Zobrazeno 1 - 10
of 109
pro vyhledávání: '"J. Coito"'
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137642 (2015)
Hepatic ischemia and reperfusion injury (IRI) is an inflammatory condition and a significant cause of morbidity and mortality after surgery. Matrix metalloproteinases (MMPs) have been widely implicated in the pathogenesis of inflammatory diseases. Am
Externí odkaz:
https://doaj.org/article/b61d2c13a4344a5c8edc7bc0be615e13
Autor:
Changyong Li, Ronald W. Busuttil, Sergio Duarte, Bibo Ke, Mingwei Sheng, Dongwei Xu, Jerzy W. Kupiec-Weglinski, Ana J. Coito, Jianjun Zhu, Andrew Zhong, Yuting Jin, Song Wei, Qiang Xia
Publikováno v:
Cellular and Molecular Immunology
Notch signaling plays important roles in the regulation of immune cell functioning during the inflammatory response. Activation of the innate immune signaling receptor NLRP3 promotes inflammation in injured tissue. However, it remains unknown whether
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ff0e1729547f75764b73ee1d4f6b917
https://doi.org/10.1038/s41423-019-0318-x
https://doi.org/10.1038/s41423-019-0318-x
Autor:
Douglas G. Farmer, Ana J. Coito, Ronald W. Busuttil, Longfeng Jiang, Jerzy W. Kupiec-Weglinski, Yuanbang Lin, Mingwei Sheng, Changyong Li, Yizhu Tian, Dongwei Xu, Yongqiang Zhan, Bibo Ke
Publikováno v:
Cell death and differentiation, vol 28, iss 5
Cell Death and Differentiation
Cell Death and Differentiation
Foxo1 transcription factor is an evolutionarily conserved regulator of cell metabolism, oxidative stress, inflammation, and apoptosis. Activation of Hedgehog/Gli signaling is known to regulate cell growth, differentiation, and immune function. Howeve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31792364a73ec3b89eecfc945ec4cc48
https://escholarship.org/uc/item/2j12c2n5
https://escholarship.org/uc/item/2j12c2n5
Publikováno v:
Clinical and Developmental Immunology, Vol 7, Iss 2-4, Pp 239-248 (2000)
Externí odkaz:
https://doaj.org/article/9b98d700e14f4990bf234e90e032f8a1
Autor:
Sergio Duarte, Hiroyuki Kato, Naohisa Kuriyama, Kathryn Suko, Tomo-O Ishikawa, Ronald W Busuttil, Harvey R Herschman, Ana J Coito
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96913 (2014)
Cyclooxygenase-2 (COX-2) is a mediator of hepatic ischemia and reperfusion injury (IRI). While both global COX-2 deletion and pharmacologic COX-2 inhibition ameliorate liver IRI, the clinical use of COX-2 inhibitors has been linked to increased risks
Externí odkaz:
https://doaj.org/article/279d1661076d452ba953a4a4a39cd108
Publikováno v:
Open Schools Journal for Open Science; Vol. 3 No. 4
The students started by identifying the most vulnerable ecosystems in the vicinity of the school. The stream Ribeira da Lage was identified and this ecosystem was characterized and the possible sources of pollution were surveyed. Macroinvertebrates w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a455f17e92ce84f9651dd943f5f97ef
Publikováno v:
The American Journal of Pathology. 188:1820-1832
Matrix metalloproteinase-9 (MMP-9) is abundantly expressed by infiltrating leukocytes and contributes to the pathogenesis of hepatic ischemia and reperfusion injury (IRI). On the other hand, its physiological inhibitor, the tissue inhibitor of metall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3ae1055fa7fadafbee84b740c2d3d0e
https://doi.org/10.1016/j.ajpath.2018.05.002
https://doi.org/10.1016/j.ajpath.2018.05.002
Publikováno v:
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation SocietyReferences. 26(1)
Tissue inhibitor of metalloproteinase (TIMP) 3 is a naturally occurring inhibitor of a broad range of proteases, with key roles in extracellular matrix turnover and in the pathogenesis of various diseases. In this study, we investigated the response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15b5f287257025041db3288c7db2be05
https://pubmed.ncbi.nlm.nih.gov/31642174
https://pubmed.ncbi.nlm.nih.gov/31642174
Publikováno v:
Matrix biology : journal of the International Society for Matrix Biology
The liver is a large highly vascularized organ with a central function in metabolic homeostasis, detoxification, and immunity. Due to its roles, the liver is frequently exposed to various insults which can cause cell death and hepatic dysfunction. Al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0480e8bcbf426436f05b4352f8f151a7
http://europepmc.org/articles/PMC4495728
http://europepmc.org/articles/PMC4495728
Publikováno v:
American Journal of Transplantation. 12:2689-2699
Liver ischemia-reperfusion injury (IRI) remains a challenging problem in clinical settings. The expression of fibronectin (FN) by endothelial cells is a prominent feature of the hepatic response to injury. Here we investigate the effects of the conne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4bdfc7810cc07d97172023bf98f6c74
https://doi.org/10.1111/j.1600-6143.2012.04161.x
https://doi.org/10.1111/j.1600-6143.2012.04161.x