Zobrazeno 1 - 10
of 21
pro vyhledávání: '"J. D. Higley"'
Early experience and serotonin transporter gene variation interact to influence primate CNS function
Autor:
A J Bennett, K P Lesch, A Heils, J C Long, J G Lorenz, S E Shoaf, M Champoux, S J Suomi, M V Linnoila, J D Higley
Publikováno v:
Molecular Psychiatry. 7:118-122
Publikováno v:
Psychopharmacology. 146:440-446
Rationale: While the relationship among CSF 5-HIAA, impulsivity, and aggression is well characterized in males, its investigation in females is limited, and no studies have assessed its generalizability across primates by making simultaneous comparis
Autor:
A. J. Bennett, J. D. Higley
Publikováno v:
Alcohol and Alcoholism. 34:402-418
Non-human primates will readily consume an alcohol solution for its reinforcing effects when such a solution is palatable, with some subjects consuming alcohol to excess. In this review, we discuss variables that contribute to high alcohol consumptio
Publikováno v:
Journal of neural transmission. Supplementum. (68)
The radioligand [123I]beta-CIT binds to dopamine transporters in striatum and to serotonin transporters in brainstem. Endogenous dopamine or serotonin may compete with radioligand binding at monoamine transporters. We used alpha-methyl-p-tyrosine (AM
Publikováno v:
Laterality. 9(3)
In this research we examined biological and behavioural correlates of handedness in a subject cohort of 41 free-ranging young female rhesus macaques (Macaca mulatta). Specifically, we examined relationships between handedness and cerebrospinal fluid
Autor:
C S, Barr, T K, Newman, M L, Becker, C C, Parker, M, Champoux, K P, Lesch, D, Goldman, S J, Suomi, J D, Higley
Publikováno v:
Genes, brain, and behavior. 2(6)
Variation in the serotonin transporter gene-linked polymorphic region (5-HTTLPR) has been associated with anxiety and harm avoidance and is weakly associated with a number of neuropsychiatric disorders, including Type II alcoholism, which has a high
Publikováno v:
Journal of medical primatology. 32(2)
We examined relationships among cerebrospinal fluid (CSF) concentrations of the major serotonin metabolite (5-HIAA, 5-hydroxyindoleacetic acid) and significant medical and behavioral outcomes for female rhesus macaques. Based on earlier findings with
Publikováno v:
Developmental neuropsychology. 20(3)
The emergence of hemispheric specialization has important implications for the development of higher order cognitive processes, including language and spatial skills. In this research we sought to further understand psychobiological processes associa
Publikováno v:
Developmental psychobiology. 38(2)
In this research we examined stress-related correlates of hand preference in monkeys. Specifically, we tested the hypothesis that stress reactivity and plasma levels of the stress hormone cortisol are developmentally related to handedness in rhesus m
Publikováno v:
Alcoholism, clinical and experimental research. 24(5)
The purpose of this study was to assess the impact of early rearing and stress-induced rise of plasma cortisol collected during infancy as a biological predictors of adult alcohol consumption in nonhuman primates.Ninety-seven female and male rhesus m