Zobrazeno 1 - 10
of 47
pro vyhledávání: '"J. Dellwo"'
Autor:
Hugo Ceulemans, Martin J Dellwo, Renee L. DesJarlais, Ann Vos, Kiran Kumar, Keith McCormick, Denise Morrison, Dmitrii Rassokhin, Vladimir Chupakhin, Eric Paternoster
Publikováno v:
Future medicinal chemistry. 13(19)
Background: Accurate prediction of absorption, distribution, metabolism and excretion (ADME) properties can facilitate the identification of promising drug candidates. Methodology & Results: The authors present the Janssen generic Target Product Prof
Autor:
M. Walid Qoronfleh, D. M. Schneider, Karen J. Vavra, Richard B. Ciccarelli, Joseph Falvo, Ewell R. Cook, Alan M. Mathiowetz, Haiyan Wang, Robert C. Wahl, Martin J. Dellwo, Mark A. McCoy, T. M. Banks, Tricia A. Pulvino
Publikováno v:
Journal of Biomolecular NMR. 9:11-24
We report here the backbone 1HN, 15N, 13Cα, 13CO, and 1Hα NMR assignmentsfor the catalytic domain of human fibroblast collagenase (HFC). Three independentassignment pathways (matching 1H, 13Cα, and 13CO resonances) were used to establishsequential
Autor:
G.D. Alton, J. Dellwo
Publikováno v:
Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. 382:225-231
Among several major challenges posed by generating and accelerating adequate intensities of RIBs, selection of the most appropriate target material is perhaps the most difficult because of the requisite fast and selective thermal release of minute am
Publikováno v:
Physical Review A. 50:3861-3864
The cross section for single-photon detachment of an electron from the metastable ${\mathrm{Be}}^{\mathrm{\ensuremath{-}}}$ ion has been measured at a photon energy of 2.076 eV to be 31\ifmmode\pm\else\textpm\fi{}3 Mb. The method of laser photodetach
Publikováno v:
Review of Scientific Instruments. 65:2006-2011
A versatile, high‐intensity, negative ion source has been designed and is now under construction which can be operated in either the cesium‐sputter or plasma‐sputter mode. The cesium‐sputter mode can be effected by installation of a newly des
Publikováno v:
Journal of Physics B: Atomic, Molecular and Optical Physics. 26:L789-L792
A crossed beam technique has been used to investigate the angular distribution of electrons photodetached from the weakly-bound excited (2p3)2D state of the C- ion via the (2p2) 3P epsilon s,d channels. At a photon energy of 2.076 eV the asymmetry pa
Publikováno v:
Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms. 79:162-165
A crossed laser-ion beam apparatus has been used to determine the electron affinity of Li and to measure cross sections for single photon-single electron detachment from Li − . Photoelectron production via the resolved 2 Sϵp and 2 Pϵs channels ha
Autor:
A. Joshua Wand, Martin J. Dellwo
Publikováno v:
Journal of the American Chemical Society. 115:1886-1893
Nuclear magnetic resonance spectral densities corresponding to three-site jump and continuous diffusion models for methyl rotation have been derived for methyl-non-methyl and methyl-methyl dipolar interactions. These spectral densities have been cast
Publikováno v:
Biochemistry. 31:3645-3652
The fast internal dynamics of human ubiquitin have been studied by the analysis of 15N relaxation of backbone amide nitrogens. The amide 15N resonances have been assigned by use of heteronuclear multiple-quantum spectroscopy. Spin lattice relaxation
Publikováno v:
Physical Review A. 45:1544-1547
The method of threshold-photodetachment spectroscopy has been used to measure the electron affinity of Li. Changes in the partial cross sections for the resolved h\ensuremath{\nu}+${\mathrm{Li}}^{\mathrm{\ensuremath{-}}}$(2 $^{1}$S)\ensuremath{\right