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pro vyhledávání: '"J. Douglas Brailsford"'
Publikováno v:
Journal of Theoretical Biology. 60:131-145
Mathematical modeling was used to test two assumptions regarding red cell shape. The assumptions are that the elastic moduli of the red cell membrane are uniformly distributed throughout the membrane shell and that the biconcave shape results primari
Publikováno v:
Journal of Theoretical Biology. 86:513-529
Crenation can be thought of as a surface instability caused by intrinsic precurvature of the membrane. Mathematical modeling, on the presupposition that the red blood cell is a thin shell consisting of a connected (coupled) bilayer having uniformly d
Publikováno v:
Anesthesiology. 57:399-403
The extent to which semiturgid red cells could enter the tip of a glass micropipette of approximately 1-microgram internal diameter was used to measure the area expansion of freshly drawn erythrocytes. The pipette was mounted in a gas-tight glass obs
Publikováno v:
Journal of Theoretical Biology. 140:185-192
A physical macromodel of the erythrocyte membrane was constructed to investigate the effect of intrinsic membrane precurvature on a unique non-isotropic, composite material that dissipated shear energy but stored bending energy. The intrinsic precurv
Autor:
J. Douglas Brailsford, Brian S. Bull
Publikováno v:
Blood. 40:550-559
The zeta sedimentation ratio (ZSR) is a measurement similar to the determination of the erythrocyte sedimentation rate (ESR) but possesses sevaral advantages. It is unaffected by anemia and responds in a linear manner to increase in fibrinogen and/or
Autor:
J. Douglas Brailsford, Brian S. Bull
Publikováno v:
Blood. 41:833-844
New evidence is presented to show that the dimple and the annulus of the red cell are not restricted to specific locations on the membrane. This eliminates all but one of the current theories of biconcavity and supports the view that the membrane has
Publikováno v:
Red Cell Rheology ISBN: 9783540090014
A recently published mathematical analysis allows the precise determination of the forces which acting on the red cell membrane cause any red cell to assume a particular shape. The effective use of this analysis in the study of membrane physiology an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e5f0bbe95d7a0fe27582f763f05f0ca
https://doi.org/10.1007/978-3-642-67059-6_24
https://doi.org/10.1007/978-3-642-67059-6_24
Publikováno v:
Red Cell Rheology ISBN: 9783540090014
The aspiration of red cell membrane into small holes is a technique that has been widely used to measure membrane elastic moduli.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37548ecdf24595f36e9f94eb180b20a4
https://doi.org/10.1007/978-3-642-67059-6_2
https://doi.org/10.1007/978-3-642-67059-6_2
Publikováno v:
Red Cell Rheology ISBN: 9783540090014
Two techniques for measuring the deformability of the red blood cell membrane give divergent results. The folded cell traction technique indicates that an exponential stiffening occurs with increasing deformation, a response highly characteristic of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb145c844bc0380e59961b0a65b44623
https://doi.org/10.1007/978-3-642-67059-6_3
https://doi.org/10.1007/978-3-642-67059-6_3
Autor:
Brian S. Bull, J. Douglas Brailsford
Publikováno v:
Journal of theoretical biology. 39(2)
Dimensionally accurate transformation from sphere to biconcave disc and back to sphere is demonstrated in a dry macromodel of the red cell. A correct hypothesis of the membrane ultrastructure must accommodate the minimum mechanical requisites of the