Zobrazeno 1 - 10
of 56
pro vyhledávání: '"J. David Castle"'
Autor:
Alex J. B. Kreutzberger, Volker Kiessling, Christopher Stroupe, Binyong Liang, Julia Preobraschenski, Marcelo Ganzella, Mark A. B. Kreutzberger, Robert Nakamoto, Reinhard Jahn, J. David Castle, Lukas K. Tamm
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Regulated exocytosis of neuronal synaptic vesicles is substantially faster than that of endocrine dense core vesicles despite similar molecular machineries. Here authors compare SNARE-mediated fusion of purified synaptic vesicles with insulin vesicle
Externí odkaz:
https://doaj.org/article/4a79a606ae254e35b295a19f8e1dafc2
Autor:
Brittany A Martínez, Rosalie G Hoyle, Scott Yeudall, Mitchell E Granade, Thurl E Harris, J David Castle, Norbert Leitinger, Michelle L Bland
Publikováno v:
PLoS Genetics, Vol 16, Iss 11, p e1009192 (2020)
During infection, cellular resources are allocated toward the metabolically-demanding processes of synthesizing and secreting effector proteins that neutralize and kill invading pathogens. In Drosophila, these effectors are antimicrobial peptides (AM
Externí odkaz:
https://doaj.org/article/68fbace5dc1f44709095beda0b986904
Autor:
Alex J B Kreutzberger, Volker Kiessling, Catherine A Doyle, Noah Schenk, Clint M Upchurch, Margaret Elmer-Dixon, Amanda E Ward, Julia Preobraschenski, Syed S Hussein, Weronika Tomaka, Patrick Seelheim, Iman Kattan, Megan Harris, Binyong Liang, Anne K Kenworthy, Bimal N Desai, Norbert Leitinger, Arun Anantharam, J David Castle, Lukas K Tamm
Publikováno v:
eLife, Vol 9 (2020)
Insulin secretion from β-cells is reduced at the onset of type-1 and during type-2 diabetes. Although inflammation and metabolic dysfunction of β-cells elicit secretory defects associated with type-1 or type-2 diabetes, accompanying changes to insu
Externí odkaz:
https://doaj.org/article/6a3003b24de34ef2a6a794b8fb9446e1
Autor:
J David Castle
Publikováno v:
Exocytosis: From Molecules to Cells ISBN: 9780750337717
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95651678e9dc216c1c5ad567d20032f8
https://doi.org/10.1088/978-0-7503-3771-7ch2
https://doi.org/10.1088/978-0-7503-3771-7ch2
Autor:
Syed S Hussein, Anne K. Kenworthy, Megan T. Harris, Alex J. B. Kreutzberger, Margaret Elmer-Dixon, Arun Anantharam, Volker Kiessling, Bimal N. Desai, Julia Preobraschenski, Iman Kattan, Norbert Leitinger, Noah A. Schenk, Amanda E. Ward, Patrick Seelheim, Catherine A. Doyle, Clint M Upchurch, Binyong Liang, J. David Castle, Weronika Tomaka, Lukas K. Tamm
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
Insulin secretion from β-cells is reduced at the onset of type-1 and during type-2 diabetes. Although inflammation and metabolic dysfunction of β-cells elicit secretory defects associated with type-1 or type-2 diabetes, accompanying changes to insu
Autor:
J. David Castle, Syed S Hussein, Clint M Upchurch, Volker Kiessling, Binyong Liang, Patrick Seelheim, Megan T. Harris, Catherine A. Doyle, Julia Preobraschenski, Lukas K. Tamm, Anne K. Kenworthy, Iman Kattan, Weronika Tomaka, Noah A. Schenk, Alex J. B. Kreutzberger, Bimal N. Desai, Margaret Elmer-Dixon, Norbert Leitinger, Amanda E. Ward, Arun Anantharam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9d20a0015966b9d5d1c7b544410c829
https://doi.org/10.7554/elife.62506.sa2
https://doi.org/10.7554/elife.62506.sa2
Autor:
J. David Castle, John J.M. Bergeron
Publikováno v:
Traffic
On April 10, 2020, a treasured cell biologist and ardent champion of the Golgi complex passed away. This has caused deep sadness, and we seek to commemorate her remarkable scientific contributions, her warm and generous personality, and her endearing
Autor:
Syed Saad Hussain, Anna M. Castle, Peter Arvan, Catherine A. Doyle, Megan T. Harris, J. David Castle, Candice M Inouye, Alex J. B. Kreutzberger
Publikováno v:
Molecular Biology of the Cell
In pancreatic β-cells, insulin granule membranes are enriched in cholesterol and are both recycled and newly generated. Cholesterol’s role in supporting granule membrane formation and function is poorly understood. ATP binding cassette transporter
Autor:
Marcelo Ganzella, Alex J. B. Kreutzberger, Reinhard Jahn, Mark A. B. Kreutzberger, Lukas K. Tamm, Binyong Liang, Robert K. Nakamoto, Volker Kiessling, Julia Preobraschenski, Christopher Stroupe, J. David Castle
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Nature Communications
Nature Communications
Regulated exocytosis of synaptic vesicles is substantially faster than of endocrine dense core vesicles despite similar molecular machineries. The reasons for this difference are unknown and could be due to different regulatory proteins, different sp
Autor:
Mitchell E. Granade, Thurl E. Harris, Rosalie G. Hoyle, Brittany A. Martinez, Michelle L. Bland, J. David Castle, Scott Yeudall, Norbert Leitinger
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 16, Iss 11, p e1009192 (2020)
PLoS Genetics, Vol 16, Iss 11, p e1009192 (2020)
During infection, cellular resources are allocated toward the metabolically-demanding processes of synthesizing and secreting effector proteins that neutralize and kill invading pathogens. In Drosophila, these effectors are antimicrobial peptides (AM