Zobrazeno 1 - 10
of 720
pro vyhledávání: '"J. Dannenberg"'
Autor:
Rita Peila, Xiaonan Xue, Qibin Qi, Andrew J. Dannenberg, Matthew A. Allison, Karen C. Johnson, Michael J. LaMonte, Robert A. Wild, Bernhard Haring, Kathy Pan, Hilary A. Tindle, Randi Foraker, Nazmus Saquib, Ana Barac, Thomas E. Rohan
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 12 (2023)
Background A lifestyle comprising a healthy diet, light alcohol consumption, no smoking, and moderate or intense physical activity has been associated with reduced risk of cardiovascular disease (CVD). We examined the association of a healthy lifesty
Externí odkaz:
https://doaj.org/article/bcda12c2aa7f4fc8925399789be4832c
Autor:
Byuri Angela Cho, Neil M. Iyengar, Xi Kathy Zhou, Hillary Mendieta, Lisle Winston, Domenick J. Falcone, Jonathan Landa, Monica Morrow, Andrew J. Dannenberg
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-9 (2022)
Abstract Increased trunk fat is associated with an elevated risk of breast cancer in normal-weight postmenopausal women. The main objective of this study was to determine whether levels of trunk fat are associated with changes in breast gene expressi
Externí odkaz:
https://doaj.org/article/c63d8480c8eb44f9a03c8671284995de
Autor:
Julia A. Brown, Katherine Z. Sanidad, Serena Lucotti, Carolin M. Lieber, Robert M. Cox, Aparna Ananthanarayanan, Srijani Basu, Justin Chen, Mengrou Shan, Mohammed Amir, Fabian Schmidt, Yiska Weisblum, Michele Cioffi, Tingting Li, Florencia Madorsky Rowdo, M. Laura Martin, Chun-Jun Guo, Costas A. Lyssiotis, Brian T. Layden, Andrew J. Dannenberg, Paul D. Bieniasz, Benhur Lee, Naohiro Inohara, Irina Matei, Richard K. Plemper, Melody Y. Zeng
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
The gut microbiome is intricately coupled with immune regulation and metabolism, but its role in Coronavirus Disease 2019 (COVID-19) is not fully understood. Severe and fatal COVID-19 is characterized by poor anti-viral immunity and hypercoagulation,
Externí odkaz:
https://doaj.org/article/af4ba1f980974ee5b64d7229b89889c3
Autor:
Paulina M. Wojnarowicz, Marta Garcia Escolano, Yun-Han Huang, Bina Desai, Yvette Chin, Riddhi Shah, Sijia Xu, Saurabh Yadav, Sergey Yaklichkin, Ouathek Ouerfelli, Rajesh Kumar Soni, John Philip, David C. Montrose, John H. Healey, Vinagolu K. Rajasekhar, William A. Garland, Jeremy Ratiu, Yuan Zhuang, Larry Norton, Neal Rosen, Ronald C. Hendrickson, Xi Kathy Zhou, Antonio Iavarone, Joan Massague, Andrew J. Dannenberg, Anna Lasorella, Robert Benezra
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-17 (2021)
Abstract ID proteins are helix-loop-helix (HLH) transcriptional regulators frequently overexpressed in cancer. ID proteins inhibit basic-HLH transcription factors often blocking differentiation and sustaining proliferation. A small-molecule, AGX51, t
Externí odkaz:
https://doaj.org/article/fcc94ce778e043e9991e8da7d30777e4
Autor:
Neil M. Iyengar, Xi Kathy Zhou, Hillary Mendieta, Omar El-Hely, Dilip D. Giri, Lisle Winston, Domenick J. Falcone, Hanhan Wang, Lingsong Meng, Taehoon Ha, Michael Pollak, Monica Morrow, Andrew J. Dannenberg
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-7 (2021)
Abstract Obesity is associated with an increased risk of breast cancer in post-menopausal women and decreased risk in pre-menopausal women. Conversely, in BRCA1/2 mutation carriers, pre-menopausal obesity is associated with early-onset breast cancer.
Externí odkaz:
https://doaj.org/article/9bc77085a3d541aca6d6d81c076de591
Autor:
Rhonda S. Arthur, Xiaonan Xue, Victor Kamensky, Rowan T. Chlebowski, Michael Simon, Juhua Luo, Aladdin H. Shadyab, Marian L. Neuhouser, Hailey Banack, Gloria Y. F. Ho, Dorothy S. Lane, Kathy Pan, Kerryn W. Reding, Sylvia Wassertheil‐Smoller, Andrew J. Dannenberg, Thomas E. Rohan
Publikováno v:
Cancer Medicine, Vol 9, Iss 4, Pp 1581-1599 (2020)
Abstract Background Most studies demonstrating an association between excess adiposity and postmenopausal breast cancer have used anthropometric measures, particularly body mass index (BMI). However, more direct body fat measures may more accurately
Externí odkaz:
https://doaj.org/article/acfa8109e87b49e290a12b20f1cabf3b
Autor:
I-Chun Chen, Deepika Awasthi, Chia-Lang Hsu, Minkyung Song, Chang-Suk Chae, Andrew J. Dannenberg, Juan R. Cubillos-Ruiz
Publikováno v:
J Immunol
Obesity is associated with increased cancer risk and weak responses to vaccination and sepsis treatment. Although dendritic cells (DCs) are fundamental for the initiation and maintenance of competent immune responses against pathogens and tumors, how
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6767fcbc26efa6a0fa89960d49926ea
https://doi.org/10.4049/jimmunol.2100567
https://doi.org/10.4049/jimmunol.2100567
Autor:
Paulina M. Wojnarowicz, Raquel Lima e Silva, Masayuki Ohnaka, Sang Bae Lee, Yvette Chin, Anita Kulukian, Sung-Hee Chang, Bina Desai, Marta Garcia Escolano, Riddhi Shah, Marta Garcia-Cao, Sijia Xu, Rashmi Kadam, Yehuda Goldgur, Meredith A. Miller, Ouathek Ouerfelli, Guangli Yang, Tsutomu Arakawa, Steven K. Albanese, William A. Garland, Glenn Stoller, Jaideep Chaudhary, Larry Norton, Rajesh Kumar Soni, John Philip, Ronald C. Hendrickson, Antonio Iavarone, Andrew J. Dannenberg, John D. Chodera, Nikola Pavletich, Anna Lasorella, Peter A. Campochiaro, Robert Benezra
Publikováno v:
Cell Reports, Vol 29, Iss 1, Pp 62-75.e7 (2019)
Summary: Id helix-loop-helix (HLH) proteins (Id1–4) bind E protein bHLH transcription factors, preventing them from forming active transcription complexes that drive changes in cell states. Id proteins are primarily expressed during development to
Externí odkaz:
https://doaj.org/article/95d35ea0d3dd4fce8521d6c45f7d1b30
Autor:
Sheri A.C. McDowell, Simon Milette, Samuel Doré, Miranda W. Yu, Mark Sorin, Liam Wilson, Lysanne Desharnais, Alyssa Cristea, Ozgun Varol, Aline Atallah, Anikka Swaby, Valérie Breton, Azadeh Arabzadeh, Sarah Petrecca, Hamza Loucif, Aanya Bhagrath, Meghan De Meo, Katherine D. Lach, Marianne S.M. Issac, Benoit Fiset, Roni F. Rayes, Judith N. Mandl, Jörg H. Fritz, Pierre O. Fiset, Peter R. Holt, Andrew J. Dannenberg, Jonathan D. Spicer, Logan A. Walsh, Daniela F. Quail
Publikováno v:
Journal of Experimental Medicine. 220
Obesity is characterized by chronic systemic inflammation and enhances cancer metastasis and mortality. Obesity promotes breast cancer metastasis to lung in a neutrophil-dependent manner; however, the upstream regulatory mechanisms of this process re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e0513b49a5eb34570c41164f108f0db
https://doi.org/10.1084/jem.20220509
https://doi.org/10.1084/jem.20220509
Autor:
Fahrettin Haczeyni, Sandra Steensels, Benjamin D. Stein, James M. Jordan, Le Li, Vincent Dartigue, Selenay S. Sarklioglu, Jixuan Qiao, Xi K. Zhou, Andrew J. Dannenberg, Neil M. Iyengar, Haiyuan Yu, Lewis C. Cantley, Baran A. Ersoy
Publikováno v:
bioRxiv
Mitochondria-rich brown adipocytes dissipate cellular fuel as heat by thermogenic energy expenditure (TEE). Prolonged nutrient excess or cold exposure impair TEE and contribute to the pathogenesis of obesity, but the mechanisms remain incompletely un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bd5204d46b6e6e663d2305ede515938
https://europepmc.org/articles/PMC10187325/
https://europepmc.org/articles/PMC10187325/
