Zobrazeno 1 - 10
of 343
pro vyhledávání: '"J. Cossman"'
Autor:
J. Cossman, M. Raffeld
Publikováno v:
Biological Applications of Anti-Idiotypes ISBN: 9781351070225
Therapeutic intervention with anti-idiotype (anti-Id) antibody offers an attractive biological approach for the clinical management of human B-cell neoplasia. Because idiotype (Id) is essentially a tumor-specific antigen, it theoretically could serve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5885cbefc2a65f33279039c664b3a872
https://doi.org/10.1201/9781351070225-9
https://doi.org/10.1201/9781351070225-9
Autor:
Raymond L. Woosley, J Cossman
Publikováno v:
Clinical Pharmacology & Therapeutics. 81:129-133
Advances in biomedical research over recent decades have substantially raised expectations that the pharmaceutical industry will generate increasing numbers of safe and effective therapies. However, there are warning signs of serious limitations in t
Publikováno v:
The Journal of Immunology. 152:3294-3305
Recent studies of transgenic mice have confirmed that clonal deletion is involved in the development of B cells. However, little is known about intercellular and intracellular molecular events regulating B cell clonal deletion. We investigated the ro
Publikováno v:
Journal of Pediatric Hematology/Oncology. 12:480-489
Diagnostic pathology and hematology have been enormously helped by recent advances in laboratory techniques that enable sensitive detection and more accurate and reproducible classification of lymphoproliferative processes. This review will focus on
Akademický článek
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Autor:
J, Cossman, C M, Annunziata, S, Barash, L, Staudt, P, Dillon, W W, He, P, Ricciardi-Castagnoli, C A, Rosen, K C, Carter
Publikováno v:
Blood. 94(2)
The malignant Reed-Sternberg cell of Hodgkin's disease, first described a century ago, has resisted in-depth analysis due to its extreme rarity in lymphomatous tissue. To directly study its genome-wide gene expression, approximately 11,000,000 bases
Publikováno v:
Hematopathology and molecular hematology. 11(1)
Nonrandom use of immunoglobulin variable (V) gene segments is a feature of some B-cell neoplasms, possibly as a consequence of antigen selection. In Hodgkin's disease, the primary tissues, cell lines, and even single Reed-Sternberg cells can carry im
Autor:
C E, Freter, J, Cossman
Publikováno v:
Seminars in oncology. 20(6)
Publikováno v:
Cancer research. 53(18)
Previous studies have shown that bcl-2 overexpression can inhibit apoptosis induced by DNA-damaging agents widely used in cancer chemotherapy, including X-irradiation, alkylating agents (hydroperoxycyclophosphamide, etc.), and topoisomerase II inhibi
Publikováno v:
Annals of oncology : official journal of the European Society for Medical Oncology. 3
Summary The following manuscript reviews data presented at the Cologne meeting relating to oncogene expression in Hodgkin's disease. Presented data ranged from investigations of oncogene expression in cell lines, where transcripts of unique size were