Zobrazeno 1 - 10
of 44
pro vyhledávání: '"J. David Haynes"'
Autor:
Sheetij Dutta, Lisa S. Dlugosz, Damien R. Drew, Xiaopeng Ge, Diouf Ababacar, Yazmin I. Rovira, J. Kathleen Moch, Meng Shi, Carole A. Long, Michael Foley, James G. Beeson, Robin F. Anders, Kazutoyo Miura, J. David Haynes, Adrian H. Batchelor
Publikováno v:
PLoS Pathogens, Vol 10, Iss 1 (2014)
Externí odkaz:
https://doaj.org/article/73b6ec42cfcb4ac0b527e0b95511ad87
Autor:
Sheetij Dutta, Lisa S Dlugosz, Damien R Drew, Xiaopeng Ge, Diouf Ababacar, Yazmin I Rovira, J Kathleen Moch, Meng Shi, Carole A Long, Michael Foley, James G Beeson, Robin F Anders, Kazutoyo Miura, J David Haynes, Adrian H Batchelor
Publikováno v:
PLoS Pathogens, Vol 9, Iss 12, p e1003840 (2013)
Malaria vaccine candidate Apical Membrane Antigen-1 (AMA1) induces protection, but only against parasite strains that are closely related to the vaccine. Overcoming the AMA1 diversity problem will require an understanding of the structural basis of c
Externí odkaz:
https://doaj.org/article/8b57d05c22124733aa9aa5fc66898def
Autor:
B Kim Lee Sim, David L Narum, Rana Chattopadhyay, Adriana Ahumada, J David Haynes, Steven R Fuhrmann, Jennifer N Wingard, Hong Liang, J Kathleen Moch, Stephen L Hoffman
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18393 (2011)
The malaria parasite Plasmodium falciparum EBA-175 binds its receptor sialic acids on glycophorin A when invading erythrocytes. The receptor-binding region (RII) contains two cysteine-rich domains with similar cysteine motifs (F1 and F2). Functional
Externí odkaz:
https://doaj.org/article/35e4e1b5664b4a81873e4517b2968be5
Autor:
Sheetij Dutta, JoAnn S Sullivan, Katharine K Grady, J David Haynes, Jack Komisar, Adrian H Batchelor, Lorraine Soisson, Carter L Diggs, D Gray Heppner, David E Lanar, William E Collins, John W Barnwell
Publikováno v:
PLoS ONE, Vol 4, Iss 12, p e8138 (2009)
A Plasmodium falciparum 3D7 strain Apical Membrane Antigen-1 (AMA1) vaccine, formulated with AS02(A) adjuvant, slowed parasite growth in a recent Phase 1/2a trial, however sterile protection was not observed. We tested this AS02(A), and a Montanide I
Externí odkaz:
https://doaj.org/article/bb5f1754422943d2bdcfca2852651770
Autor:
Michael J. Nold, David L. Narum, Dan E. Sturdevant, Karine Reiter, Scott J. Geromanos, Prakash Srinivasan, J. Kathleen Moch, Julian C. Rayner, Krishan Kumar, Thomas D. Otto, Vijayaraj Nagarajan, J. David Haynes, Raul Herrera, Stephen F. Porcella, R. Burke Squires
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-17 (2017)
Scientific Reports
Scientific Reports
The symptoms of malaria are brought about by blood-stage parasites, which are established when merozoites invade human erythrocytes. Our understanding of the molecular events that underpin erythrocyte invasion remains hampered by the short-period of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf7001d0b0b4159c05222ea431c5a35d
https://eprints.gla.ac.uk/157840/1/157840.pdf
https://eprints.gla.ac.uk/157840/1/157840.pdf
EBA-175, erythrocyte binding antigen 175, is a 175-kDa antigen of Plasmodium falciparum which has been shown to be involved in the recognition of erythrocytes by merozoites and may be involved in the process of erythrocyte invasion. Invasion of eryth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80daf93aa7180dd93e2244b95e5fe167
https://doi.org/10.1016/0166-6851(93)90033-t
https://doi.org/10.1016/0166-6851(93)90033-t
Autor:
J. David Haynes, David L. Narum, Xavier Ambroggio, Prakash Srinivasan, Wandy L. Beatty, Louis H. Miller, John C. Boothroyd, Susan K. Pierce, Jessica S. Tyler, Ababacar Diouf, Raul Herrera, J. Kathleen Moch
Publikováno v:
Proceedings of the National Academy of Sciences. 108:13275-13280
The commitment of Plasmodium merozoites to invade red blood cells (RBCs) is marked by the formation of a junction between the merozoite and the RBC and the coordinated induction of the parasitophorous vacuole. Despite its importance, the molecular ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0326abbeb3b1c7d207560d5e1858b95
https://doi.org/10.1073/pnas.1110303108
https://doi.org/10.1073/pnas.1110303108
Autor:
Adrian H. Batchelor, Robert A. Gasser, Christopher D. Pool, Lisa S. Dlugosz, Joshua W. Clayton, Sheetij Dutta, J. David Haynes
Publikováno v:
Infection and Immunity. 78:661-671
Antibodies against apical membrane antigen 1 (AMA1) inhibit invasion ofPlasmodiummerozoites into red cells, and a large number of single nucleotide polymorphisms on AMA1 allow the parasite to escape inhibitory antibodies. The availability of a crysta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6560a559569d05fb3af5e4f563545219
https://doi.org/10.1128/iai.00866-09
https://doi.org/10.1128/iai.00866-09
Autor:
J. Kathleen Moch, J. David Haynes, Alan W. Thomas, Arnoldo Barbosa, Jeffrey D. Snavely, David E. Lanar, Sheetij Dutta, Lisa A. Ware
Publikováno v:
Infection and Immunity. 73:2116-2122
Antibodies against apical membrane antigen 1 (AMA-1) of Plasmodium falciparum inhibit merozoite invasion into erythrocytes. Invasion-inhibitory polyclonal AMA-1 antibodies inhibit secondary proteolytic processing and surface redistribution of AMA-1 o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8e0f106843c7787e9e7ff5a450f550b
https://doi.org/10.1128/iai.73.4.2116-2122.2005
https://doi.org/10.1128/iai.73.4.2116-2122.2005
Autor:
Sheetij Dutta, Lisa S. Dlugosz, Damien R. Drew, Xiaopeng Ge, Diouf Ababacar, Yazmin I. Rovira, J. Kathleen Moch, Meng Shi, Carole A. Long, Michael Foley, James G. Beeson, Robin F. Anders, Kazutoyo Miura, J. David Haynes, Adrian H. Batchelor
Publikováno v:
PLoS Pathogens, Vol 10, Iss 1 (2014)
PLoS Pathogens
PLoS Pathogens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a32c241b82db5844d21f2f4b595e0e5a
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904780/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904780/?tool=EBI