Zobrazeno 1 - 10
of 33
pro vyhledávání: '"J. Crispin Smith"'
Autor:
J. Crispin Smith, David Thomas
Publikováno v:
Toxicology and Applied Pharmacology. 48:43-47
Seven-day-old rats received subcutaneous doses of [ 203 Hg]mercuric chloride and whole body retention of 203 Hg was monitored for the following 21 days. There was a slow decline in body burden of mercury over the first 8 or 9 days after dosing follow
Autor:
Zahir A. Shaikh, J. Crispin Smith
Publikováno v:
Chemico-Biological Interactions. 19:161-171
The mechanisms by which cadmium (Cd) stimulates the synthesis of hepatic and renal metallothionein were investigated in rats. In the liver the incorporation of 35S and 14C labels from cystine showed a lag period of about 2 h and maximum incorporation
Autor:
J. Crispin Smith, Richard D. Irons
Publikováno v:
Chemico-Biological Interactions. 15:289-294
Following chronic CdCl2 administration to rats, more than 98% of the metal in liver supernatant is bound to the low molecular weight binding protein, metallothionein. Simultaneous administration of high doses of Cd and copper salts result in an incre
Autor:
J. Crispin Smith, Chris J. Cappon
Publikováno v:
Journal of Analytical Toxicology. 2:114-120
A simple and practical method has been developed for determining specific forms of selenium In biological materials. The procedure Is based on the selective chelation of tetravalont selenium with 4-nltro-o-phenylenedlamino to form 5-nitroplazselenol,
Publikováno v:
Clinical Chemistry. 20:222-229
A new procedure for alkaline digestion of hair was used for the selective determination of total and inorganic mercury by flameless atomic absorption and the determination of methylmercury by an improved gas-chromatographic procedure. The precision o
Autor:
J. Crispin Smith, Ijaz S. Jamall
Publikováno v:
Archives of Toxicology. 58:102-105
Rats fed a basal, low-selenium diet, or this diet supplemented with 0.1 ppm and 1.0 ppm selenium and treated with cadmium, showed significant reductions in the activity of the selenoenzyme glutathione peroxidase in kidney and liver. Cadmium treatment
Publikováno v:
Canadian Journal of Biochemistry and Physiology. 41:1713-1720
The intracellular distribution of acetylcholinesterase and butyrylcholinesterase in biopsied human rectus abdominis and quadriceps femoris muscles was investigated. Differential ultracentrifugal fractionation showed that the highest specific activity
Publikováno v:
Journal of Neurochemistry. 20:1275-1278
Of The amino acids and derivatives, N-acetyl-L-aspartic acid is present in a uniquely high level (5–6 μmol/g) in the brain of mammals after myelination has occurred. Much lower levels (0·06–0·17 μmol/g) are found prior to this stage of brain
Publikováno v:
Anesthesiology. 24:208-216
Autor:
Chris J. Cappon, J. Crispin Smith
Publikováno v:
Analytical Chemistry. 52:1527-1529