Zobrazeno 1 - 10
of 74
pro vyhledávání: '"J. D. Crapo"'
Autor:
R. P. Bowler, J. Hokanson, M. Taylor, S. Levy, E. M. Canaham, E. Regan, C. Wheeler, M. Nicks, E. Chan, J. D. Crapo
Publikováno v:
European Respiratory Review, Vol 15, Iss 101, Pp 200-201 (2006)
Tobacco smoke contains a high concentration of oxidants and is the primary cause of chronic obstructive pulmonary disease (COPD). Extracellular superoxide dismutase (EC-SOD) is the major antioxidant enzyme in the extracellular space of the lung and i
Externí odkaz:
https://doaj.org/article/6c8957f37eea4da18c1a1ad85c54cb6c
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 15:540-550
Induction of intercellular adhesion molecule-1 (ICAM-1) by proinflammatory cytokines during inflammation plays an important role in regulating polymorphonuclear neutrophil (PMN) migration and localization. In this report, we examined the effects of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69c7ffd5d80c48f75ae2a8caf124b04e
https://doi.org/10.1165/ajrcmb.15.4.8879188
https://doi.org/10.1165/ajrcmb.15.4.8879188
Autor:
J. D. Crapo, Yuh-Chin T. Huang, Karen E. Welty-Wolf, P. J. Fracica, Stephen L. Young, Francis G. Duhaylongsod, Claude A. Piantadosi
Publikováno v:
Journal of Applied Physiology. 78:1823-1831
Diffuse lung injury from hyperoxia is accompanied by low compliance and hypoxemia with disruption of endothelial and alveolar epithelial cell layers. Because both function and content of surfactant in diffuse lung injury decrease in animals and in hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe2664a7aa354c9f4142613b62a9d7c9
https://doi.org/10.1152/jappl.1995.78.5.1823
https://doi.org/10.1152/jappl.1995.78.5.1823
Autor:
Barbara B. Warner, Jean C. Clark, Stephan W. Glasser, Jonathan R. Wispé, Ling-Yi Chang, Chitta R. Dey, J. D. Crapo, J. Neuman, Jeffrey A. Whitsett
Publikováno v:
Journal of Biological Chemistry. 267:23937-23941
To test directly whether mitochondrial Mn-superoxide dismutase (Mn-SOD) protects the lung epithelium from oxygen-induced injury, transgenic mice were produced in which the expression of human Mn-SOD mRNA was directly by transcriptional elements from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44daddb97bbf6d866b9553523ff8977d
https://doi.org/10.1016/s0021-9258(18)35927-1
https://doi.org/10.1016/s0021-9258(18)35927-1
Autor:
Robert R. Mercer, J. D. Crapo
Publikováno v:
Journal of Applied Physiology. 72:1473-1479
Ultrastructural changes in lung parenchymal elastic fibers were studied morphometrically 1, 4, and 12 wk after a single 12-unit dose of pancreatic elastase and in a saline-instilled control group. The mean linear intercept of the parenchymal air spac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ec191bae2d47cd599ecc9f366e4ca98
https://doi.org/10.1152/jappl.1992.72.4.1473
https://doi.org/10.1152/jappl.1992.72.4.1473
Publikováno v:
Transplantation. 52:443-449
Single-lung transplantation in the rat provides a model that allows investigators to study immunologic, cellular, and morphologic changes associated with allograft rejection. We performed morphometric analysis of transplanted and nontransplanted lung
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92f206a84ddac68ba6d1786f34d619e4
https://doi.org/10.1097/00007890-199109000-00009
https://doi.org/10.1097/00007890-199109000-00009
Publikováno v:
Journal of Applied Physiology. 70:2193-2205
This study addressed the question of whether variations in the volume of alveoli and alveolar ducts forming single units of ventilation can significantly influence the distribution and uptake of inspired reactive gases. Quantitative serial section an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3c2d5f805b441e33955747b83e22cb1
https://doi.org/10.1152/jappl.1991.70.5.2193
https://doi.org/10.1152/jappl.1991.70.5.2193
Autor:
Robert R. Mercer, J. D. Crapo
Publikováno v:
Journal of Applied Physiology. 69:756-765
Surface tension forces acting on the thin-wall alveolar septa and the collagen-elastin fiber network are major factors in lung parenchymal micromechanics. Quantitative serial section analysis and morphometric evaluations of planar sections were used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::961617ec35c89b4aeeaf396884de5942
https://doi.org/10.1152/jappl.1990.69.2.756
https://doi.org/10.1152/jappl.1990.69.2.756
Publikováno v:
Behavior genetics. 30(2)
Extracellular superoxide dismutase (EC-SOD) controls the availability of extracellular superoxide and appears to play a role in controlling intercellular signaling. In this role EC-SOD can have potent effects on neurobehavioral function. In previous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5e3520abcdc3fcd7a557d0d4cd741024
https://pubmed.ncbi.nlm.nih.gov/10979599
https://pubmed.ncbi.nlm.nih.gov/10979599
Publikováno v:
Behavior genetics. 28(5)
Extracellular superoxide dismutase (EC-SOD) controls the availability of extracellular superoxide (O2.-), which is important for a variety of physiological pathways, including the primary means of inactivating nitric oxide (NO). The role of EC-SOD in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::50a50b0ada5012f7d0ebafaab15ab14e
https://pubmed.ncbi.nlm.nih.gov/9926619
https://pubmed.ncbi.nlm.nih.gov/9926619