Výsledky vyhledávání - "J. D. Wirtschafter"

Doxil-induced chemomyectomy: effectiveness for permanent removal of orbicularis oculi muscle in monkey eyelid

Publikováno v: Investigative ophthalmologyvisual science. 42(6)

To test the safety and effectiveness of Doxil chemomyectomy in monkey eyelids using treatment schedules and doses similar to those proposed for the human blepharospasm patients in Phase I and II trials.Bupivacaine/hyaluronidase and Doxil were injecte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dfb34f205d52268bcd4be264b59322c9
https://pubmed.ncbi.nlm.nih.gov/11328736

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Complex three-dimensional patterns of myosin isoform expression: differences between and within specific extraocular muscles

Autor: L K, McLoon, L, Rios, J D, Wirtschafter

Publikováno v: Journal of muscle research and cell motility. 20(8)

Because complex structural differences in adult extraocular muscles may have physiological and pathophysiological significance, the three-dimensional pattern of myosin heavy chain (MHC) isoform expression within the orbital and global layers of the m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5d8f72ebfb4015696b7b7f229e508ac2
https://pubmed.ncbi.nlm.nih.gov/10730580

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Homonucleotide expansion and contraction mutations of PAX2 and inclusion of Chiari 1 malformation as part of renal-coloboma syndrome

Autor: L A, Schimmenti, H H, Shim, J D, Wirtschafter, V A, Panzarino, C E, Kashtan, S J, Kirkpatrick, D S, Wargowski, T D, France, E, Michel, W B, Dobyns

Publikováno v: Human mutation. 14(5)

Renal-Coloboma syndrome, an autosomal dominant disorder characterized by colobomatous eye defects, vesicoureteral reflux, and abnormal kidneys, results from mutations in PAX2. The purpose of this study was to identify mutations in PAX2 and understand

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d8d69ae3de045d847c1a6d4f980e11cc
https://pubmed.ncbi.nlm.nih.gov/10533062

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Direct injection of liposome-encapsulated doxorubicin optimizes chemomyectomy in rabbit eyelid

Autor: L K, McLoon, J D, Wirtschafter

Publikováno v: Investigative ophthalmologyvisual science. 40(11)

Doxorubicin chemomyectomy presently represents the only permanent, nonsurgical treatment for blepharospasm and hemifacial spasm. The major deterrent to an otherwise extremely effective treatment protocol is the development in patients of localized in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8f126f72ce4d8bc4f90f65cf0dd3765a
https://pubmed.ncbi.nlm.nih.gov/10509650

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N-CAM is expressed in mature extraocular muscles in a pattern conserved among three species

Autor: L K, McLoon, J D, Wirtschafter

Publikováno v: Investigative ophthalmologyvisual science. 37(2)

Extraocular muscles express a number of characteristics not normally seen in mature skeletal muscle. The expression of neural cell adhesion molecule, N-CAM, was assessed immunohistochemically in the extraocular muscles of rabbits, monkeys, and humans

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e407a79f424401c7db86fa86d57edbe1
https://pubmed.ncbi.nlm.nih.gov/8603836

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Chemomyectomy of the orbicularis oculi muscles for the treatment of localized hemifacial spasm

Autor: J D, Wirtschafter

Publikováno v: Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society. 14(4)

To report our experience with doxorubicin chemomyectomy as an alternative to other treatments for hemifacial spasm (HFS).A prospective, open study Phase I clinical trial of chemomyectomy.A hospital-based, referral neuro-ophthalmology and oculoplastic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b7b80986f95cc4bd25bdbd9ccd5ada1a
https://pubmed.ncbi.nlm.nih.gov/7881523

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Management of ophthalmic complications in surgery of the brain stem

Autor: M, Rubenfeld, J D, Wirtschafter

Publikováno v: Neurosurgery clinics of North America. 4(3)

This article reviews assessment and rehabilitation of abnormalities of the afferent and efferent visual system that may follow surgery of the brain stem. Attention is drawn to newer techniques of assessment (contrast sensitivities and binocular visua

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8d6d385fe94a53a700cce0d4fc73e6b0
https://pubmed.ncbi.nlm.nih.gov/8353455

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Papilledema and intraspinal lumbar paraganglioma

Autor: D R, Hardten, D Y, Wen, J D, Wirtschafter, J H, Sung, D L, Erickson

Publikováno v: Journal of clinical neuro-ophthalmology. 12(3)

Optic nervehead swelling is most frequently caused by ocular or intracranial lesions. The case presented here demonstrates that the spinal subarachnoid space must also be considered as a potential site for a lesion causing optic nervehead swelling. A

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9906bef33bf5d9bbe4efda0f0f51f1ea
https://pubmed.ncbi.nlm.nih.gov/1401159

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Esthesioneuroblastoma presenting as sudden unilateral blindness. Histopathologic confirmation of optic nerve demyelination

Autor: E L, Berman, A, Chu, J D, Wirtschafter, J D, Cameron, J C, Manivel, A J, Duvall, S J, Haines

Publikováno v: Journal of clinical neuro-ophthalmology. 12(1)

We report here a case of esthesioneuroblastoma an 11-year-old girl presenting as acute loss of vision with minimal evidence of orbital, nasal, or paranasal sinus disease, a rare presenting symptom for this tumor. The initial diagnosis was postviral o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cf1d74560e68b027f8daae15eb8b18d2
https://pubmed.ncbi.nlm.nih.gov/1532598

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