Zobrazeno 1 - 10
of 135
pro vyhledávání: '"J. Diliberto"'
Publikováno v:
Toxicological Sciences. 164:218-228
The effects of body fat mass on the elimination of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) was examined in mice. When male C57BL/6J mice are fed a high-fat, simple carbohydrate diet (HFD) for 13 weeks, they develop an obese phenotype. In contrast,
Publikováno v:
Journal of Endodontics. 43:2014-2019
Introduction No research exists evaluating the influences of specific variables such as obturation length, radiodensity, or the presence of voids on interpretation of periradicular area. The purpose of this study was to evaluate the effects of obtura
Autor:
William P. Hanafin, Paul J. A. Kenis, Nagendraprabhu Ponnuraj, Stephen J. DiLiberto, H. Rex Gaskins, Vladimir L. Kolossov, Jessica N. Beaudoin
Publikováno v:
American Journal of Physiology-Cell Physiology. 309:C81-C91
Excessive oxidation is widely accepted as a precursor to deleterious cellular function. On the other hand, an awareness of the role of reductive stress as a similar pathological insult is emerging. Here we report early dynamic changes in compartmenta
Autor:
David M. DeMarini, Janet J. Diliberto, Larry D. Claxton, Daniel H. Kusnierz, Valerie Marshall, Adam Swank, Sarah H. Warren, Thomas J. Hughes
Publikováno v:
Chemosphere. 120:690-696
U.S. Environmental Protection Agency (US EPA) Regional Applied Research Effort (RARE) projects address the effects of environmental pollutants in a particular region on the health of the population in that region. This report is part of a RARE projec
Autor:
William P. Hanafin, Denisa E. Bica, Vladimir L. Kolossov, Jessica N. Beaudoin, H. Rex Gaskins, Paul J. A. Kenis, Stephen J. DiLiberto
Publikováno v:
Experimental Biology and Medicine. 239:394-403
The glutathione couple GSH/GSSG is the most abundant cellular redox buffer and is not at equilibrium among intracellular compartments. Perturbation of glutathione poise has been associated with tumorigenesis; however, due to analytical limitations, t
Autor:
Jessica N. Beaudoin, Stephen J. DiLiberto, William P. Hanafin, Vladimir L. Kolossov, H. Rex Gaskins, Paul J. A. Kenis
Publikováno v:
Biochemical and Biophysical Research Communications. 439:517-521
We have implemented a ratiometric, genetically encoded redox-sensitive green fluorescent protein fused to human glutaredoxin (Grx1-roGFP2) to monitor real time intracellular glutathione redox potentials of mammalian cells. This probe enabled detectio
Publikováno v:
Environmental Science & Technology. 46:13494-13503
The metabolism of α- and γ-hexabromocyclododecane (HBCD) was investigated in adult C57BL/6 female mice. α- or γ-[(14)C]HBCD (3 mg/kg bw) was orally administered with subsequent urine and feces collection for 4 consecutive days; a separate group o
Publikováno v:
Toxicological Sciences. 123:256-263
Hexabromocyclododecane (HBCD) is a mixture of three stereoisomers alpha (α), beta (β), and gamma (γ). γ-HBCD dominates the mixture (∼70%), and despite α-HBCD's minor contribution to global HBCD production and usage (∼10%), it is the dominant
Publikováno v:
Toxicological Sciences. 121:234-244
Alpha-hexabromocyclododecane (α-HBCD) is an emerging persistent organic pollutant present in the hexabromocyclododecane (HBCD) commercial mixture. HBCD is used as an additive flame retardant in a wide variety of household consumer products. Three ma
Autor:
David T. Szabo, Vicki M. Richardson, Linda S. Birnbaum, David G. Ross, Prasada Rao S. Kodavanti, Janet J. Diliberto
Publikováno v:
Toxicological Sciences. 107:27-39
Previous studies demonstrated that perinatal exposure to polybrominated diphenyl ethers (PBDEs), a major class of brominated flame retardants, may affect thyroid hormone (TH) concentrations by inducing hepatic uridinediphosphate-glucoronosyltransfera