Zobrazeno 1 - 10
of 254
pro vyhledávání: '"J. Chapal"'
Autor:
S. Dietz, J. Chapal, Dominique Hillaire-Buys, Marie-Madeleine Loubatières-Mariani, Pierre Petit
Publikováno v:
Journal de la Société de Biologie. 193:57-61
Nous avons etudie, sur le lit vasculaire pancreatique du Rat, les effets de l’ATP dans deux conditions experimentales differentes. 1) En presence d’indome-thacine, inhibiteur de la cyclooxygenase et de la formation de prostacycline (PGI2), l’AT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a04311b4a482ca3520dddfa68267c203
https://doi.org/10.1051/jbio/1999193010057
https://doi.org/10.1051/jbio/1999193010057
Autor:
Pierre Petit, M Manteghetti, Dominique Hillaire-Buys, S Debrus, Marie-Madeleine Loubatières-Mariani, J. Chapal
Publikováno v:
British Journal of Pharmacology. 125:1368-1374
Adenine nucleotides have been shown to stimulate insulin secretion by acting on P2 receptors of the P2Y type. Since there have been some discrepancies in the insulin response of different analogues of ATP and ADP, we investigated whether two differen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2bc71c3d3fc50a63a4b5456d28c12786
https://doi.org/10.1038/sj.bjp.0702214
https://doi.org/10.1038/sj.bjp.0702214
Autor:
Marie-Madeleine Loubatières-Mariani, Pierre Petit, J. Chapal, Dominique Hillaire-Buys, J. P. Blayac, N. Linck
Publikováno v:
British Journal of Pharmacology. 124:149-156
We have previously demonstrated that adenosine-5′-O-(2-thiodiphosphate) (ADPβS), a potent P2Y-purinoceptor agonist, relaxed pancreatic vasculature not only through prostacyclin (PGI2) and nitric oxide (NO) release from the endothelium but also thr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f323363e6053fc5a284296a33b3321c
https://doi.org/10.1038/sj.bjp.0701826
https://doi.org/10.1038/sj.bjp.0701826
Autor:
Marie-Madeleine Loubatières-Mariani, Pierre Petit, G. Bertrand, Dominique Hillaire-Buys, D Pujalte, J. Chapal
Publikováno v:
Fundamental & Clinical Pharmacology. 11:537-545
Adenosine tri- and diphosphate (ATP and ADP) and their structural analogues stimulate insulin secretion from the isolated perfused rat pancreas, an effect mediated by P2Y-purinoceptor activation. Concerning the base moiety of the nucleotide, it was p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd5a495e7760984816f180883546c89f
https://doi.org/10.1111/j.1472-8206.1997.tb00858.x
https://doi.org/10.1111/j.1472-8206.1997.tb00858.x
Autor:
Pierre Petit, C. Brunschwig, I. Quéré, J. Chapal, Dominique Hillaire-Buys, J. P. Blayac, Marie-Madeleine Loubatières-Mariani, C. Janbon
Publikováno v:
British Journal of Pharmacology. 122:351-357
1. Epidemiological and experimental data have shown that homocysteine may provoke vascular lesions and that moderate homocysteinaemia may constitute an independent risk factor for vascular disease. It is now documented that homocysteine damages human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0cecae8b33663e865ac93ecc3fe4a2e
https://doi.org/10.1038/sj.bjp.0701358
https://doi.org/10.1038/sj.bjp.0701358
Autor:
Pierre Petit, J. Chapal, G. Bertrand, Marie-Madeleine Loubatières-Mariani, Dominique Hillaire-Buys
Publikováno v:
Fundamental & Clinical Pharmacology. 8:117-127
The insulin secreting B cell is fitted with the two types of purinergic receptors: P2 (for ATP and/or ADP) and P1 (for adenosine). The activation of P2 purinoceptors by ATP or ADP evokes a biphasic stimulation of insulin secretion from isolated perfu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::957800af3a703a4a2a5d72aa26a7fdde
https://doi.org/10.1111/j.1472-8206.1994.tb00788.x
https://doi.org/10.1111/j.1472-8206.1994.tb00788.x
Publikováno v:
Scopus-Elsevier
A possible implication of endogenously released ATP and (or) ADP in insulin response to glucose stimulation was investigated in the isolated rat pancreas. The first phase of insulin response to the same glucose concentration (8.3 mM) was much higher
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::059177c3c585ad75c12d8a6cd896af74
https://doi.org/10.1139/y93-086
https://doi.org/10.1139/y93-086
Publikováno v:
British Journal of Pharmacology. 102:627-630
1. The effects of a P2 purinoceptor agonist, adenosine 5'-O-(2-thiodiphosphate) (ADP-beta-S) have been studied on insulin secretion and flow rate of the isolated perfused pancreas of the rat. 2. In the presence of a moderately stimulating glucose con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d31b77688d5dd07d12306c7ac02b467b
https://doi.org/10.1111/j.1476-5381.1991.tb12223.x
https://doi.org/10.1111/j.1476-5381.1991.tb12223.x
Publikováno v:
Fundamental & Clinical Pharmacology. 4:201-212
Summary— The action of a water soluble benzodiazepine, chlordiazepoxide (CDZ) on the stimulatory effect of adenosine on glucagon secretion from the isolated pancreas of the rat perfused in presence of 2.8 mM glucose was studied. CDZ 10−7 and 10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::927d795f2f1df8c0981b5f09bae4ef42
https://doi.org/10.1111/j.1472-8206.1990.tb00488.x
https://doi.org/10.1111/j.1472-8206.1990.tb00488.x
Publikováno v:
Purinergic and Pyrimidinergic Signalling II ISBN: 9783540678489
Diabetes mellitus is the phenotypic expression of a disorder resulting from various environmental factors interacting with a genetic component. It is an heterogeneous metabolic syndrome consisting of a dysregulation of glucose homeostasis, with addit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5cc0d4d6e2f9b68ea5a6fb2bb296ecf
https://doi.org/10.1007/978-3-642-56921-0_12
https://doi.org/10.1007/978-3-642-56921-0_12
