Zobrazeno 1 - 8
of 8
pro vyhledávání: '"J. D. Bergstrom"'
Autor:
Jesus E Madrid, Nicole M Pranic, Samantha Chu, Johanna J D Bergstrom, Rhea Singh, Joclin Rabinovich, Kaycee Arias Lopez, Alexander G Ophir, Katherine A Tschida
Publikováno v:
PLoS ONE, Vol 19, Iss 11, p e0313172 (2024)
Social isolation affects the brain and behavior in a variety of animals, including humans. Studies in traditional laboratory rodents, including mice and rats, have supported the idea that short-term social isolation promotes affiliative social behavi
Externí odkaz:
https://doaj.org/article/9a3482e658174fcc84f1a01a1082d36d
Publikováno v:
Biochemical Journal. 275:61-65
We previously reported the isolation of a partial-length human fetal-liver cDNA encoding farnesyl diphosphate (FPP) synthase (EC 2.5.1.10) and the expression of an active FPP synthase fusion protein in Escherichia coli. The expressed human FPP syntha
Autor:
R B, Lingham, K C, Silverman, H, Jayasuriya, B M, Kim, S E, Amo, F R, Wilson, D J, Rew, M D, Schaber, J D, Bergstrom, K S, Koblan, S L, Graham, N E, Kohl, J B, Gibbs, S B, Singh
Publikováno v:
Journal of medicinal chemistry. 41(23)
We have identified a novel fungal metabolite that is an inhibitor of human farnesyl-protein transferase (FPTase) by randomly screening natural product extracts using a high-throughput biochemical assay. Clavaric acid [24, 25-dihydroxy-2-(3-hydroxy-3-
Autor:
John G. MacConnell, Raymond F. White, Tom S. Chen, J. D. Bergstrom, L. Huang, Richard L. Monaghan, Georgette Dezeny, Brian R. Petuch, Lawrence F. Colwell, Byron H. Arison
Publikováno v:
The Journal of antibiotics. 47(11)
Zaragozic acid A analogues are produced by an unidentified sterile fungus when it is exogenously supplied with 2-thiophenecarboxylic acid, 3-thiophenecarboxylic acid, 2-furoic acid, 2-fluorobenzoic acid, 3-fluorobenzoic acid, or 4-fluorobenzoic acid.
Autor:
M D, Schaber, M B, O'Hara, V M, Garsky, S C, Mosser, J D, Bergstrom, S L, Moores, M S, Marshall, P A, Friedman, R A, Dixon, J B, Gibbs
Publikováno v:
The Journal of biological chemistry. 265(25)
Farnesylation of Ras occurs in vivo on a Cys residue in the C-terminal sequence -Cys-Val-Leu-Ser (termed a CAAX box). This modification is required for Ras membrane localization and cell transforming activity. Using [3H]farnesyl-PPi as precursor and
Publikováno v:
Journal of Biological Chemistry. 259:14548-14553
[3-14C]Acetoacetate, injected subcutaneously into rats, was rapidly incorporated into hepatic cholesterol and fatty acids. Injection of radiolabeled acetoacetate, acetate, or glucose resulted in the preferential incorporation of acetoacetate into cho
Autor:
J D, Bergstrom, J, Edmond
Publikováno v:
Methods in enzymology. 110
Publikováno v:
Federation proceedings. 44(7)
In the course of mammalian development milk has evolved with unique characteristics as has the capacity of the neonatal rat to process this nutrient source. The primary carbon source in milk is fat, which provides two readily utilized metabolites, ac