Genetic analysis of the Drosophila ESCRT-III complex protein, VPS24, reveals a novel function in lysosome homeostasis.

Autor: Jonathan R Florian, Samuel J DeMatte, Devon M Sweeder, Richard W Ordway, Fumiko Kawasaki

Publikováno v: PLoS ONE, Vol 16, Iss 5, p e0251184 (2021)

The ESCRT pathway is evolutionarily conserved across eukaryotes and plays key roles in a variety of membrane remodeling processes. A new Drosophila mutant recovered in our forward genetic screens for synaptic transmission mutants mapped to the vps24

Externí odkaz: https://doaj.org/article/d82a566b20c540c8b49bc3694483e809

Progression of Interstitial Lung Disease in Systemic Sclerosis: The Importance of Pneumoproteins Krebs von den Lungen 6 and CCL18

Autor: Elizabeth R. Volkmann, Donald P. Tashkin, Masataka Kuwana, Ning Li, Michael D. Roth, Julio Charles, Faye N. Hant, Galina S. Bogatkevich, Tanjina Akter, Grace Kim, Jonathan Goldin, Dinesh Khanna, Philip J. Clements, Daniel E. Furst, Robert M. Elashoff, Richard M. Silver, Shervin Assassi, A. C. Theodore, R. W. Simms, E. Kissin, F. Y. Cheong, V. D. Steen, C. A. Read, C. Fridley, M. Zulmatashvili, R. A. Wise, F. M. Wigley, L. Hummers, G. Leatherman, R. M. Silver, C. Strange, F. N. Hant, J. Ham, K. Gibson, D. Rosson, D. P. Tashkin, R. M. Elashoff, M. D. Roth, P. J. Clements, D. Furst, E. R. Volkmann, S. Kafaja, E. Kleerup, D. Elashoff, J. Goldin, E. Ariola, G. Marlis, J. Mason‐Berry, P. Saffold, M. Rodriguez, L. Guzman, J. Brook, J. Golden, M. K. Connolly, A. Eller, D. Leong, M. Lalosh, J. Obata, S. Volkov, D. Schraufnagel, S. Arami, D. Franklin, J. Varga, J. Dematte, M. Hinchcliff, C. DeLuca, H. Donnelly, C. Marlin, D. J. Riley, V. M. Hsu, D. A. McCloskey, K. Phillips, D. Khanna, F. J. Martinez, E. Schiopu, J. Konkle, M. Mayes, B. Patel, S. Assassi, F. Tan, A. Fischer, J. Swigris, R. Meehan, K. Brown, T. Warren, M. Morrison, M. B. Scholand, T. Frecht, P. Carey, M. Villegas, J. Molitor, P. Carlson

Publikováno v: Arthritis Rheumatol

OBJECTIVE To investigate the relationship between Krebs von den Lungen 6 (KL-6) and CCL18 levels and the severity and progression of systemic sclerosis (SSc)-related interstitial lung disease (ILD). METHODS Patients enrolled in the Scleroderma Lung S

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b316810eb4494f3ff743a8c51f40329
https://doi.org/10.1002/art.41020

Nintedanib in patients with progressive fibrosing interstitial lung diseases-subgroup analyses by interstitial lung disease diagnosis in the INBUILD trial: a randomised, double-blind, placebo-controlled, parallel-group trial

Autor: Rainer Georg Goeldner, S. Abe, Dirk Skowasch, Romain Kessler, S. Izumi, A. Barczyk, E. Belloli, J. S. Park, H. Takaya, C. Marquette, Neil Ettinger, Krishna Thavarajah, Nina Patel, Manuel Quaresma, Yasuhiko Nishioka, D Koschel, Silvia Quadrelli, M. A. Bergna, J. Sauleda, M. Salinas Fénero, J. Kang, G. Giessel, Oksana A. Shlobin, Kevin K. Brown, T. Kawamura, Ketan P. Buch, W. Randerath, O. Acosta, A. Silva Orellana, L. Wemeau, N. Sakamoto, Bruno Crestani, Sonye K. Danoff, Shane Shapera, S. Stieglitz, M. Reynaud-Gaubert, Tejaswini Kulkarni, P. Elias, Leslie Tolle, Lake Morrison, C. Glazer, Yoshikazu Inoue, Rozsa Schlenker-Herceg, Yolanda Mageto, Anand Devaraj, Zeenat Safdar, H. Hayashi, Y. Kim, Nik Hirani, Srihari Veeraraghavan, Sylvain Marchand-Adam, S. Cerri, J. Golden, D. Hotchkin, Rebecca Bascom, K. Ichikado, Martin Kolb, Nazia Chaudhuri, H. Cai, B. Crestani, J. W. Song, V. Yakusevich, Anoop M. Nambiar, Sergey Moiseev, Y. Kondoh, F. Lebargy, Wim A. Wuyts, Maria Padilla, A. Gamez-Dubuis, Sergey Avdeev, A. León Jiménez, R. Martinez, Luca Richeldi, J. Dematte D'Amico, Teng Moua, E. Bergot, J. Falk, Benjamin Bondue, K. Kishi, Danielle Antin-Ozerkis, L. Gómez Carrera, Francesco Bonella, Vincent Cottin, T. Moua, A. Villar, Stéphane Jouneau, Z. Xu, R. Hallowell, Mary E. Strek, H. Takahashi, Antje Prasse, A. Cantin, M. Okamoto, G. Criner, M. Rossman, M. Schwartz, R. Refini, Myriam Aburto, S. Makino, Y. Inoue, L. Jones, J. Burk, L. Morrow, Shelley L. Schmidt, S. Chaaban, M. Ilkovich, J. A. Rodríguez Portal, Athol U. Wells, S. Blaas, C. Andrews, D. M. Castillo Villegas, Caroline Dahlqvist, Q. Luo, H. Yamauchi, Justin M. Oldham, Julien Guiot, M. Kolb, Nitin Y. Bhatt, Y. Yamada, Maria Otaola, Alberto Pesci, E. Britt, W. Wuyts, E. Jassem, Daniel F. Dilling, Kevin R. Flaherty, H. Kitamura, H. Poonyagariyagorn, Y. Miyazaki, Robert J. Kaner, L. Pitts, Toby M. Maher, Marilyn K. Glassberg, G. Arce, J. Kus, S. Weigt, E. R. Fernández Pérez, Ivan O. Rosas, Michael Kreuter, Claudia Valenzuela, S. Tomassetti, Susanne Stowasser, K. Tomii, C. Kono, Ben Hope-Gill, D. Ziora, B. Sigal, E. Bazdyrev, R. Maturana Rozas, Paul Beirne, T. Saito, F. Varone, T. Suda, M. Arias, A. Cazaux, J. Hetzel, Helen Stone, Maria Molina-Molina, F. Riviere, L. Homik, Mary Beth Scholand, A. Gifford, W. Piotrowski, Carlo Vancheri, T. Takeuchi, H. Sugiura, M. Martínez, Hilario Nunes

Publikováno v: The Lancet. Respiratory medicine, 8 (5

The INBUILD trial investigated the efficacy and safety of nintedanib versus placebo in patients with progressive fibrosing interstitial lung diseases (ILDs) other than idiopathic pulmonary fibrosis (IPF). We aimed to establish the effects of nintedan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12fb103566afe883ea90e5352d7b9ae8
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/305426

Evidence of Airflow Obstruction in Systemic Sclerosis

Autor: Monique Hinchcliff, J Dematte D'Amico, John Varga, S Patel, Krishna Thavarajah

Publikováno v: C45. ILD AND CONNECTIVE TISSUE DISORDERS II.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::748bb2eead1200860fa0b34848307a69
https://doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a4495

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