dcda5c6159ae92e44f988842e153e
https://doi.org/10.1097/00005344-199307000-00012

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