Zobrazeno 1 - 10
of 10
pro vyhledávání: '"J. D. Blackie"'
Publikováno v:
Biotechnology and Bioengineering. 48:201-206
On-line, “real-time” monitoring of product concentration is important for mammalian cell culture fermentation. The continuous measurement of monoclonal antibodies allows for instantaneous determination of cell productivity and effective manipulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2401f4cc1c998704fbb411df376ca868
https://doi.org/10.1002/bit.260480306
https://doi.org/10.1002/bit.260480306
Publikováno v:
Biotechnology and Bioengineering. 45:495-502
On-line optical cell density probes were implemented to continuously monitor the cell densities in mammalian cell bioreactor and to achieve advanced bioreactor controls. We tested cell density probes from six manufacturers in high cell density biorea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc808dc717b34de91910e4db98de9b7e
https://doi.org/10.1002/bit.260450606
https://doi.org/10.1002/bit.260450606
Autor:
A J Lees, J D Blackie
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. 53:640-643
Botulinum toxin A was administered to 19 patients in a double-blind placebo controlled trial. Toxin was more effective than placebo for improving both head position and pain which was measured by an objective rating scale and videofilm assessments. F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ead287a4eae16b633e52aa9ba7126166
https://doi.org/10.1136/jnnp.53.8.640
https://doi.org/10.1136/jnnp.53.8.640
Publikováno v:
Biotechnology and bioengineering. 53(4)
On-line monitoring and control of cell culture fermentation is important for optimal and consistent production of biologicals. In this work, glucose and lactate concentrations are monitored on-line using a commercially available analyzer (Model 2700,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fe1350f3ee5f62ba8bf6a5221448167f
https://pubmed.ncbi.nlm.nih.gov/18634025
https://pubmed.ncbi.nlm.nih.gov/18634025
On-Line Monitoring for Consistent and Optimal Production of Biologicals from Mammalian Cell Cultures
Autor:
Konstantin Konstantinov, Yeong-shou Tsai, R. Taticek, S. S. Ozturk, J. D. Blackie, David Naveh, John Thrift, P. Wu, Cary Matanguihan, S. Yoon
Publikováno v:
Animal Cell Technology ISBN: 9789401062732
Despite all efforts, process monitoring and control of mammalian cell cultures are still limited to physical variables such as pH, DO, and temperature. Although these are important parameters, cellular activities are equally governed by the biochemic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7341548ecb224cb97061ef4bc43d9d3b
https://doi.org/10.1007/978-94-011-5404-8_33
https://doi.org/10.1007/978-94-011-5404-8_33
Autor:
B. Lowe, D. Ladehoff-Guiles, S. S. Ozturk, S. Shackleford, R. Taticek, David Naveh, J. D. Blackie, John Thrift, P. Jorjani
Publikováno v:
Animal Cell Technology ISBN: 9789401062732
Glucose is a major energy source for mammalian cells grown in culture. Although conditions are aerobic, in most cases, glucose is not completely oxidized. Depending on the culture conditions and the cell type, about 50-100% of glucose is converted to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0cf41b4bf6a86dd365520d0577fb97f4
https://doi.org/10.1007/978-94-011-5404-8_56
https://doi.org/10.1007/978-94-011-5404-8_56
Publikováno v:
Animal Cell Technology: Developments Towards the 21st Century ISBN: 9789401041959
A perfusion bioreactor system has been developed for independent control of cell density and metabolite concentrations. The cell density was monitored and controlled using an online optical sensor. A constant environment to the cell was provided by c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8eae80d5e6984bd3bab68280b7d87109
https://doi.org/10.1007/978-94-011-0437-1_47
https://doi.org/10.1007/978-94-011-0437-1_47
Publikováno v:
Clinical and experimental neurology. 30
An acute myopathy complicating life-threatening asthma has been reported with increasing frequency. We present a further 3 patients with this complication. Each patient had nerve conduction studies, electromyography and muscle biopsy performed. The r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3377a881cfb87475cd429264d0e32be2
https://pubmed.ncbi.nlm.nih.gov/7712631
https://pubmed.ncbi.nlm.nih.gov/7712631
Publikováno v:
Acta neurologica Scandinavica. 80(6)
Twenty-nine patients with late-onset epilepsy were followed prospec-tively for a mean period of 4.9 years; 14 had CT evidence of occult cerebral infarction and 15 had normal scans. The prognosis was similar in the 2 groups; 57% and 53% respectively b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a607e161b2a6c3997309dfb624ea51f9
https://pubmed.ncbi.nlm.nih.gov/2618579
https://pubmed.ncbi.nlm.nih.gov/2618579
Publikováno v:
Clinical and experimental neurology. 21
Two patients with cryptococcal meningitis associated with ophthalmological complications are described. One patient developed a cryptococcal fundal lesion which disappeared during chemotherapy. Chronically raised intracranial pressure was associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8ab92ca2867f4c7be52c6ce61e2eb598
https://pubmed.ncbi.nlm.nih.gov/3843225
https://pubmed.ncbi.nlm.nih.gov/3843225