Zobrazeno 1 - 2
of 2
pro vyhledávání: '"J. D. Lynam"'
Autor:
Lisa C Rohan, Bernard J Moncla, Ratiya Pamela Kunjara Na Ayudhya, Marilyn Cost, Yunda Huang, Fang Gai, Nicole Billitto, J D Lynam, Kara Pryke, Phillip Graebing, Nicole Hopkins, James F Rooney, David Friend, Charlene S Dezzutti
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9310 (2010)
Tenofovir gel has entered into clinical trials for use as a topical microbicide to prevent HIV-1 infection but has no published data regarding pre-clinical testing using in vitro and ex vivo models. To validate our findings with on-going clinical tri
Externí odkaz:
https://doaj.org/article/50f202cf80554ce48f7cec9fec903b9e
Autor:
Marilyn Cost, Lin Wang, David R. Friend, Lisa C. Rohan, J. D. Lynam, Cory Shetler, Kevin Uranker, Charlene S. Dezzutti
Publikováno v:
Journal of Antimicrobial Chemotherapy. 67:2139-2142
Objectives: Coital use of 1% tenofovir gel was shown to be modestly effective at preventing HIV transmission when applied vaginally in the CAPRISA 004 trial. Because the gel is hyperosmolar, which would reduce the integrity of the epithelium and indu