Zobrazeno 1 - 5
of 5
pro vyhledávání: '"J. David Innis"'
Autor:
Gregory M. Adamson, Katherine Sarlo, J. David Innis, Victoria L. Hollis, D. Bruce Kirchner, Laura S. Babcock
Publikováno v:
Journal of Immunotoxicology. 1:71-77
Use of enzymes in cosmetic products is novel and the safety of these products is not well understood. The safety of a prototype enzyme-containing body moisturizer lotion was tested via measures of skin compatibility and potential to induce protease-s
Autor:
Keith A. Booman, L.H. Bruner, Richard I. Sedlak, Arthur S. Rothenstein, D.M. Bagley, William C. McCormick, Janis Demetrulias, J. David Innis, David J. Neun, Phillip L. Casterton, John E. Heinze
Publikováno v:
Journal of Toxicology: Cutaneous and Ocular Toxicology. 13:127-155
Nine in vitro candidate tests for estimating eye irritation potential were evaluated as potential replacements for the Draize test. The tests examined were a cell protein assay, the chorioallantoic membrane vascularization assay, a cell protein assay
Publikováno v:
Toxicology and Applied Pharmacology. 90:445-453
The toxic potential of the combination of morphine and Adriamycin (doxorubicin) has been evaluated in mice. Intravenous administration of 20 or 40 mg Adriamycin/kg resulted in a dose-related mortality beginning 4 days postdose. Increasing the dose of
Autor:
J. David Innis, Duane G. Wenzel
Publikováno v:
Pharmacological Research Communications. 15:167-172
The nonsteroidal antiinflammatory drugs: acetylsalicylic acid, salicylic acid, sulfinpyrazone and indomethacin were tested at 10(-10) - 10(-5) M for their effect on arrhythmias of monolayer cultures of neonatal rat heart myocytes. Arrhythmias produce
Autor:
J. David Innis, Aryeh Hurwitz
Publikováno v:
Toxicology and applied pharmacology. 90(3)
The mechanism by which morphine interacts with Adriamycin to increase hematocrit has been investigated in mice. Treatment with Adriamycin (12.8 mg/kg, iv) or morphine (20 mg/kg, sc) resulted in slight increases in hematocrit 30 min postdose, while an