Zobrazeno 1 - 10
of 52
pro vyhledávání: '"J. D. Iglehart"'
Publikováno v:
Oncogene. 18:6000-6012
The hereditary breast cancer susceptibility gene, BRCA2, is considered to be a tumor suppressor gene that may be involved in the cellular response to DNA damage. The transcript for this gene is cell cycle regulated with mRNA levels reaching a peak ju
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66bc22ef6134d6261722dbe82749b13d
https://doi.org/10.1038/sj.onc.1202990
https://doi.org/10.1038/sj.onc.1202990
Autor:
Prema S. Rao, E. Trogan, Alice C. Coogan, Christopher D. Kontos, Kevin G. Peters, Jeffrey R. Marks, Sabita Sankar, Donald A. Berry, J. D. Iglehart
Publikováno v:
British Journal of Cancer
Endothelial receptor tyrosine kinases may play important roles in pathological vascular growth, particularly in tumours. In this study, immunohistochemistry was used to evaluate the expression of a novel endothelial receptor tyrosine kinase, Tie2/Tek
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5dcb6b1279a31f76e07b2a189514c53
https://doi.org/10.1038/bjc.1998.8
https://doi.org/10.1038/bjc.1998.8
Publikováno v:
Radiology. 203:159-163
To evaluate whether an artificial neural network (ANN) can predict breast cancer invasion on the basis of readily available medical findings (ie, mammographic findings classified according to the American College of Radiology Breast Imaging Reporting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad82daf35ba9ff8dc3983c62c5c5ffb7
https://doi.org/10.1148/radiology.203.1.9122385
https://doi.org/10.1148/radiology.203.1.9122385
Autor:
C. Aleman, Jeffrey R. Marks, J. D. Iglehart, Prescott L. Deininger, Donald P. McDonnell, John D. Norris, P. A. Futreal, Roger W. Wiseman, Daju Fan
Publikováno v:
Journal of Biological Chemistry. 270:22777-22782
We have utilized a genetic selection system in yeast to identify novel estrogen-responsive genes within the human genome and to define the sequences in the BRCA-1 gene responsible for its estrogen responsiveness. This approach led to the identificati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::581ba60c6948ca3839c0c4545cbe18b5
https://doi.org/10.1074/jbc.270.39.22777
https://doi.org/10.1074/jbc.270.39.22777
Autor:
Randy L. Jirtle, Tadashi Murase, Mitchell S. Anscher, Barbara Abbott, J. D. Iglehart, Feng Ming Kong
Publikováno v:
Annals of Surgery. 222:155-162
OBJECTIVE: The authors determined whether untreated breast cancer patients have elevated plasma levels of transforming growth factor-beta 1 (TGF-beta 1). SUMMARY BACKGROUND DATA: Increased plasma TGF-beta 1 levels recently were found after chemothera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfad267ac0120120b140d29df8cf528a
https://doi.org/10.1097/00000658-199508000-00007
https://doi.org/10.1097/00000658-199508000-00007
Publikováno v:
Breast Cancer Research and Treatment. 34:253-263
Ductal carcinoma in situ (intraductal carcinoma) of the breast is a commonly recognized and curable clinical entity. Patients with intraductal carcinoma are at risk to develop invasive breast cancer presumably due to a transition from the noninvasive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a998fed17156ebcc73c6d7ebb4c3c35f
https://doi.org/10.1007/bf00689717
https://doi.org/10.1007/bf00689717
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 7(6)
ErbB2 (HER-2) gene amplification and overexpression have been shown to predict a better outcome with doxorubicin-based chemotherapy as opposed to alkylator-based chemotherapy in early stage breast cancer. To understand the mechanism of differential r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::28690a632666c95ee238169091222464
https://pubmed.ncbi.nlm.nih.gov/11410482
https://pubmed.ncbi.nlm.nih.gov/11410482
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 11(2)
Estrogen acts to promote DNA synthesis in the MCF-7 human breast cancer cell line via its interaction with high levels of estrogen receptor. The primary mode of estrogen action has been considered to be through transcriptional activation of genes con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::49df8eeceafcafaabef46e1b88f711d1
https://pubmed.ncbi.nlm.nih.gov/10714766
https://pubmed.ncbi.nlm.nih.gov/10714766
Autor:
S, Clark, J D, Iglehart
Publikováno v:
Advances in surgery. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5ab44d1f2e0c1f55b4d17768188e1835
https://pubmed.ncbi.nlm.nih.gov/10572568
https://pubmed.ncbi.nlm.nih.gov/10572568
Autor:
J. D. Iglehart
During the preceding year, the Duke Breast Cancer Tissue Repository collected breast cancer tissue from 126 patients undergoing surgery for a primary breast cancer. This compares to 124 entries in the first year of the repository. As before, nearly a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27d9a2f72ab250bbc5902a21e082caee
https://doi.org/10.21236/ada391113
https://doi.org/10.21236/ada391113
