Zobrazeno 1 - 10
of 132
pro vyhledávání: '"J. Croom"'
Autor:
Jeremiah L. Oyer, Tayler J. Croom-Perez, Md Faqrul Hasan, Javier A. Rivera-Huertas, Sarah B. Gitto, Joanna M. Mucha, Xiang Zhu, Deborah A. Altomare, Robert Y. Igarashi, Alicja J. Copik
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
NK cell therapeutics have gained significant attention as a potential cancer treatment. Towards therapeutic use, NK cells need to be activated and expanded to attain high potency and large quantities for an effective dosage. This is typically done by
Externí odkaz:
https://doaj.org/article/a1322c48c6044a24a3fa333918436d9b
Autor:
Dean A Lee, Jeremiah L Oyer, Md Faqrul Hasan, Tayler J Croom-Perez, Liza D Robles-Carrillo, Sanjana Kumar, Brendan W Andersen, Brian P Tullius, Alicja J Copik, Amanda R Campbell, Thomas A Dieffenthaller, Catherine A Cash, Jonathan E Eloriaga, Meisam Naeimi Kararoudi
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 12 (2023)
Background Inhibitory receptor T-cell Immunoreceptor with Ig and ITIM domains (TIGIT) expressed by Natural Killer (NK) and T cells regulates cancer immunity and has been touted as the next frontier in the development of cancer immunotherapeutics. Alt
Externí odkaz:
https://doaj.org/article/4c6550d3cfe540f09ffbff19f9a789fa
Autor:
Jeremiah L Oyer, Tayler J Croom-Perez, Liza D Robles-Carrillo, Faqrul Hasan, Sanjana Kumar, Brendan W Andersen, Javier A Rivera-Huertas, Brian P Tullius, Alicja J Copik
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/e63b7da5f22e44cc8ce962614d25561c
Autor:
Jeremiah L. Oyer, Tayler J. Croom-Perez, Thomas A. Dieffenthaller, Liza D. Robles-Carillo, Sarah B. Gitto, Deborah A. Altomare, Alicja J. Copik
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
There is a great interest in developing natural killer (NK) cells as adoptive cancer immunotherapy. For off-the-shelf approaches and to conduct multicenter clinical trials, cryopreserved NK cells are the preferred product. However, recent studies rep
Externí odkaz:
https://doaj.org/article/29e98c27f36e4709aaf856cfeec9eaf2
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Cancer immunotherapy is a highly successful and rapidly evolving treatment modality that works by augmenting the body’s own immune system. While various immune stimulation strategies such as PD-1/PD-L1 or CTLA-4 checkpoint blockade result in robust
Externí odkaz:
https://doaj.org/article/0c7a2beb4393491b8fa66ac25df1f0d2
Autor:
Md Faqrul Hasan, Tayler J. Croom-Perez, Jeremiah L. Oyer, Thomas A. Dieffenthaller, Liza D. Robles-Carrillo, Jonathan E. Eloriaga, Sanjana Kumar, Brendan W. Andersen, Alicja J. Copik
Publikováno v:
Cancers; Volume 15; Issue 10; Pages: 2712
Treatments targeting TIGIT have gained a lot of attention due to strong preclinical and early clinical results, particularly with anti-PD-(L)1 therapeutics. However, this combination has failed to meet progression-free survival endpoints in phase III
Autor:
Sandra S. Wise, Haiyan Lu, Rachel M. Speer, John Pierce Wise, Jamie Young, Jennifer H. Toyoda, Idoia Meaza, Tayler J. Croom-Perez, J. Calvin Kouokam, Aaron Specht, Ke Jian Liu, Gary W. Hoyle
Publikováno v:
Toxicology and applied pharmacology. 457
Hexavalent chromium [Cr(VI)] is a well-known and widespread environmental contaminant associated with a variety of adverse health effects, in particular lung cancer. The primary route of exposure in humans is through inhalation. Particulate forms of
Publikováno v:
Toxicol Sci
Lung cancer is the leading cause of cancer death; however, the mechanisms of lung carcinogens are poorly understood. Metals, including hexavalent chromium [Cr(VI)], induce chromosome instability, an early event in lung cancer. Failure of homologous r
Autor:
Faqrul Hasan, Tayler J. Croom-Perez, Thomas Dieffenthaller, Jonathan Eloriaga, Liza Robles-Carrillo, Alicja J. Copik
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundNatural Killer (NK) cells are an important immune cell population crucial for the success of many immunotherapies due to their critical role in both the innate response and in priming an adaptive immune response. Recently, much focus has be