Výsledky vyhledávání - "J. D. MacEwen"

Long-term inhalation toxicity of hydrazine*1

Autor: J. T. Young, R. E. Schmidt, Richard H. Bruner, E.R. Kinkead, R. L. Eason, A. Hall, C. C. Haun, D. E. Prentice, G. B. Hubbard, E. H. Vernot, J D MacEwen

Publikováno v: Fundamental and Applied Toxicology. 5:1050-1064

Year-long intermittent exposures of rats, mice, hamsters, and dogs to hydrazine were conducted using concentrations of 0.05, 0.25, 1.0, and 5.0 ppm. Rats were held 18 months postexposure; hamsters, 1 year postexposure; mice, 15 months postexposure; a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::69121eb8759bed02e46c535781715b7f
https://doi.org/10.1016/0272-0590(85)90141-1

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Long-Term Inhalation Toxicity of Hydrazine

Autor: E. H. VERNOT, J. D. MACEWEN, R. H. BRUNER, C. C. HAUN, E. R. KINKEAD, D. E. PRENTICE, A. HALL, R. E. SCHMIDT, R. L. EASON, G. B. HUBBARD, J. T. YOUNG

Publikováno v: Toxicological Sciences. 5:1050-1064

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::73fad0f790a10f2b499da5fc34af72ca
https://doi.org/10.1093/toxsci/5.6part1.1050

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Methylation of DNA guanine during the course of induction of liver cancer in hamsters by hydrazine or dimethylnitrosamine

Autor: J. D. MacEwen, Ronald C. Shank, Paul M. Newberne, W S Bosan, C L Gaworski

Publikováno v: Carcinogenesis. 8:439-444

Hydrazine is carcinogenic to the mouse and rat, but three earlier studies have reported no carcinogenicity of hydrazine in the hamster. Administration of hydrazine to mice, rats and hamsters results in rapid methylation of liver DNA guanine for which

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99bea1b93a192131db7428f86ad79fc4
https://doi.org/10.1093/carcin/8.3.439

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Acute toxicity and skin corrosion data for some organic and inorganic compounds and aqueous solutions

Autor: E. H. Vernot, J D MacEwen, E.R. Kinkead, C. C. Haun

Publikováno v: Toxicology and Applied Pharmacology. 42:417-423

A table of acute toxicity and skin corrosion data is presented for about 110 organic and inorganic compounds and aqueous solutions. Although the chemicals tested are not new, either as commercial materials or as potential hazards to humans, basic tox

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https://doi.org/10.1016/0041-008x(77)90019-9

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Sampling and Analysis of Phenols in Air

Autor: R. E. Barrow, J. D. Macewen, R. G. Smith

Publikováno v: American Industrial Hygiene Association Journal. 20:142-148

(1959). Sampling and Analysis of Phenols in Air. American Industrial Hygiene Association Journal: Vol. 20, No. 2, pp. 142-148.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a577dae5f4fa71d6d43cf2f0aa52c3c7
https://doi.org/10.1080/00028895909343686

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The Occurrence of Phenols in Air and Combustion Products

Autor: R. E. Barrow, R. G. Smith, J. D. Macewen

Publikováno v: American Industrial Hygiene Association Journal. 20:149-152

(1959). The Occurrence of Phenols in Air and Combustion Products. American Industrial Hygiene Association Journal: Vol. 20, No. 2, pp. 149-152.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b4328e1fe5d71a7dde430c52166a034
https://doi.org/10.1080/00028895909343687

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Comparison of Skin Sensitization Methods: Landsteiner, Maguire and Guinea Pig Maximization

Autor: E. H. Vernot, J. R. Horton, A. Hall, J. D. MacEwen

Comparison was made of three skin sensitization procedures: Landsteiner, Maguire, and Guinea Pig Maximization. Dinitrochlorobenzene, formaldehyde and Carbowax 4000 were selected as strong, weak to moderate, and non-sensitizers, respectively. The Magu

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https://doi.org/10.21236/ada110633

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Toxicity of High Density Jet Fuel Components

Autor: E. H. Vernot, J. D. MacEwen, C. C. Haun

Two constituents of a synthetic jet engine fuel were evaluated for toxicologic effects. These constituents of JP-9 fuel were perhydromethylcyclopentadiene (RJ-4) and bicycloheptadiene (RJ-5). Excess tumor lesions over control levels were seen in a sm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b85f8a5c2b66980d985c1634cd2b88ab
https://doi.org/10.21236/ada068596

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A 90-day vapor inhalation toxicity study of decalin

Autor: C L, Gaworski, C C, Haun, J D, MacEwen, E H, Vernot, R H, Bruner, R L, Amster, M J, Cowan

Publikováno v: Fundamental and applied toxicology : official journal of the Society of Toxicology. 5(4)

A subchronic 90-day inhalation study was conducted to determine the toxic effects of decalin, a commonly used industrial solvent. Experimental groups consisting of male and female beagle dogs, male and female Fischer-344 rats, and female C57BL/6 mice

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7e5863f3eebc00ac9b8d553b9bb2e780
https://pubmed.ncbi.nlm.nih.gov/4043600

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Toxic Hazards Research Unit Annual Technical Report: 1979

Autor: E. H. Vernot, J. D. MacEwen

The research programs of the Toxic Hazards Research Unit (THRU) for the period of June 1978 through May 1979 are reviewed in this report. Chronic toxicity or oncogenic studies were carried out with inhaled methylcyclohexane, tricyclodecane, and purif

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https://doi.org/10.21236/ada075976

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