Zobrazeno 1 - 10
of 20
pro vyhledávání: '"J. D. Valentich"'
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 293:G719-G728
Proinflammatory cytokines and eicosanoids are central players in intestinal inflammation. IL-1, a key cytokine associated with intestinal mucosal inflammation, induces COX-2 expression in human colonic myofibroblasts (CMF) and increased prostaglandin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b9b8407a225b8edf42be5c04cff3992
https://doi.org/10.1152/ajpgi.00117.2007
https://doi.org/10.1152/ajpgi.00117.2007
Autor:
Don W. Powell, John F. Di Mari, Jamal I. Saada, Patrick A. Adegboyega, J. D. Valentich, Randy C. Mifflin
Publikováno v:
American Journal of Physiology-Cell Physiology. 282:C824-C834
Elevated mucosal interleukin-1 (IL-1) levels are frequently seen during acute and chronic intestinal inflammation, and IL-1 neutralization lessens the severity of inflammation. One major effect of IL-1 is the increased release of eicosanoid mediators
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e2456731ccaf1fd06ff4cae4d79be16
https://doi.org/10.1152/ajpcell.00388.2001
https://doi.org/10.1152/ajpcell.00388.2001
Publikováno v:
American Journal of Physiology-Cell Physiology. 271:C1993-C2003
The dogfish shark rectal gland (SRG) is histologically complex, containing connective, nerve, and smooth muscle tissue and at least three types of epithelial cells: secretory tubule, central duct, and endothelial. This cellular heterogeneity preclude
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10a48bd7c3cb453569144e01cf190927
https://doi.org/10.1152/ajpcell.1996.271.6.c1993
https://doi.org/10.1152/ajpcell.1996.271.6.c1993
Autor:
Don W. Powell, J. D. Valentich
Publikováno v:
Current Opinion in Gastroenterology. 10:645-651
A major challenge in gastrointestinal immunophysiology is to define the mucosal cells and soluble mediators whose integrated actions modulate gut absorption, secretion, motility, and blood flow. This knowledge has immense significance not only for at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbf2fb06b92a29c81714e2d43026c1ea
https://doi.org/10.1097/00001574-199411000-00013
https://doi.org/10.1097/00001574-199411000-00013
Autor:
J. D. Valentich, T. W. Ecay
Publikováno v:
American Journal of Physiology-Cell Physiology. 265:C422-C431
Isoprenylated proteins function in the processes of signal transduction and membrane vesicle trafficking. To investigate the role of isoprenylated proteins in secretagogue-stimulated epithelial ion transport, we studied the effects of lovastatin, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afc95bb7f7b128dfbfde388dd601e4e4
https://doi.org/10.1152/ajpcell.1993.265.2.c422
https://doi.org/10.1152/ajpcell.1993.265.2.c422
Publikováno v:
American Journal of Physiology-Cell Physiology. 260:C1125-C1130
Monolayer cultures of shark rectal gland (SRG) epithelial cells were treated with atriopeptin (AP), and the effects on Cl- secretion and intracellular guanosine 3',5'-cyclic monophosphate (cGMP) accumulation were examined. Basolateral or apical expos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdbdc2c34cd9af6407fc2ca22815d352
https://doi.org/10.1152/ajpcell.1991.260.5.c1125
https://doi.org/10.1152/ajpcell.1991.260.5.c1125
Autor:
W. M. Moran, J. D. Valentich
Publikováno v:
American Journal of Physiology-Cell Physiology. 260:C824-C831
Employing microelectrode techniques we have assessed the cellular electrophysiological properties of shark rectal gland (SRG) cells in primary culture. In the absence of secretagogues a 10-fold reduction in the Cl- concentration of the apical superfu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0105e2e510234a1c35970fe66571f5bd
https://doi.org/10.1152/ajpcell.1991.260.4.c824
https://doi.org/10.1152/ajpcell.1991.260.4.c824
Autor:
J. D. Valentich, M. J. Welsh, M. C. Iannuzzi, Shelley A. Grubman, Douglas M. Jefferson, K. W. Klinger, Ming Li, F. C. Marini, Henry L. Dorkin
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 259:L496-L505
Continuous epithelial cell lines from individuals with cystic fibrosis (CF) and normal controls are required to understand the genetic and cellular defects in CF. We used retroviruses to transduce SV40 large T antigen into nasal epithelial cells. Tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8416c10df854fa5ef6f14336ec46305d
https://doi.org/10.1152/ajplung.1990.259.6.l496
https://doi.org/10.1152/ajplung.1990.259.6.l496
Autor:
Randy C. Mifflin, Jamal I. Saada, Sheila E. Crowe, A. B. West, J. D. Valentich, Don W. Powell
Publikováno v:
The American journal of physiology. 277(1)
Myofibroblasts are a unique group of smooth-muscle-like fibroblasts that have a similar appearance and function regardless of their tissue of residence. Through the secretion of inflammatory and anti-inflammatory cytokines, chemokines, growth factors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fc5243daaa6246fa3b3e2732fd2c7df
https://pubmed.ncbi.nlm.nih.gov/10409103
https://pubmed.ncbi.nlm.nih.gov/10409103
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 281(3)
The sensitivity of the Ussing-chambered rat colon to stimulation of Cl- secretion (as measured by the change in short-circuit current) by exogenous platelet-activating factor (PAF) was increased significantly by washing the colon in vitro with Ringer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f181bb06c30094890e33ed2aa7d480b0
https://pubmed.ncbi.nlm.nih.gov/9190862
https://pubmed.ncbi.nlm.nih.gov/9190862