Zobrazeno 1 - 10
of 204
pro vyhledávání: '"J. Donald Capra"'
Publikováno v:
Clinical and Developmental Immunology, Vol 2013 (2013)
Externí odkaz:
https://doaj.org/article/9e786b20a603417fa360c869c1a1f4f1
Autor:
Petra Kaufmann, Brian Dickie, Lucie Bruijn, David A. Chad, J. Donald Capra, Sanjay I. Bidichandani, John Ferguson, Melissa Forsythe, Annette Kirshner, William Monti, Denise Figlewicz
Publikováno v:
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. 14:62-66
Ten groups presented their perspectives on facilitating clinical research in ALS including four federal agencies, four disease organizations, one foundation and one advocacy group. The federal agencies (National Institute of Neurological Disorders an
Autor:
Robert C. Giles, J. Donald Capra
Publikováno v:
Tissue Antigens. 25:57-68
Publikováno v:
Journal of Biological Chemistry. 281:12370-12380
Antibody and T cell receptor genes are assembled from gene segments by V(D)J recombination to produce an almost infinitely diverse repertoire of antigen specificities. Recombination is initiated by cleavage of conserved recombination signal sequences
Publikováno v:
Blood. 104:2981-2987
Several characteristics of the immunoglobulin (Ig) repertoire in fetuses and adults set them apart from each other. Functionally, this translates into differences in the affinity and effectiveness of the humoral immune response between adults and the
Autor:
J. Donald Capra, Angela Boston, Kenneth Wilson, Grant R. Kolar, Patrick C. Wilson, Yong-Jun Liu, Nai-Ying Zheng, Virginia Pascual, Xiaojian Wang, Stephen M. Jackson
Publikováno v:
Journal of Clinical Investigation. 113:1188-1201
Current paradigms of peripheral B cell selection suggest that autoreactive B cells are controlled by clonal deletion, anergy, and developmental arrest. We report that changes to the human antibody repertoire likely resulting from these mechanisms bot
Autor:
J. Donald Capra, Kendra D. White
Publikováno v:
The Journal of Experimental Medicine
Polymeric immunoglobulins provide first line humoral defense at mucosal surfaces to which they are specifically transported by the polymeric immunoglobulin receptor (pIgR) on mucosal and glandular epithelial cells. Previous studies from our laborator
Autor:
J. Donald Capra, Michael Fougereau
Publikováno v:
Immunology today. 4(7)
Idiotypes on immunoglobulin molecules have been used for years as serological markers of variable regions but nearly two decades after their discovery, precise structural correlates for these antigenic determinants are still exceedingly difficult to
Publikováno v:
Immunology today. 7(2)
The V-D junctional residue at position 99 of AIJ anti-arsonate antibodies with a major cross-reactive idiotype is invariably a serine. This serine is not encoded in the germline of either the VH or DH gene segments nor can it be generated by intracod