Zobrazeno 1 - 10
of 44
pro vyhledávání: '"J. Craig Ruble"'
Autor:
Jae-Hoon Lee, Jeih-San Liow, Soumen Paul, Cheryl L. Morse, Mohammad B. Haskali, Lester Manly, Sergey Shcherbinin, J. Craig Ruble, Nancy Kant, Emily C. Collins, Hugh N. Nuthall, Paolo Zanotti-Fregonara, Sami S. Zoghbi, Victor W. Pike, Robert B. Innis
Publikováno v:
EJNMMI Research, Vol 10, Iss 1, Pp 1-12 (2020)
Abstract Background Previous studies found that [18F]LSN3316612 was a promising positron emission tomography (PET) radioligand for imaging O-GlcNAcase in nonhuman primates and human volunteers. This study sought to further evaluate the suitability of
Externí odkaz:
https://doaj.org/article/bb5eb72643d84f0aadd17788a06265b4
Autor:
David M. Soro, Jose B. Roque, Jonas W. Rackl, Bohyun Park, Stefan Payer, Yuan Shi, J. Craig Ruble, Alexey L. Kaledin, Mu-Hyun Baik, Djamaladdin G. Musaev, Richmond Sarpong
Publikováno v:
Journal of the American Chemical Society, vol 145, iss 20
Journal of the American Chemical Society, 145 (20)
Journal of the American Chemical Society, 145 (20)
Described herein are studies toward the core modificationof cyclicaliphatic amines using either a riboflavin/photo-irradiation approachor Cu-(I) and Ag-(I) to mediate the process. Structural remodeling ofcyclic amines is explored through oxidative C-
Autor:
Antonio Navarro, Brian A. Schaefer, J. Craig Ruble, Juan A. Rincón, María Luz de la Puente, María Jesús Trigo, María José Nieves-Remacha, José Eugenio de Diego
Publikováno v:
Organic Process Research & Development. 26:891-898
Autor:
Alison Campbell Brewer, H. George Vandeveer, Scott Alan Frank, J. Craig Ruble, C. Richard Nevill
Publikováno v:
Organic Process Research & Development. 25:576-582
Direct asymmetric reductive amination represents an efficient means of converting ketones to α-chiral primary amines, but reported examples are very limited. We describe the development of two sets...
Publikováno v:
Synlett. 31:1608-1612
A convenient procedure for conducting small-scale carbonylations of aryl or benzyl halides in a microwave reactor by using quinolin-8-yl formate is described. The resulting 8-acyloxyquinolines were shown to be more reactive than phenyl esters in acyl
Publikováno v:
Organic Syntheses
Autor:
Leyah A. Schwartz, Kuo-Wei Huang, Michael Holmes, Gilmar A. Brito, Michael J. Krische, Jeffery Richardson, J. Craig Ruble, Théo P. Gonçalves
Publikováno v:
Journal of the American Chemical Society. 141:2087-2096
Iridium complexes modified by PhanePhos catalyze the 2-propanol-mediated reductive coupling of diverse 1,1-disubstituted allenes 1a-1u with fluoral hydrate 2a to form CF(3)-substituted secondary alcohols 3a-3u that incorporate acyclic quaternary carb
Autor:
Peter J. Lindsay-Scott, Victor W. Pike, J. Craig Ruble, Maria Cuadrado, Mohammad B. Haskali, Michael P. Johnson, Susan DuBois, Nancy Kant, Hugh Nuthall, Shuiyu Lu, Jeremy Gilmore, Kevin Michael Ruley, Aneta Kowalski, Enrique Jambrina, S Michelle Morin, Adrian J. Mogg, Soumen Paul, Andrew J. Mannes, Jeih-San Liow, Vanessa N. Barth, Cheryl L. Morse, Sami S. Zoghbi, Nicolas Dreyfus, Robert L. Gladding, Cynthia Darshini Jesudason, Robert B. Innis, Sergey Shcherbinin
Publikováno v:
Science Translational Medicine. 12
We aimed to develop effective radioligands for quantifying brain O-linked-β-N-acetyl-glucosamine (O-GlcNAc) hydrolase (OGA) using positron emission tomography in living subjects as tools for evaluating drug target engagement. Posttranslational modif
Autor:
Emily C. Collins, Cheryl L. Morse, Sergey Shcherbinin, Jeih-San Liow, Lester S Manly, Hugh Nuthall, Jae Hoon Lee, Soumen Paul, Paolo Zanotti-Fregonara, J. Craig Ruble, Robert B. Innis, Mohammad B. Haskali, Nancy Kant, Victor W. Pike, Sami S. Zoghbi
Publikováno v:
EJNMMI Research, Vol 10, Iss 1, Pp 1-12 (2020)
EJNMMI Research
EJNMMI Research
Background Previous studies found that [18F]LSN3316612 was a promising positron emission tomography (PET) radioligand for imaging O-GlcNAcase in nonhuman primates and human volunteers. This study sought to further evaluate the suitability of [18F]LSN
Autor:
Lee, Jae-Hoon, Jeih-San Liow, Paul, Soumen, Morse, Cheryl L., Haskali, Mohammad B., Manly, Lester, Shcherbinin, Sergey, J. Craig Ruble, Kant, Nancy, Collins, Emily C., Nuthall, Hugh N., Zanotti-Fregonara, Paolo, Zoghbi, Sami S., Pike, Victor W., Innis, Robert B.
Additional file 2: Table S2. Demographic and imaging variables for the 10 healthy volunteers in the test-retest study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41932b9ad5d0db8e58dd0ca0c9c97f98