Zobrazeno 1 - 10
of 1 397
pro vyhledávání: '"J. Cowen"'
Autor:
Michael J. Colwell, Hosana Tagomori, Fei Shang, Hoi Iao Cheng, Chloe E. Wigg, Michael Browning, Philip J. Cowen, Susannah E. Murphy, Catherine J. Harmer
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract The role of serotonin in human behaviour is informed by approaches which allow in vivo modification of synaptic serotonin. However, characterising the effects of increased serotonin signalling in human models of behaviour is challenging give
Externí odkaz:
https://doaj.org/article/bcd9b7cb6d184b3988e85f3c3ddb1579
Autor:
A. T. Fischer, T. Tsuji, K. Petronotis, C. G. Wheat, K. Becker, J. F. Clark, J. Cowen, K. Edwards, H. Jannasch, the IODP Expedition, Atlantis Expedition AT18-07 Shipboard Paries
Publikováno v:
Scientific Drilling, Vol 13, Pp 4-11 (2012)
Integrated Ocean Drilling Program (IODP) Expedition 327 (summer 2010) was designed to resolve the nature of fluid-rock interactions in young, upper volcanic crust on the eastern flank of the Juan de Fuca Ridge. Expedition 327 drilled, cased and cored
Externí odkaz:
https://doaj.org/article/9ec418c84bff4f82b40dcea4f496ad1c
Autor:
Fitri Fareez Ramli, Nisha Singh, Uzay E. Emir, Luca M. Villa, Shona Waters, Catherine J. Harmer, Philip J. Cowen, Beata R. Godlewska
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Lithium is an effective augmenting agent for depressed patients with inadequate response to standard antidepressant therapy, but numerous adverse effects limit its use. We previously reported that a lithium-mimetic agent, ebselen, promoted a
Externí odkaz:
https://doaj.org/article/9ac15562ad8942dda42f51e7313e6289
Autor:
Andrea Cipriani, Edoardo Giuseppe Ostinelli, Seena Fazel, Catherine J Harmer, Franco De Crescenzo, Philip J Cowen, Riccardo De Giorgi
Publikováno v:
BMJ Mental Health, Vol 27, Iss 1 (2024)
Background New National Institute for Health and Care Excellence (NICE) guidance endorses the prescription of statins in larger population groups for the prevention of cardiovascular and cerebrovascular morbidity and mortality, especially in people w
Externí odkaz:
https://doaj.org/article/fd148273a60640d9bef028df2e2fd8ac
Autor:
Alexandra C. Pike, Ann L. Sharpley, Rebecca J. Park, Philip J. Cowen, Michael Browning, Erdem Pulcu
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Eating disorders are characterised by altered eating patterns alongside overvaluation of body weight or shape, and have relatively low rates of successful treatment and recovery. Notably, cognitive inflexibility has been implicated in both t
Externí odkaz:
https://doaj.org/article/2d8491c0934244d3b1d253bdd2490fc6
Autor:
Riccardo De Giorgi, Franco De Crescenzo, Philip J. Cowen, Catherine J. Harmer, Andrea Cipriani
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-11 (2023)
Abstract Background Antidepressants are licensed for use in depressive disorders, but non-response and poor adherence to treatment affect a considerable number of patients. Pre-clinical and clinical evidence suggest that statins can augment the effec
Externí odkaz:
https://doaj.org/article/cc60bcfd950d4124aebf26c8aed665c4
Autor:
Riccardo De Giorgi, Nicola Rizzo Pesci, Gianluca Rosso, Giuseppe Maina, Philip J. Cowen, Catherine J. Harmer
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Statins are commonly prescribed medications widely investigated for their potential actions on the brain and mental health. Pre-clinical and clinical evidence suggests that statins may play a role in the treatment of depressive disorders, bu
Externí odkaz:
https://doaj.org/article/7a53a7a9161c45ccaf1d893c32fab30c
Autor:
Luca Sforzini, Annamaria Cattaneo, Clarissa Ferrari, Lorinda Turner, Nicole Mariani, Daniela Enache, Caitlin Hastings, Giulia Lombardo, Maria A. Nettis, Naghmeh Nikkheslat, Courtney Worrell, Zuzanna Zajkowska, Melisa Kose, Nadia Cattane, Nicola Lopizzo, Monica Mazzelli, Linda Pointon, Philip J. Cowen, Jonathan Cavanagh, Neil A. Harrison, Declan Jones, Wayne C. Drevets, Valeria Mondelli, Edward T. Bullmore, Neuroimmunology of Mood Disorders and Alzheimer’s Disease (NIMA) Consortium, Carmine M. Pariante
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Compelling evidence demonstrates that some individuals suffering from major depressive disorder (MDD) exhibit increased levels of inflammation. Most studies focus on inflammation-related proteins, such as serum or plasma C-reactive protein (
Externí odkaz:
https://doaj.org/article/87d95fa49cc948a699d846cef59416df
Autor:
Michael J. Colwell, Hosana Tagomori, Sarah Chapman, Amy L. Gillespie, Philip J. Cowen, Catherine J. Harmer, Susannah E. Murphy
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Impaired cognition is often overlooked in the clinical management of depression, despite its association with poor psychosocial functioning and reduced clinical engagement. There is an outstanding need for new treatments to address this unme
Externí odkaz:
https://doaj.org/article/c95d063c6a8144c9893ced8886105901
Autor:
Shona Waters, Riccardo De Giorgi, Alice M. G. Quinton, Amy L. Gillespie, Susannah E. Murphy, Philip J. Cowen, Catherine J. Harmer
Publikováno v:
BJPsych Open, Vol 9 (2023)
Background Evidence suggests inflammation may be a key mechanism by which psychosocial stress, including loneliness, predisposes to depression. Observational and clinical studies have suggested simvastatin, with its anti-inflammatory properties, may
Externí odkaz:
https://doaj.org/article/b79a2803bb724bb284cb8eb11088c530