Zobrazeno 1 - 10 of 40 pro vyhledávání: '"J. D. Winkler"'
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Endogenous retinoid X receptors can function as hormone receptors in pituitary cells
Autor: K D Davis, T J Berrodin, J E Stelmach, J D Winkler, M A Lazar
Publikováno v: Molecular and Cellular Biology. 14:7105-7110
Retinoids regulate gene transcription by interacting with both retinoic acid (RA) receptors (RARs) and retinoid X receptors (RXRs). Since unliganded RXRs can act as heterodimerization partners for RARs and other nuclear hormone receptors, it is uncle
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0565bc594fdc82aa1bcdeb85b1a7235a
https://doi.org/10.1128/mcb.14.11.7105
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3
Endogenous Retinoid X Receptors Can Function as Hormone Receptors in Pituitary Cells
Autor: J E Stelmach, Thomas J. Berrodin, Mitchell A. Lazar, J D Winkler, Kelly D. Davis
Publikováno v: Molecular and Cellular Biology. 14:7105-7110
Retinoids regulate gene transcription by interacting with both retinoic acid (RA) receptors (RARs) and retinoid X receptors (RXRs). Since unliganded RXRs can act as heterodimerization partners for RARs and other nuclear hormone receptors, it is uncle
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2f36ba6902060f7aadd30d2d257feb5
https://doi.org/10.1128/mcb.14.11.7105-7110.1994
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4
Influence of isoproterenol and phosphodiesterase inhibitors on platelet-activating factor biosynthesis in the human neutrophil
Autor: A N Fonteh, J D Winkler, T J Torphy, J Heravi, B J Undem, F H Chilton
Publikováno v: The Journal of Immunology. 151:339-350
Increasing cellular levels of cAMP inhibit eicosanoid production in the human neutrophil; however, little is known about the effects of cAMP on platelet-activating factor (PAF) biosynthesis in this cell. In the current study, the beta-adrenergic rece
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::87625adb1ac4a77db77962378a30308d
https://doi.org/10.4049/jimmunol.151.1.339
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6
An indolocarbazole inhibitor of human checkpoint kinase (Chk1) abrogates cell cycle arrest caused by DNA damage
Autor: J R, Jackson, A, Gilmartin, C, Imburgia, J D, Winkler, L A, Marshall, A, Roshak
Publikováno v: Cancer research. 60(3)
Many cancer therapies cause DNA damage to effectively kill proliferating tumor cells; however, a major limitation of current therapies is the emergence of resistant tumors following initial treatment. Cell cycle checkpoints are involved in the respon
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::775995f3082ec0fb22568d5643d7576c
https://pubmed.ncbi.nlm.nih.gov/10676638
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7
Pharmacological effects of SB 220025, a selective inhibitor of P38 mitogen-activated protein kinase, in angiogenesis and chronic inflammatory disease models
Autor: J R, Jackson, B, Bolognese, L, Hillegass, S, Kassis, J, Adams, D E, Griswold, J D, Winkler
Publikováno v: The Journal of pharmacology and experimental therapeutics. 284(2)
Chronic inflammatory diseases often are accompanied by intense angiogenesis, supporting the destructive proliferation of inflammatory tissues. A model of inflammatory angiogenesis is the murine air pouch granuloma, which has a hyperangiogenic compone
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9624349cca0df7ad3b0335d56d3d933d
https://pubmed.ncbi.nlm.nih.gov/9454815
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8
Expression of vascular endothelial growth factor in synovial fibroblasts is induced by hypoxia and interleukin 1beta
Autor: J R, Jackson, J A, Minton, M L, Ho, N, Wei, J D, Winkler
Publikováno v: The Journal of rheumatology. 24(7)
To study the mechanism by which hypoxia and inflammatory cytokines mediate angiogenesis in the rheumatoid pannus through their effects on the fibroblast-like type B synoviocyte, the major cell type of normal synovia.Fibroblasts were prepared from syn
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6cd0a5af49594e5b1a463550a31d755d
https://pubmed.ncbi.nlm.nih.gov/9228120
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9
The codependence of angiogenesis and chronic inflammation
Autor: J R, Jackson, M P, Seed, C H, Kircher, D A, Willoughby, J D, Winkler
Publikováno v: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 11(6)
Angiogenesis is the growth of new blood vessels from existing ones. It is an important aspect of new tissue development, growth, and tissue repair. It is also a component of many diseases including cancer, blindness, and chronic inflammation such as
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d99c91375909b9a560762e8caa931a05
https://pubmed.ncbi.nlm.nih.gov/9194526
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10
Inhibitors of coenzyme A-independent transacylase induce apoptosis in human HL-60 cells
Autor: J D, Winkler, T, Eris, C M, Sung, M, Chabot-Fletcher, R J, Mayer, M E, Surette, F H, Chilton
Publikováno v: The Journal of pharmacology and experimental therapeutics. 279(2)
ET-18-O-CH3 (1-O-octadecyl-2-O-methyl-sn-glycero-3-phosphocholine) is an antiproliferative agent, blocking the growth of cancer cells both in vitro and in vivo. However, there is controversy regarding the mechanism leading to its antiproliferative ef
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::02aeab01cc2760db936ab40a2898bab5
https://pubmed.ncbi.nlm.nih.gov/8930205
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