Zobrazeno 1 - 2
of 2
pro vyhledávání: '"J. Chuck Poole"'
Autor:
Christie Schulte, Curt D. Haffner, J. Chuck Poole, Eric E. Boros, John C. Ulrich, David J. Cowan, Tiffany Carpenter, Eugene L. Stewart, J. Darren Stuart, Frank Preugschat, David N. Deaton, Tara Renae Rheault, Todd W. Shearer, Barry G. Shearer, J. David Becherer, Michael R. Jeune, Istvan Kaldor, Lisa M. Shewchuk, Terrence L. Smalley
Publikováno v:
Journal of medicinal chemistry. 58(17)
Starting from the micromolar 8-quinoline carboxamide high-throughput screening hit 1a, a systematic exploration of the structure-activity relationships (SAR) of the 4-, 6-, and 8-substituents of the quinoline ring resulted in the identification of ap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3658483777ab9fbd90af6214b321302c
https://pubmed.ncbi.nlm.nih.gov/26267483
https://pubmed.ncbi.nlm.nih.gov/26267483
Autor:
Julie L. Geary, Melinda A. Correll, J. Chuck Poole, Xiao-Gao Liu, Larry D. Bratton, Fred E. Boyer, Thomas N. Thompson, Teng-Man Chen, Arun K. Mandagere, Bryan K. Jones, Kin-Kai Hwang, Mark E. Webster, Robert W. Knippenberg, Maynard George D, Stephen W. Horgan, Deborah E. Logan, Tieu-Binh Le, Kudlacz Elizabeth M, David L. Wenstrup, Burkholder Timothy P, Raymond S. Gross, David W. Freund
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 7:2531-2536
We recently described the synthesis and characterization of MDL 105,212, a non peptide tachykinin antagonist with high affinity for NK1 and NK2 receptors.1 Here we report the synthesis and structure-activity relationships for a series of analogs of M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6a5ed5f48c9a57f6ec7d3becd618960
https://doi.org/10.1016/s0960-894x(97)10013-0
https://doi.org/10.1016/s0960-894x(97)10013-0