Zobrazeno 1 - 10
of 74
pro vyhledávání: '"J. Christopher Luft"'
Publikováno v:
ACS Omega, Vol 4, Iss 3, Pp 5547-5555 (2019)
Externí odkaz:
https://doaj.org/article/e4c3813dd8354b7486b53790dae5c0fa
Autor:
Anil K. Sood, Joseph M. DeSimone, Gabriel Lopez-Berestein, Mary E. Napier, J. Christopher Luft, Sherry Y. Wu, Tojan B. Rahhal, Guillermo N. Armaiz-Pena, Rajesha Rupaimoole, Hee-Dong Han, Selanere L. Mangala, Sunila Pradeep, Takahito Miyake, Charles J. Bowerman, Kevin S. Chu, Kshipra M. Gharpure
The purpose of this study was to investigate the antitumor effects of a combination of metronomic doses of a novel delivery vehicle, PLGA-PRINT nanoparticles containing docetaxel, and antiangiogenic mEZH2 siRNA incorporated into chitosan nanoparticle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30a188044627a967a0ce282db6a567ca
https://doi.org/10.1158/1535-7163.c.6536302
https://doi.org/10.1158/1535-7163.c.6536302
Autor:
Anil K. Sood, Joseph M. DeSimone, Gabriel Lopez-Berestein, Mary E. Napier, J. Christopher Luft, Sherry Y. Wu, Tojan B. Rahhal, Guillermo N. Armaiz-Pena, Rajesha Rupaimoole, Hee-Dong Han, Selanere L. Mangala, Sunila Pradeep, Takahito Miyake, Charles J. Bowerman, Kevin S. Chu, Kshipra M. Gharpure
PDF - 312K, Storage stability of PLGA-PRINT nanoparticles.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9d13e0c74f4f3ad0f756e3f6e3ea614
https://doi.org/10.1158/1535-7163.22499896
https://doi.org/10.1158/1535-7163.22499896
Autor:
Anil K. Sood, Joseph M. DeSimone, Gabriel Lopez-Berestein, Mary E. Napier, J. Christopher Luft, Sherry Y. Wu, Tojan B. Rahhal, Guillermo N. Armaiz-Pena, Rajesha Rupaimoole, Hee-Dong Han, Selanere L. Mangala, Sunila Pradeep, Takahito Miyake, Charles J. Bowerman, Kevin S. Chu, Kshipra M. Gharpure
PDF - 78K, Supplementary methods and legends for supplementary figures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0adbde2c5fbb743e2736244bc1737b3
https://doi.org/10.1158/1535-7163.22499899
https://doi.org/10.1158/1535-7163.22499899
Autor:
J. Christopher Luft, Nisitha Sengottuvel, Joseph M. DeSimone, Shaomin Tian, Emily B. Harrison, Balachandra K. Gorentla, Jenny P.-Y. Ting, Chintan H. Kapadia, Ning Cheng, Chad V. Pecot, Jillian L. Perry
Publikováno v:
ACS Nano
CpG oligodeoxynucleotides are potent toll-like receptor (TLR) 9 agonists and have shown promise as anticancer agents in preclinical studies and clinical trials. Binding of CpG to TLR9 initiates a cascade of innate and adaptive immune responses, begin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18344900f19ee8fdf7bdb2975763fcef
https://doi.org/10.1021/acsnano.0c02207
https://doi.org/10.1021/acsnano.0c02207
Autor:
Sylvia Hiller, J. Christopher Luft, Zhenquan Jia, Xianwen Yi, Joseph M. DeSimone, Jun Nakamura, Shaomin Tian, Ying Wang
Publikováno v:
Journal of Biomedical Nanotechnology. 16:467-480
We developed a vaccine formulation containing ApoB derived P210 peptides as autoantigens, retinoic acid (RA) as an immune enhancer, both of which were delivered using PLGA nanoparticles. The formula was used to induce an immune response in 12-week-ol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7028eb57d7b008fb99882d382824f8cf
https://doi.org/10.1166/jbn.2020.2905
https://doi.org/10.1166/jbn.2020.2905
Publikováno v:
ACS Omega
ACS Omega, Vol 4, Iss 3, Pp 5547-5555 (2019)
ACS Omega, Vol 4, Iss 3, Pp 5547-5555 (2019)
Multiple studies have been published emphasizing the significant role of nanoparticle (NP) carriers in antigenic peptide-based subunit vaccines for the induction of potent humoral and cellular responses. Various design parameters of nanoparticle subu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04732783c7d0c61561e9d56daafe9cf4
http://europepmc.org/articles/PMC6450662
http://europepmc.org/articles/PMC6450662
Publikováno v:
Nanoscale. 11:1847-1855
The starting hypothesis for this work was that microwave synthesis could enable the rapid assembly of polymers into size-specific nanoparticles (NPs). The Zapped Assembly of Polymeric (ZAP) NPs was initially realized using poly(lactic-co-glycolic aci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77393e40a25cc8248866673ca247d235
https://doi.org/10.1039/c8nr09944h
https://doi.org/10.1039/c8nr09944h
Autor:
Roberto Mota, Stephen W. Simington, Joseph M. DeSimone, Darcy Holley, Xianwen Yi, Jun Nakamura, Zhenquan Jia, Nobuyo Maeda, Monte S. Willis, Shaomin Tian, Sylvia Hiller, J. Christopher Luft, Scott J. Bultman
Publikováno v:
Vascul Pharmacol
Atherosclerosis is a systemic chronic inflammatory disease. Many antioxidants including alpha-lipoic acid (LA), a product of lipoic acid synthase (Lias), have proven to be effective for treatment of this disease. However, the question remains whether
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44e7cf17f4c19813d7b3f8cec41bcf24
https://europepmc.org/articles/PMC8020442/
https://europepmc.org/articles/PMC8020442/
Autor:
Russell J. Mumper, S. Rahima Benhabbour, Shamit S. Prabhu, Matthew C. Parrott, Denis R. Beckford Vera, J. Christopher Luft, Dylan M. Glatt
Publikováno v:
Molecular Pharmaceutics. 15:5089-5102
The safety and efficacy of anticancer antibody-drug conjugates (ADCs) depend on the selection of tumor-targeting monoclonal antibody (mAb), linker, and drug, as well as their specific chemical arrangement and linkage chemistry. In this study, we used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d66ceac5c62962bf8a329bd232dbbf95
https://doi.org/10.1021/acs.molpharmaceut.8b00672
https://doi.org/10.1021/acs.molpharmaceut.8b00672